geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Risk factors for mastectomy flap necrosis following immediate tissue expander breast reconstruction


, : Risk factors for mastectomy flap necrosis following immediate tissue expander breast reconstruction. Journal of Plastic Surgery and Hand Surgery 48(5): 322-326

Tissue expander placement is a mainstay of reconstructive surgery in the post-mastectomy patient. Necrosis of the native breast tissue is one of the most significant concerns in their post-operative care. The goal of this study is to elucidate factors that confer risk of this outcome. Chart review was conducted for a consecutive series of immediate tissue expander reconstructions by the two senior authors. Data was collected for several preoperative and intraoperative variables, as well as the outcome of mastectomy flap necrosis. Of the 1566 breasts that were examined, 135 (8.6%) experienced flap necrosis. The cohorts with and without flap necrosis were well matched. Those with the outcome of interest had significantly higher rates of switching to an autologous method of reconstruction (31.9% vs 6.2%, p < 0.001). Regression analysis revealed smoking status, increased age, tumescent mastectomy technique, and high (>66.67%) intraoperative tissue expander fill to confer increased risk of mastectomy flap necrosis. While smoking and older age are well-supported by the literature, tumescent technique and tissue expander fill are more novel points of discussion, which may serve as proxies for other issues. Awareness of these risk factors and their interplay will aid in clinical judgement and postoperative care of these patients.

US$19.90

PMID: 24495186

DOI: 10.3109/2000656X.2014.884973


Other references

Qureshi, A.I.; Suri, M.Fareed.K.; Ostrow, P.T.; Kim, S.H.; Ali, Z.; Shatla, A.A.; Guterman, L.R.; Hopkins, L.Nelson., 2003: Apoptosis as a form of cell death in intracerebral hemorrhage. OBJECTIVE: The goals of this study were to identify and quantify the presence of programmed cell death (apoptosis) in intracerebral hemorrhage (ICH) among human subjects. Recent evidence from laboratory models suggests that cell death in the perih...

Bejarano, A., C.; Van-Dolah, F., M.; Gulland, F., M.; Schwacke, L., 2007: Exposure assessment of the biotoxin domoic acid in California sea lions: application of a bioenergetic model. The biotoxin domoic acid (DA), produced by diatoms of the genus Pseudo-nitzschia, has caused massive California sea lion Zalophus californianus mortalities and live strandings along the California coast. Since quantifying the field DA dose that c...

Govorov, V.P., 1958: The effect of Gomphocarpus on cardiac activity inhibited by drugs. An alcoholic extract of the leaves of Gomphocarpus fruticosus had a beneficial effect on cardiac activity (a heart and lung preparation) which had been weakened by peptone, quinine or chloralhydrate. The action of the extract of Gomphocarpus on th...

Bercin, S.; Cetnkaya, Z.; Bulut, Y.; Akpolat, N.; Aygen, E., 2006: Effects of Egb-761 in rats with obstructive jaundice. A study was undertaken to investigate the effects of Ginkgo biloba extract (EGb-761) on the liver and terminal ileum morphology, biochemical parameters and bacterial translocation in rats with obstructive jaundice. Forty-four Wistar Albino rats we...

Jolley, A.E., 1993: The value of surveillance cultures on neonatal intensive care units. Nosocomial infections on neonatal intensive care units (NICUs) have been a recognized cause for concern for many years. It is the endeavour of the doctors caring for these children to identify and treat such infections as early as possible in an e...

Grassi Zucconi, G.; Carandente, F.; Menichini, E.; Belia, S.; Giuditta, A., 1988: Circadian rhythms of DNA content in brain and kidney: effects of environmental stimulation. Male adult Wistar rats kept under natural lighting show circadian rhythms of DNA content and DNA synthesis in the cerebral cortex, cerebellum and kidney. In the cerebral cortex the acrophases of the 2 rhythms almost coincide during the dark period...

Miles, S., 1996: A case of death by physical restraint: new lessons from a photograph. Journal of the American Geriatrics Society 44(3): 291-292

Selim, H.S.; Hammouda, A.Fattah.A.; Sadek, N.A.; Ahmed, M.A.; Al-Kadassy, A.M., 2008: Fungal Infection among Patients with Some Hematopoietic Disorders. With the increasing number of immune compromised patients suffering from hematological disorders, invasive fungal infections have emerged as a major cause of morbidity and mortality among these patients. This study evaluated the use of conventiona...

Hiramatsu, S.; Osaki, H.; Miki, Y., 1959: Studies on the oral administration of gramicidin J1. Following oral administration to mice, gramicidin J1 demonstrates very low toxicity, whereas following parenteral administration, it shows considerable toxicity. Gramicidin J1 is not hydrolyzed by trypsin or microorganisms in the intestine. Gramic...

Brody J.I., 1967: The induction of antibody synthesis in neopl leukemic lymphocytes by immune lymphocyte extracts abstract. Blood 30(6): 884-885