geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Stereotactic radiosurgery for spinal metastases: update on treatment strategies


, : Stereotactic radiosurgery for spinal metastases: update on treatment strategies. Journal of Neurosurgical Sciences 55(3): 197-209

Metastatic tumors are the most common tumors that affect the spinal column and are the source of significant pain and disability in cancer patients. The management of symptomatic spinal metastases presents unique challenges to surgeons as a number of considerations specific to the underlying tumor histology, extent of disease, the functional status of the patient and response to systemic therapy often affect the role, timing and effectiveness of any surgical intervention. As surgical techniques have evolved, the focus of therapy has shifted towards minimizing the morbidity associated with treatments for patients in whom limited nutrition and functional reserve impact their overall survival. As such, stereotactic spinal radiosurgery (SRS) has emerged as a powerful adjunct to surgery as well as a stand-alone treatment option for patients with metastatic disease. Recent technological innovations such as intensity-modulated radiation therapy, image-guidance, and non-invasive spine immobilization have made significant improvements to the delivery of highly conformal radiation to spinal tumors. In this article, current treatment strategies utilizing SRS in the multidisciplinary management of spinal metastases are discussed.

US$29.90

PMID: 21968584


Other references

García-Borboroglu, P.; Boersma, P.Dee.; Ruoppolo, V.; Pinho-da-Silva-Filho, R.; Corrado-Adornes, Aéa.; Conte-Sena, D.; Velozo, R.; Myiaji-Kolesnikovas, C.; Dutra, G.; Maracini, P.; Carvalho-do-Nascimento, Cáudia.; Ramos-Júnior, V.; Barbosa, Lércio.; Serra, S., 2011: Magellanic penguin mortality in 2008 along the SW Atlantic coast. Magellanic penguins migrate from Patagonia reaching northern Argentina, Uruguay, and southern Brazil on their winter migration, in parallel with the seasonal pulse of anchovy spawning. In 2008, Magellanic penguins went further north than usual. Ma...

Jeong, S.W.; Huang, X.Z.; Won, Y.J.; Park, B.G.; Park, K.S.; Kong, I.D.; Lee, J.W., 2003: Modulation of calcium channels by neurotransmitters was altered in primary vagal afferent neurons of vagotomized rats. During many surgical procedures such as heart and lung transplantations, primary vagal afferent fibers can be extensively injured, which may cause significant alterations in functional characteristics of primary vagal afferent neurons (nodose gang...

Juraska, A.; Wood, L.; Giroux, J.; Wood, E., 2015: Sexual assault services coverage on Native American land. Native American women experience higher rates of sexual assault than other women in the United States, yet there is limited information on the accessibility of forensic services for Native American victims of sexual violence. This study used geogr...

O'Keefe, J.A.; Crowley, R.S.; Hrivnak, P.; Kim, N.B.; Amico, J.A., 1995: Effect of testosterone and its metabolites upon the level of vasopressin messenger ribonucleic acid in the hypothalamus of the hyperosmotically stimulated male rat. We previously reported that gonadal steroids modify the expression of arginine vasopressin (AVP) in the hypothalamus of rats administered 2% sodium chloride solution for 5 days. Gonadectomy prevented, and testosterone (T) replacement restored, enh...

Harnacke, P.; Strasser, K.P.; Morgenstern, J., 1976: Influence of lumbar peridural anaesthesia on fetal heart rate patterns in the second stage of labour. The influence of lumbar peridural anaesthesia (PA) on fetal heart rate patterns in the second stage of labour was studied in 218 vaginal deliveries without maternal and fetal risk. A CTG-Score as proposed by Hammacher was used to evaluate fetal he...

Brus, R.; Szkilnik, R.; Felińska, W., 1990: Diazepam (Relanium)--current views on its action with special reference to developmental age. In a survey of the pertinent literature the pharmacological and toxicodynamic, effects, metabolism and mechanism of action of diazepam in experimental animals and humans are discussed. Particular attention is paid to the effects of diazepam given...

Sellwood Bruce W.; Valdes P.J.; Price G.D., 1994: Modelling Jurassic Milankovitch climate variations. Annual Meeting Abstracts - American Association of Petroleum Geologists and Society of Economic Paleontologists and Mineralogists 1994: 255

Kelm, M.; Rath, J.; Pölitz, B.; Strauer, B.E., 1998: Relevance and methods for determining coronary flow reserve. The assessment of coronary flow reserve, defined as the ratio of hyperemic to resting coronary blood flow, allows a more functional analysis of the coronary vasculature in addition to coronary angiography. Three different kinds of cardiac catheriz...

Hong, Mei-Chu, 1995: Studies on the quality of glutinous rice I. Identification of glutinous rice and non-glutinous rice in moisture condition. The present experiment was conducted to discriminate glutinous rice and non-glutinous rice when glutinous rice was sold to Farmers' Association in the form of wet rice. The results of the experiments conducted in the first crop of 1994 are su...

Khazaie, K.; Blatner, N.R.; Khan, M.Wasim.; Gounari, F.; Gounaris, E.; Dennis, K.; Bonertz, A.; Tsai, F-Nien.; Strouch, M.J.; Cheon, E.; Phillips, J.D.; Beckhove, P.; Bentrem, D.J., 2011: The significant role of mast cells in cancer. Mast cells (MC) are a bone marrow-derived, long-lived, heterogeneous cellular population that function both as positive and negative regulators of immune responses. They are arguably the most productive chemical factory in the body and influence o...