+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Surprise! HSC are aberrant in chronic lymphocytic leukemia

, : Surprise! HSC are aberrant in chronic lymphocytic leukemia. Cancer Cell 20(2): 135-136

In this issue of Cancer Cell, Kikushige et al. report the surprising finding that, in human chronic lymphocytic leukemia (CLL), hematopoietic stem cells (HSC) aberrantly generate clonal B cells with CLL-like phenotypes, which implicate HSC in the pathogenesis of this mature lymphoid malignancy and has major implications for CLL therapies.


PMID: 21840478

DOI: 10.1016/j.ccr.2011.08.001

Other references

Shukla, U.C., 1972: Effect of lime, phosphorus and some fertilizer compounds on zinc availability in soils of southern United States. In laboratory studies the effects on the EDTA extractable Zn of samples of highly weathered soils of 4480 kg lime/ha, 280 kg P/ha, 10 ppm Zn, 250 ppm N (as NH4NO3, (NH4)2SO4 or NaNO3) and of 250 ppm K were studied. Lime decreased Zn availability,...

Kanazawa M.; Ishizaka A.; Suzuki Y.; Hasagawa N.; Yokoyama T., 1990: Granulocyte colony stimulating factor induced neutrophilia does not enhance acute lung injury by endotoxin in guinea pigs. American Review of Respiratory Disease 141(4 PART 2): A94

Fuentes Pavon R.; Martinez Lagares F.J.; Marrero Pulido T.; Martinez Islas A.; Rodriguez Rodriguez M., 1988: Description of a new sonographic sign of perforation preliminary report. We describe a sonographic finding, of which we have found no previous reference, that was present in two patients with perforated ulcus and in another patient with known pneumoperitoneum. We think these images are produced by aire in the gastrophe...

Flint, R.W.; Kalke, R.D., 1983: Environmental disturbance and estuarine benthos functioning. Bulletin of Environmental Contamination and Toxicology 31(5): 501-511

Pendyala, G.; Ninemire, C.; Fox, H.S., 2015: Protective role for the disulfide isomerase PDIA3 in methamphetamine neurotoxicity. Methamphetamine abuse continues to be a worldwide problem, damaging the individual user as well as society. Only minimal information exists on molecular changes in the brain that result from methamphetamine administered in patterns typical of huma...

Aranda, S.K.; Kelso, J., 1998: The nurse as coach in care of the dying. Nurses' inability to articulate many aspects of their work leads to its invisibility, a problem compounded in home-based palliative care where the nurse's work is rarely seen by others. A staff development exercise was undertaken which a...

El-Amin, E.; Diab, I.; Ibrahim, S., 2001: Influence of eucalyptus cover on some physical and chemical properties of a soil in Sudan. Irrigated plantations of Eucalyptus microtheca especially under the existing drought, desertification and expansion of agricultural schemes, stand among the very few options left to meet the increasing demand of the society for energy and other fo...

Spitzner, R., 1947: Determination of fluorine in drinking water. For the estimation of F in water, a colorimetric test was used in which the water was treated with a mixed solution of zirconium nitrate and alizarin blue in acid medium, the resulting tint being compared with that obtained with a solution of sodi...

Gonzalez Anssuini, J., 1961: Urine cultures in the Hospital Militar Central (biennial 1959-1960). Their clinical evaluation. Revista de la Sanidad Militar del Peru 34: 11-31

Vargas, S.O.; Grudzien, C.; Tanasejevic, M.J., 1999: Cardiac troponin-I in postmortem serum specimens. Modern Pathology 12(1): 9A, Jan