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Short-term relative antibacterial effect of octenidine dihydrochloride on the oral microflora in orthodontically treated patients


, : Short-term relative antibacterial effect of octenidine dihydrochloride on the oral microflora in orthodontically treated patients. International Journal of Infectious Diseases 12(6): E19-E25

To evaluate the efficacy of common antiseptic mouth rinses and octenidine dihydrochloride (OCT). The antibacterial activities of antiseptics against total and cariogenic bacteria (Streptococcus mutans and Lactobacillus species) in saliva were studied in vitro and in vivo. After unstimulated saliva was collected, one of the mouth rinse solutions was applied for 30seconds. Saliva samples were collected 15, 30, 60, and 120min later and evaluated for their bacterial count. OCT had a significantly greater inhibitory effect on the studied bacteria than 0.2% chlorhexidine gluconate (CHX) and 7.5% polyvinylpyrrolidone-iodine complex (PVP-I) from 15min to 120min following the application (p<0.01). The antiseptic efficacy of 0.2% CHX on total bacteria and Lactobacillus species was very similar to the efficacy observed with 7.5% PVP-I mouth solution from 15min up to 120min. Streptococcus mutans was completely inhibited by 0.15mg/ml PVP-I, 0.5mg/ml CHX, and 0.1mg/ml OCT concentrations, while Streptococcus salivarius was inhibited by 0.15mg/ml PVP-I, 2mg/ml CHX, and 0.8mg/ml OCT concentrations. Lactococcus lactis subspecies lactis was inhibited with 0.00313mg/ml OCT, 30mg/ml PVP-I, and 0.0063mg/ml CHX concentrations. OCT compared favorably with CHX and PVP-I in its antibacterial effects, both in vitro and in vivo (p<0.01).

US$19.90

PMID: 18538605

DOI: 10.1016/j.ijid.2008.03.013


Other references

Coplen, D.E.; Hare, J.Y.; Zderic, S.A.; Canning, D.A.; Snyderi, H.M.I.; Duckett, J.W., 1996: 10-year experience with prenatal intervention for hydronephrosis. Purpose: We evaluated clinical outcomes after attempted prenatal intervention in fetuses with hydronephrosis. Materials and Methods: We retrospectively reviewed the histories of 10 fetuses considered for prenatal intervention between 1984 and 1993...

Wong, S.L.; Yu, I.T.S.; Wong, T.W.; Lloyd, O.L., 1997: Trends of infant mortality in Hong Kong (1956-90) and evaluation of preventable infant deaths. This study determines the pattern of reliability of infant mortality reports in Hong Kong. Data are obtained from annual reports of the director of Medical and Health Services during 1956-88 and the director of Health during 1989-90. Deaths were g...

Makashvili M.A., 1979: Visual learning and inter hemispheric interaction. Learning of a pattern and light intensity discrimination were studied in 2 groups of cats, 1 group with midline section of the corpus callosum. Acquisition of visual discrimination was significantly prolonged among the corpus callosum sectioned gr...

Drincha, V., 1994: Investigation of working organs for separating seeds by their sphericity. Three devices for separating seeds according to their sphericity are described. They are a centrifugal separator, one in which seeds falling onto and deflected from a curved surface are separated vertically, and one in which seeds falling onto an...

Maeterlinck, Maurice, 1927: Life of the termites. Unlike the felicitous life of the bee, darkness, underground tyranny, cruelty and sordid avarice mark the life of the termite. Such life, however, is crowned by sacrifice to an instinct which causes these unfortunate insects, more than any other l...

Mitov, F., 1977: Mechanical injury to the peritoneum and the formation of postoperative peritoneal adhesions (experimental studies). Khirurgiia 30(5): 399-403

Poy, A.; Minkoulou, E.; Shaba, K.; Yahaya, A.; Gaturuku, P.; Dadja, L.; Okeibunor, J.; Mihigo, R.; Mkanda, P., 2016: Polio Eradication Initiative contribution in strengthening immunization and integrated disease surveillance data management in WHO African region, 2014. The PEI Programme in the WHO African region invested in recruitment of qualified staff in data management, developing data management system and standards operating systems since the revamp of the Polio Eradication Initiative in 1997 to cater for...

Sozay, S.; Bayramoglu, M.; Karatas, M.; Ozker, R., 2002: Diffuse idiopathic skeletal hyperostosis in a patient with idiopathic retroperitoneal fibrosis: a case report. Idiopathic retroperitoneal fibrosis (IRF) is a rare rheumatologic disease with obscure pathogenesis. Its manifestations depend upon the structures involved. Diffuse idiopathic skeletal hyperostosis (DISH) is usually seen in male patients over 45 y...

Omah-Maharaj, I.R., 1991: Serological investigations for Chagas' disease in Trinidad. A total of 512 sera was examined, using the indirect fluorescent antibody test, for antibodies to Trypanosoma cruzi. No positive reactions were detected even for samples from individuals with related cardiac symptoms. These findings suggest that t...

Baptist, B.A., 1976: Beekeeping development programmes in Sri Lanka. Honey production from hunting (Apis dorsata) and beekeeping (Apis cerana) is described. Honey sources are discussed, and the bases for an action programme are set out. Establishment of suitable vegetation areas, bee breeding and bee management, an...