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Revascularization after segmental resection of lower extremity soft tissue sarcomas


, : Revascularization after segmental resection of lower extremity soft tissue sarcomas. Journal of Surgical Oncology 95(6): 455-460

Limb salvage surgery combined with vascular reconstruction has replaced amputation as the preferred treatment of soft tissue sarcomas involving major vascular structures of the extremities. We describe our experience with soft tissue sarcomas involving major vascular structures and examine outcomes according to the type of graft selected for arterial reconstruction. We also examine the effect of venous reconstruction on post-operative edema. This retrospective review includes 14 patients with lower extremity soft-tissue sarcomas that encased major vessels, requiring combined limb-preserving tumor resection and revascularization with a synthetic or autogenous saphenous vein graft. Edema in patients with and without venous reconstruction was compared. The incidence of infection, wound dehiscence, and graft thrombosis were compared according to arterial graft type. There was no significant difference in edema in patients with venous reconstruction and those without. There was also no significant difference in infection and graft thrombosis in patients with synthetic grafts and those with autogenous saphenous vein grafts. Wound dehiscence occurred more often in patients with synthetic grafts (P = 0.029). Although this study was small, these results suggest that further studies are needed to determine the roles that vascular graft selection and venous reconstruction play in clinical outcome.

US$19.90

PMID: 17458861

DOI: 10.1002/jso.20679


Other references

Eason, EH., 1993: A new species of Anopsobius from the Falkland Islands, with commentary on the geographical distribution of the genus Chilopoda Lithobiomorpha. Myriapodologica, 212: 83-89

Ozerov, A.L., 1993: New Palaearctic species of the genus Norellia (Diptera, Scathophagidae). Norellia montanopratensis sp. n. (Northern Osetia) -allied to N. femoralis (Lw.), differs by antennae and middle tibia colour. N. caucasica sp. n. (Northern Osetia) closely allied to N. montanopratensis sp. n differs by vibrissa position as relate...

Andrew M.E.; Coupar B.E.H.; Boyle D.B.; Bellamy A.R.; Both G.W., 1987: Immune recognition of rotavirus antigens expressed by recombinant vaccinia viruses. Chanock, R M , Et Al (Ed ) Vaccines, 87 Modern Approaches to New Vaccines: Prevention Of Aids And Other Viral, Bacterial, And Parasitic Diseases; Conference, Cold Spring Harbor, New York, Usa, 1986 Xxiii+461p Cold Spring Harbor Laboratory: Cold Spring Harbor, New York, Usa Illus Paper 408-411

Szakacs Dobozi M., 1982: Chromato focusing method for the purification and separation of cellulase enzyme components. Acta Biochimica Et Biophysica Academiae Scientiarum Hungaricae2: 131

Tannuri, U., 1996: Biliary atresia - evolution in the last two decades. Jornal de Pediatria 72(1): 1-3

Totolian, A.A., 1962: On the study of streptococcal bacteriophages (on properties of antiphage sera). Zhurnal Mikrobiologii, Epidemiologii, i Immunobiologii 33: 83-88

Gaido, P.C.; Capellaro, F., 1962: The influence of relaxation on some aspects of water-salt balance during muscular work at high temperatures. Minerva Medica 53: 1215-1216

Prasad, B.Deo.; Creissen, G.; Lamb, C.; Chattoo, B.B., 2010: Overexpression of rice (Oryza sativa L.) OsCDR1 leads to constitutive activation of defense responses in rice and Arabidopsis. Plant aspartic proteases (AP) play key roles in the regulation of biological processes, such as the recognition of pathogens and pests and the induction of effective defense responses. A large number of AP (>400) have been identified in silico...

Schmallfuss, H., 1972: Die lsopoden der lnseln Rhodos und Karpathos (Sudostagais). Zoologische Jb.: 561-609

Choi, M.S.; Choi, J.W.; Shin, C.Y.; Yoo, B.K.; Cheong, J.H.; Ryu, J.H.; Ko, K.H., 2002: Involvement of hydrogen peroxide in the synergistic death of rat primary astrocytes by immunostimulation and glucose deprivation. In this study, the role of H2O2 on the glial dysfunction and toxicity was investigated. Immunostimulated rat primary astrocytes with LPS plus IFN-gamma for 48h produced a large amount of H2O2, which prevented by the co-treatment of H2O2 scavenger,...