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Republished review: Ocular manifestations of the antiphospholipid syndrome


, : Republished review: Ocular manifestations of the antiphospholipid syndrome. Postgraduate Medical Journal 87(1029): 496-501

Antiphospholipid syndrome (APS) is an autoimmune disease characterised by a heterogenous group of antibodies directed against negatively charged phospholipids including antiphospholipid antibodies (aPL), anticardiolipin antibodies (aCL) and β-2 glycoprotein I (aβ-2-GP1). The major features of this disorder include arterial and venous thrombosis and recurrent fetal loss. The vasculature of the eye is frequently involved and may be the presenting manifestation. A diagnosis of APS should be considered in a young patients without traditional thromboembolic risk factors presenting with ocular vaso-occlusive disease. Management of these patients involves a team-approach with a haematologist/oncologist or rheumatologist to manage the coagulation status of these patients to prevent further systemic vascular occlusions.

US$19.90

PMID: 21705776

DOI: 10.1136/pgmj.2010.182857rep


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