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Sezary syndrome--without erythroderma

, : Sezary syndrome--without erythroderma. Indian Journal of Dermatology, Venereology and Leprology 68(4): 225-226

Sezary syndrome (SS), is described as the classical triad of pruritic erythroderma, lymphadenopathy, and presence of more than 10% of circulating Sezary cells in the peripheral blood. We report on unusual case of advanced cutaneous T - cell lymphoma with classical haematological and histopathological features of Sezary syndrome, but lacking the clinical features of erythroderma. A 66 year old man presented with asymptomatic multiple papules, plaques and nodules and with generalized lymphadenopathy. Peripheral smear showed more than 60% of Sezary cells. Skin and lymph node biopsy showed typical features of T-cell lymphoma and immunohistochemistry and CD marker studies showed the cells to be atypical T-lymphocytes. This unusual case is highlighted to denote that erythroderma need not be taken as a hard and fast criterion for diagnosing Sezary syndrome.


PMID: 17656944

Other references

Dewannieux, M.; Ribet, D.; Heidmann, T., 2010: Risks linked to endogenous retroviruses for vaccine production: a general overview. Mammalian genomes contain a heavy load of retroelements, which are mobile sequences requiring reverse transcription for their amplification. A significant proportion of these elements is of retroviral origin, with thousands of sequences resembling...

Gracheva, N.M.; Mikhaĭlova, L.M.; Petukhova, V.I.; Davydova, G.K.; Rogova, G.M., 1974: Clinical aspects of Sodoku disease. Sovetskaia Meditsina 37(3): 150-151

Bestwick, C.S.; Brown, I.R.; Bennett, M.H.; Mansfield, J.W., 1997: Localization of hydrogen peroxide accumulation during the hypersensitive reaction of lettuce cells to Pseudomonas syringae pv phaseolicola. The active oxygen species hydrogen peroxide (H2O2) was detected cytochemically by its reaction with cerium chloride to produce electron-dense deposits of cerium perhydroxides. In uninoculated lettuce leaves, H2O2 was typically present within the s...

Popoff, M.R.; Rose, R.; Legardinier, J.C.; Paris, C.; Chauvet, P.; Caziot, F., 1984: Identification of outbreaks of type D botulism among cattle in France. About 200-300 cases of fatal paralysis were recorded in cattle in Brittany and adjacent regions during the past 3 years. Details are given of 11 herds in the Morbihan region where it was necessary to immunize the cattle against Clostridium botulin...

Hubl, H., 1951: Das Verhalten von Regenerationsgewebe nach Implantation in den erwachsenen Organismus bei Lumbriciden. Ein Beitrag zum Geschwulstproblem bei Wirbellosen. Archiv fuer Entwicklungsmechanik der Organismen, 145: 267-292

Sukaryavichus K.A., 1971: Effectiveness of surgical treatment used for traumatic retinal detachment. Oftal'mologicheskii Zhurnal 26(1): 34-39

Berry, A.E., 1927: Viability of pathogenic organisms in butter. The experiments reported in this paper were undertaken to determine the period in which certain pathogenic organisms might survive in butter, and be responsible for disease outbreaks. The general procedure was to inoculate the butter with a broth...

Rodés-Cabau, J.; DeLarochellière, R.; Dumont, E., 2012: First-in-man transcatheter aortic valve implantation of a 20-mm Edwards SAPIEN XT valve: one step forward for the treatment of patients with severe aortic stenosis and small aortic annulus. We present the case of an 85-year-old woman diagnosed with severe aortic stenosis, porcelain aorta, and a small aortic annulus (17.3 mm), who underwent successful transfemoral transcatheter aortic valve implantation (TAVI) with a 20-mm Edwards SAP...

Nuovo, M.A.; Dorfman, H.D.; Sun, C.C.; Chalew, S.A., 1989: Tumor-induced osteomalacia and rickets. Tumor-induced osteomalacia is a clinicopathological entity in which vitamin D-resistant osteomalacia or rickets occurs in association with a tumor. A total of 72 cases (three current, 69 from review of literature) has been reported to date. Men an...

Dow, R.L.; Wright, S.W., 1998: Secondary amines as antidiabetic and antiobesity agents. Official Gazette of the United States Patent & Trademark Office Patents 1211(3): 2934, June 16