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Safety of hepatic resection for hepatocellular carcinoma in obese patients with cirrhosis


, : Safety of hepatic resection for hepatocellular carcinoma in obese patients with cirrhosis. Surgery Today 43(11): 1290-1297

This study aimed at investigating the safety of hepatic resection for hepatocellular carcinoma (HCC) in obese patients with cirrhosis in Japan. We reviewed the clinical records of 202 patients with liver cirrhosis, who underwent hepatic resection for HCC between January, 2001 and August, 2011. The patients were divided into three groups according to their body mass index (BMI): the normal body weight (BMI < 24.9 kg/m(2)), obese class I (BMI 25.0-29.9 kg/m(2)), and obese class II (BMI ≥ 30 kg/m(2)) groups. We compared the patient backgrounds, intraoperative factors, and postoperative complications among the three groups. The normal body weight, obese class I, and obese class II groups comprised 138 (68.3 %), 55 (27.2 %), and 9 (4.5 %) patients, respectively. The incidence of non-B non-C cirrhosis was higher in the obese class II group (22 %) than in the normal body weight group (14 %, p = 0.034). Intraoperative blood loss tended to be higher in the obese class II patients than in the other two groups. Postoperative complications and mortality did not differ significantly among the three groups. According to multivariate analysis, obesity was not a risk factor for postoperative complications (Clavien-Dindo classification Grade III or higher) or mortality. Hepatic resection for HCC can be performed safely in obese patients with cirrhosis.

US$19.90

PMID: 23996131

DOI: 10.1007/s00595-013-0706-2


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Managò, F.; Papaleo, F., 2017: Schizophrenia: What's Arc Got to Do with It?. Human studies of schizophrenia are now reporting a previously unidentified genetic convergence on postsynaptic signaling complexes such as the activity-regulated cytoskeletal-associated (Arc) gene. However, because this evidence is still very rece...

Yahata, T.; Kurabayashi, T.; Honda, A.; Tojo, Y.; Tanaka, K.; Abo, T., 1996: Physiological dose of estrogen regulates extrathymic T cells in female mice. Bilateral ovariectomy was performed in female C57BL/6 mice to investigate whether extrathymic T cells in the liver are regulated by physiological doses of estrogen or progesterone. Extrathymic T cells were identified using a two-color immunofluore...

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