geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Surgical resection of malignant melanoma metastatic to the pancreas: case series and review of literature


, : Surgical resection of malignant melanoma metastatic to the pancreas: case series and review of literature. Journal of Gastrointestinal Cancer 43(3): 431-436

Malignant melanoma only rarely metastasizes to the pancreas. As such, there is limited medical literature on the clinical course and outcomes for patients who have undergone surgical management of these tumors. The aim of our study was to review our experience with the surgical resection of melanoma metastatic to the pancreas. The records of five patients (four females, one male) with surgically resected melanoma metastatic to the pancreas were retrospectively reviewed. Tumor characteristics, patient presentation, operative details, and follow-up data were evaluated. The primary site of melanoma was known in three cases and unknown in two cases. Four patients were symptomatic at presentation, including abdominal pain (n = 3), jaundice (n = 2), abdominal distension (n = 1), bleeding metastases (n = 1), and fatigue (n = 1). In one patient, the metastasis was an incidental discovery. Surgical resection was accomplished by pylorus-preserving pancreaticoduodenectomy in four patients and distal pancreatectomy in one patient. Single-site resection was done in two patients while the other three underwent synchronous multiple-site resections. Complications developed post-operatively in three patients. Two patients had progression of disease in the form of new metastatic lesions and received subsequent chemotherapy. The median survival was 11.4 months (range, 3-26 months). Aggressive surgical management of pancreatic metastases provides palliative relief of symptoms and may be considered in appropriately selected candidates.

US$19.90

PMID: 21912850

DOI: 10.1007/s12029-011-9320-y


Other references

Cochin J., 1972: Tolerance to the narcotic analgesics a long term phenomenon. Psychopharmacologia 26(SUPPL): 99

Vallee, P.A., 2011: Symptomatic morgagni hernia misdiagnosed as chilaiditi syndrome. Chilaiditi syndrome, symptomatic interposition of bowel beneath the right hemidiaphragm, is uncommon and usually managed without surgery. Morgagni hernia is an uncommon diaphragmatic hernia that generally requires surgery. In this case a patient w...

Franchi, M.; Babilonti, L.; Tenti, P.; Beretta, P.; L.F.anza, A.; Carnevali, L., 1988: Mixed müllerian malignant tumors of the endometrium (MMMT). Clinico-pathologic study of 14 cases. Annali di Ostetricia, Ginecologia, Medicina Perinatale 109(5): 265-271

Vilches, A.R., 1980: Plasmapheresis and its use in nephrology. Medicina 40(2): 196-202

Worsaae, K.; Müller, M.C.M., 2004: Nephridial and gonoduct distribution patterns in Nerillidae (Annelida: Polychaeta) examined by tubulin staining and cLSM. The distribution and configuration of nephridia and gonoducts are described for seven species from seven genera of the interstitial polychaete family Nerillidae. The ciliated nephridia and gonoducts were identified by tubulin staining and examined...

Wand, H.; Calmy, A.; Carey, D.L.; Samaras, K.; Carr, A.; Law, M.G.; Cooper, D.A.; Emery, S., 2007: Metabolic syndrome, cardiovascular disease and type 2 diabetes mellitus after initiation of antiretroviral therapy in HIV infection. Background: Metabolic syndrome (MS) identifies individuals at risk of cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). Little is known about MS and its consequences following initiation of antiretroviral therapy (ART).Methods: HIV...

Hughes, A.W., 1985: Avulsion fracture involving the body of the patella. A report on an unusual transverse fracture through the body of the patella in a 13 year old high jumper is presented. The clinic features and treatment of the more usual avulsion injury of the patella is discussed.

Schoenwald, S.K.; Chapman, J.E.; Sheidow, A.J.; Carter, R.E., 2009: Long-term youth criminal outcomes in MST transport: the impact of therapist adherence and organizational climate and structure. This study investigated relations among therapist adherence to an evidence-based treatment for youth with serious antisocial behavior (i.e., Multisystemic Therapy), organizational climate and structure, and youth criminal charges on average 4 year...

Tepas, J.J.; Simstein, N.L.; Wagner, W.J.; Mullen, J.T., 1977: The negative appendectomy-a benign misjudgment?. Military Medicine 142(4): 302-303

Manrique, J.; Palao, J.A.; Mesquita, M.B. de, 1993: Andeans unite: the birth and growth of the Andean Council of Ecological Management. The Andean Council of Ecological Management (CAME), is a network of seven NGOs involved in rural development. Its aim is to strengthen the work of individual NGO members who are committed to environmentally sound approaches to agriculture and anim...