geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Risk of classic Kaposi sarcoma with exposures to plants and soils in Sicily


, : Risk of classic Kaposi sarcoma with exposures to plants and soils in Sicily. Infectious Agents and Cancer 5(1): 23-23

Ecologic and in vitro studies suggest that exposures to plants or soil may influence risk of Kaposi sarcoma (KS). In a population-based study of Sicily, we analyzed data on contact with 20 plants and residential exposure to 17 soils reported by 122 classic KS cases and 840 sex- and age-matched controls. With 88 KS-associated herpesvirus (KSHV) seropositive controls as the referent group, novel correlates of KS risk were sought, along with factors distinguishing seronegatives, in multinomial logistic regression models that included matching variables and known KS cofactors - smoking, cortisone use, and diabetes history. All plants were summed for cumulative exposure. Factor and cluster analyses were used to obtain scores and groups, respectively. Individual plants and soils in three levels of exposure with Ptrend ≤ 0.15 were retained in a backward elimination regression model. Adjusted for known cofactors, KS was not related to cumulative exposures to 20 plants [per quartile adjusted odds ratio (ORadj) 0.96, 95% confidence interval (CI) 0.73 - 1.25, Ptrend = 0.87], nor was it related to any factor scores or cluster of plants (P = 0.11 to 0.81). In the elimination regression model, KS risk was associated with five plants (Ptrend = 0.02 to 0.10) and with residential exposure to six soils (Ptrend = 0.01 to 0.13), including three soils (eutric regosol, chromic/pellic vertisol) used to cultivate durum wheat. None of the KS-associated plants and only one soil was also associated with KSHV serostatus. Diabetes was associated with KSHV seronegativity (ORadj 4.69, 95% CI 1.97 - 11.17), but the plant and soil associations had little effect on previous findings that KS risk was elevated for diabetics (ORadj 7.47, 95% CI 3.04 - 18.35) and lower for current and former smokers (ORadj 0.26 and 0.47, respectively, Ptrend = 0.05). KS risk was associated with exposure to a few plants and soils, but these may merely be due to chance. Study of the effects of durum wheat, which was previously associated with cKS, may be warranted.

US$19.90

PMID: 21126363

DOI: 10.1186/1750-9378-5-23


Other references

Riou, V.; Essner, M.S.; Derharoutunian, C.; Menard, B.; Dussud, C.; Roubille, R.; Galtier, H., 1999: A prospective study to evaluate drug adverse effects in two geriatric health care units in Vienne medical center. A prospective study was conducted to evaluate drug adverse effects in geriatric patients. Drug side effects were collected by pharmacy residents and validated by physicians. Then, the imputability was determined with the french method. This study...

Anonymous, 2004: Face-to-face approach proves successful for HIV/AIDS program in Florida. In the past several years, Florida legislators have pinned their hopes on a cadre of DM vendors to bring health care costs under control in that state's Medicaid program. While most of these highly publicized efforts have failed to meet the l...

Viola, L.; Chiaretti, A.; Castorina, M.; Tortorolo, L.; Piastra, M.; Villani, A.; Valentini, P.; Polidori, G., 1998: Acute hydrocephalus as a consequence of mumps meningoencephalitis. Aqueductal stenosis can result from mumps meningoencephalitis. We report a case of acute hydrocephalus from an aqueductal stenosis developed immediately after a clinically evident mumps infection. The patient, aged two years, was treated with an a...

Izhar, S.; Frankel, R., 1973: Mechanism of male sterility in Petunia : II. Free amino acids in male fertile and male sterile anthers during microsporogenesis. Quantitative differences in the anther contents of free amino acids were found between fertile and male-sterile petunia lines and between cytoplasmic male-sterile and genic male-sterile lines. The differences between the sterile lines were correla...

Fuchs, J., 1977: On the clinical picture and therapy of arachnitis optico-chiasmatica. From 20 cases of arachnitis optico-chiasmatica (a. o.) the symptoms of this relatively rare but pathologico-anatomically proved disuse of the brain base involving the optic nerves are described. In this description newer methods of investigation a...

Keyserling, H.L.; Sinkowitz-Cochran, R.L.; Harris, J.M.; Levine, G.L.; Siegel, J.D.; Stover, B.H.; Lau, S.A.; Jarvis, W.R., 2003: Vancomycin use in hospitalized pediatric patients. To assess vancomycin utilization at children's hospitals, to determine risk factors for vancomycin use and length of therapy, and to facilitate adapting recommendations to optimize vancomycin prescribing practices in pediatric patients. Two s...

Krishna Jai, 2004: Refinement of time in the Indian geological record; case-sheet of the Jurassic in Kachchh. Journal of the Geological Society of India 63(1): 120-123

Yamazaki, Y.; Chiba, I.; Hirai, A.; Satoh, C.; Sakakibara, N.; Notani, K-ichi.; Iizuka, T.; Totsuka, Y., 2005: Clinical value of genetically diagnosed lymph node micrometastasis for patients with oral squamous cell carcinoma. Background, The purpose of this study was to investigate the incidence and clinical significance of genetically diagnosed lymph node micrometastasis for patients with oral squamous cell carcinoma (SCC).Methods. A total of 495 lymph nodes obtained...

Carreras, E.; Villamor, N.; Reverter, J.C.; Sierra, J.; Grañena, A.; Rozman, C., 1989: Hypertriglyceridemia in bone marrow transplant recipients: another side effect of cyclosporine A. The incidence and duration of hypertriglyceridemia (HTG) associated with allogeneic HLA-identical bone marrow transplantation (BMT) were investigated in 38 patients with normal triglyceride levels (TG) before BMT and without any evidence of prior...

Dold, U., 1972: Experiences with the group examination of bronchial carcinoma patients. Lebensversicherungs Medizin 24(4): 91-94