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Selection of neighborhood controls for a population-based Lyme disease case-control study by using a commercial marketing database

, : Selection of neighborhood controls for a population-based Lyme disease case-control study by using a commercial marketing database. American Journal of Epidemiology 178(2): 276-279

The selection of controls is an important methodological consideration for case-control studies. Neighborhood-matched control selection is particularly crucial for studies of vector-borne disease, such as Lyme disease, for which risk is intrinsically linked to geographical location. The matching of case-control pairs on neighborhood can help control for variation in ecological risk factors that are tied to geographical location, like vector and host habitat in the peridomestic environment. Random-digit dialing has been used to find neighborhood controls by using the area code and exchange of the case to generate lists of potential control households. An alternative to random-digit dialing is the purchase of residential telephone numbers from a commercial marketing database. This report describes the utility of the (InfoGroup, Papillion, Nebraska) commercial marketing database for neighborhood control recruitment in a Lyme disease case-control study in Connecticut during 2005-2007.


PMID: 23696105

DOI: 10.1093/aje/kws464

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