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Temperature gradients in female reproductive tissues


, : Temperature gradients in female reproductive tissues. Reproductive Biomedicine Online 24(4): 377-380

Deep body temperature in mammals is generally but incorrectly regarded as uniform. Alterations of temperature in oviducts and preovulatory Graafian follicles may play a vital role in gamete maturation, fertilization and early embryonic development. At a molecular level, the conformation of regulatory proteins is susceptible to changes in temperature. Deviation from physiological temperature during IVF procedures could thereby exert a profound influence on patterns of gene expression as the embryonic genome unfolds during early cleavage stages and act to generate specific anomalies. Systematic studies are urgently required. The temperature of internal body organs in mammals such as rabbits and humans is widely regarded as uniform, but this is not correct. Temperatures in reproductive tissues such as ovaries and oviducts vary according to the stage of a menstrual or oestrous cycle. Such changes in temperature are thought to be critically involved in the maturation of eggs and spermatozoa and thus in events shortly before and after fertilization. Proteins in the cytoplasm and nuclei of eggs and very young embryos respond to small shifts in temperature by changing their three-dimensional shape. Conformational modifications in regulatory proteins in the nucleus would influence patterns of gene expression in developing embryos and may, when perturbed, alter the sexual phenotype of an individual. In the practical context of IVF, studies are needed of the influence of culturing gametes and embryos at different temperatures and ranges of temperature on the patterns of gene expression in preimplantation embryos.

US$19.90

PMID: 22369989

DOI: 10.1016/j.rbmo.2011.12.007


Other references

Denson, R.; Stretch, S., 1981: Prevention of smoking in elementary schools. Canadian Journal of Public Health 72(4): 259-263

Allison P.M.; Bang N.U., 1983: The possible role of calcium ii bridges in fibrin polymerization. Thrombosis & Haemostasis 50(1): 356

Laurig, W., 1983: The problem of defining the concept of heavy physical labor. Zentralblatt für Arbeitsmedizin, Arbeitsschutz, Prophylaxe und Ergonomie 33(8): 242-250

Andrikopoulos, A.A.; Box, J.A.; Georgakopoulos, T.A., 1987: Short-run expenditure and price elasticities for agricultural commodities: the case of Greece, 1951-1983. The paper examines consumption patterns of Greek consumers for agricultural and non-agricultural commodities by estimating a complete system of expenditure equations using 1951-83 data. The estimated expenditure and price elasticities of demand sh...

Henseler, K., 1976: Summer weather - mildew weather. Mildew of roses [Sphaerotheca pannosa] develops rapidly when there is a combination of dry weather, high temperatures, bright light for spore formation and free water for spore germination. This combination occurs mostly in high summer with hot br...

Anderson K.E.; Drummond G.S.; Sardana M.K.; Sassa S.; Kappas A., 1979: Effects of exogenous delta amino levulinic acid on liver heme synthesis and degradation in whole animals. Gastroenterology 77(5): A1

Khan, I.M.; Ahmad, A.; Ullah, M.F., 2011: Synthesis, crystal structure, antimicrobial activity and DNA-binding of hydrogen-bonded proton-transfer complex of 2,6-diaminopyridine with picric acid. A proton-transfer (charge transfer) complex formed on the reaction between 2,6-diaminopyridine (donor) and picric acid (acceptor) was synthesized and characterized by FTIR, (1)H NMR, thermal and elemental analysis. The crystal structure determined...

Jacques, T.S.; Skepper, J.N.; Navaratnam, V., 1999: Fibroblast growth factor-1 improves the survival and regeneration of rat vagal preganglionic neurones following axon injury. Adult rat neurones of the dorsal motor nucleus of the vagus (DMNV) react more severely to axon injury than most other peripherally projecting neurones. Following axon injury, DMNV neurones atrophy and die such that after 18 months only 25% remain....

Menezes, P.R.; Lewis, G.; Rasmussen, F.; Zammit, S.; Sipos, A.; Harrison, G.L.; Tynelius, P.; Gunnell, D., 2010: Paternal and maternal ages at conception and risk of bipolar affective disorder in their offspring. A consistent association between paternal age and their offspring's risk of schizophrenia has been observed, with no independent association with maternal age. The relationship of paternal and maternal ages with risk of bipolar affective diso...

Ben Achour, J.; Bouasker, I.; Bedoui, R.; Daghar, K.; Ayari, H.; Guesmi, F.; Aziz Hani, M.; Nouira, R.; Zoghlami, A.; Najah, N., 2009: Myofibroblastic tumor of the great omentum. Myofibroblastic tumors are a spindle cell lesion of indeterminate malignant potential. Abdominal location was rare. We report a case of an unusual location of myofibroblastic tumors in the great omuntum. A 63-year-old women presented with a one ye...