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Residual antibacterial activity of chlorhexidine digluconate and camphorated p-monochlorophenol in calcium hydroxide-based root canal dressings


, : Residual antibacterial activity of chlorhexidine digluconate and camphorated p-monochlorophenol in calcium hydroxide-based root canal dressings. Brazilian Dental Journal 18(1): 8-15

The purpose of this study was to evaluate the residual antibacterial activity of several calcium hydroxide [Ca(OH)2]-based pastes, placed in root canals of dogs' teeth with induced chronic periapical lesions. Root canals were instrumented with the ProFile rotary system and filled with 4 pastes: G1 (n=16): Ca(OH)2 paste + anesthetic solution; G2 (n=20): Calen paste + camphorated p-monochlorophenol (CMCP); G3 (n=18): Calen; and G4 (n=18): Ca(OH)2 paste + 2% chlorhexidine digluconate. After 21 days, the pastes were removed with size 60 K-files and placed on Petri plates with agar inoculated with Micrococcus luteus ATCC 9341. Pastes that were not placed into root canals served as control. After pre-diffusion, incubation and optimization, the inhibition zones of bacterial growth were measured and analyzed by Mann-Whitney U test at 5% significance level. All pastes showed residual antibacterial activity. The control samples had larger halos (p<0.05). The mean residual antibacterial activity halos in G1, G2, G3 and G4 were 7.6; 10.4; 17.7 and 21.4 mm, respectively. The zones of bacterial growth of G4 were significantly larger than those of G1 and G2 (p<0.05). In conclusion, regardless of the vehicle and antiseptic, all Ca(OH)2-based pastes showed different degrees of measurable residual antibacterial activity. Furthermore, unlike CMCP, chlorhexidine increased significantly the antibacterial activity of Ca(OH)2.

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PMID: 17639193


Other references

Springer, T.A.; Strominger, J.L.; Mann, D., 1974: Partial purification of detergent-soluble HL-A antigen and its cleavage by papain. HL-A antigen solubilized with the non-ionic detergent, Brij 99, has been purified to about 50% of homogeneity from a cultured human lymphoblast line. It consists of two nonidentical subunits of 44,000 and 12,000 molecular weight (MW). Upon papain...

Mahlo, A., 1954: Fine relief of the stomach. Fortschritte auf dem Gebiete der Rontgenstrahlen 81(1): 56-60

Garcia, E.; Mourad, G., 2004: A site-directed mutagenesis interrogation of the carboxy-terminal end of Arabidopsis thaliana threonine dehydratase. We fused four mutant omr1 alleles, encoding feedback-insensitive forms of Arabidopsis thaliana biosynthetic threonine dehydratase/deaminase (TD), to the CaMV 35S promoter and transformed these constructs into A. thaliana Columbia wild type plants....

Tosson, R.; Buchwald, D.; Klak, K.; Laczkovics, A., 2001: The impact of hypertension on the operative and early postoperative outcome of aortic valve surgery. Hypertension is a known risk factor in heart disease. It can lead to pressure overload and hypertrophy of the left ventricle. The aim of this study is to examine the effect of hypertension on the operative and early postoperative outcome after aor...

Bondarenko V.I.; Nadezhnyy A.M., 1985: The main features of structure and morphology of the volcanic zone and some submarine volcanoes near the Catwic-Phu Quy Islands on the Vietnamese Shelf as shown by data from continuous seismic profiling. Vulkanologiya i Seysmologiya 1985(5): 34-43

Davidson, A.; Poutias, D.N.; Cowan, D.B.; Del Nido, P.J.; Mcgowan, F.X., 2001: Hypoxia causes oxyradical production in immature astrocytes. Circulation 104(17 Supplement): II 646, October 23

McGilvery Thomas A.; Berlau Charles E., 1980: Stratigraphic relationships of the Brentwood and Woolsey members, Bloyd Formation (type Morrowan), northwestern Arkansas. Proceedings of the Arkansas Academy of Science 34: 80-83

Issel, L.Michele.; Baldwin, K.A.; Lyons, R.L.; Madamala, K., 2006: Self-reported competency of public health nurses and faculty in Illinois. Having a public health workforce with a high level of competency is a prerequisite for having an effective public health system. The purpose of these two studies was to assess the competency level of practicing public health nurses (PHNs; n=168) f...

Mandal, T.; Zhao, C-Gui., 2008: Modularly designed organocatalytic assemblies for direct nitro-Michael addition reactions. Angewandte Chemie 47(40): 7714-7717

Neylon, C.B.; Irvine, R.F., 1990: Synchronized repetitive spikes in cytoplasmic calcium in confluent monolayers of human umbilical vein endothelial cells. Synchronized repetitive spikes in cytoplasmic free calcium concentration, [Ca2+]i, are evoked by histamine in confluent monolayers of human endothelial cells. The repetitive spikes, which are apparently dependent upon the establishment of cell cou...