geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Repeatability of heart rate variability in congenital hypothyroidism as analysed by detrended fluctuation analysis


, : Repeatability of heart rate variability in congenital hypothyroidism as analysed by detrended fluctuation analysis. Physiological Measurement 30(10): 1017-1025

The analysis of heart rate fluctuations, or heart rate variability (HRV), may be applied to explore children's neurodevelopment. However, previous studies have reported poor reliability (repeatability) of HRV measures in children at rest and during light exercise. Whether the reliability can be improved by controlling variables such as physical activity, breathing rate and tidal volume, or by selecting non-conventional techniques for analysing the data remains as an open question. We evaluated the short-term repeatability of RR-interval data from medicated children with congenital hypothyroidism (CH). The alpha(1) exponents, obtained by detrended fluctuation analysis (DFA), from the data of 21 children collected at two different sessions were compared. Elapsed days between sessions were 59 +/- 33, and data were obtained during 10 min, trying to restrict the children's activity while being seated. We found statistical agreement between the means of alpha(1) exponents for each session (p = 0.94) and no bias with a low-coefficient variation (9.1%); an intraclass correlation coefficient ri = 0.48 ([0.14 0.72], 95% confidence interval) was also estimated. These findings, which were compared with results obtained by conventional time and frequency techniques, indicate the existence of agreement between the alpha(1) exponents obtained at each session, thereby providing support concerning the repeatability of HRV data as analysed by DFA in children with congenital hypothyroidism. Of particular interest was also the agreement found by using the central frequency of the high-frequency band and the parameter pNN20, both showing better or similar ri than alpha(1) (0.77 [0.57 0.89] and 0.51 [0.17 0.74], respectively), yet considerably better repeatability than other conventional time and frequency parameters.

US$19.90

PMID: 19706959

DOI: 10.1088/0967-3334/30/10/003


Other references

Nishigaki, K.; Thompson, D.; Yugawa, T.; Rulli, K.; Hanson, C.; Cmarik, J.; Gutkind, J.Silvio.; Teramoto, H.; Ruscetti, S., 2003: Identification and characterization of a novel Ste20/germinal center kinase-related kinase, polyploidy-associated protein kinase. A novel protein kinase, polyploidy-associated protein kinase (PAPK), was isolated using a subtraction cDNA library approach from a mouse erythroleukemia cell line that had been induced to polyploidy after serum withdrawal. PAPK shares homology wit...

Miller, S.L.; Hazrati, Y.; Cornwall, R.; Hayes, P.; Gothelf, T.; Gladstone, J.L.; Flatow, E.L., 2002: Failed surgical management of partial thickness rotator cuff tears. Some authors have recommended that rotator cuff tears <50% of tendon thickness be debrided and those involving >50% of the tendon be treated with miniopen repair. We hypothesize that if indications for selecting between simple debridement an...

Stockbrügger, R.W.; Armbrecht, U.; Müller, E.; Heusinger, A., 1991: Determination of faecal chymotrypsin concentration and 72-hour faecal chymotrypsin output in the detection of pancreatic steatorrhoea. In 96 consecutive patients who underwent a 72-h faecal fat determination because of suspected nutrient malassimilation (maldigestion and/or malabsorption) faecal chymotrypsin (F-Chym) was estimated with a commercial photometric test (Monotest Chym...

Yu, B.; Wang, Y.; Liu, Y.; Liu, Y.; Li, X.; Wu, D.; Zong, Z.; Zhang, J.; Yu, D., 2004: Protein kinase A regulates cell cycle progression of mouse fertilized eggs by means of MPF. Cell cycle of one-cell stage mouse fertilized eggs was accompanied by fluctuation in the concentration of adenosine 3'5'-monophosphate (cAMP) and in the activity of free catalytic subunit of cAMP-dependent protein kinase (PKA). The conce...

Viera, A.J.; Neutze, D.M., 2011: Diagnosis of secondary hypertension: an age-based approach. Secondary hypertension is a type of hypertension with an underlying, potentially correctable cause. A secondary etiology may be suggested by symptoms (e.g., flushing and sweating suggestive of pheochromocytoma), examina- tion findings (e.g., a ren...

Fossati, C., 1974: Liver damage due to drugs. II. La Clinica Terapeutica 68(2): 171-184

Verheij, E.W.M.; Van Lookeren Campagne, P., 1968: A pruning trial comparing hydraulic and hand implements. In a 3-year pruning trial with Cox's Orange Pippin on M.IV and M.XVI and Golden Delicious on M.IV, pruning with a hydraulic machine resulted in an average loss of crop of approximately 15 % compared with hand pruning. The differences were lea...

Borisov, A.E.; Kubachev, K.G.; Mukhuddinov, N.D.; Turdyev, M.S.; El'muradov, K.S., 2007: Diagnostics and surgical treatment of isolated and associated injuries of the liver. The authors have analyzed results of treatment of 388 patients with open and closed injuries of the liver and the diagnostic potential of different instrumental methods. The optimal diagnostic algorithm is proposed. The validity of using videoscop...

Stewart, M.C.; Wang, Y., 2001: Regulation of BMP expression by thyroid hormone in differentiating chondrocytes. Journal of Bone & Mineral Research 16(Suppl 1): S320, September

Baum, B.J.; Bird, J.L.; Longton, R.W., 1977: Histidine-rich-polypeptides in Macaque parotid saliva are not nuclear histones. Archives of Oral Biology 22(7): 455-456