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The complete swine olfactory subgenome: expansion of the olfactory gene repertoire in the pig genome

, : The complete swine olfactory subgenome: expansion of the olfactory gene repertoire in the pig genome. Bmc Genomics 13(): 584-584

Insects and animals can recognize surrounding environments by detecting thousands of chemical odorants. Olfaction is a complicated process that begins in the olfactory epithelium with the specific binding of volatile odorant molecules to dedicated olfactory receptors (ORs). OR proteins are encoded by the largest gene superfamily in the mammalian genome. We report here the whole genome analysis of the olfactory receptor genes of S. scrofa using conserved OR gene specific motifs and known OR protein sequences from diverse species. We identified 1,301 OR related sequences from the S. scrofa genome assembly, Sscrofa10.2, including 1,113 functional OR genes and 188 pseudogenes. OR genes were located in 46 different regions on 16 pig chromosomes. We classified the ORs into 17 families, three Class I and 14 Class II families, and further grouped them into 349 subfamilies. We also identified inter- and intra-chromosomal duplications of OR genes residing on 11 chromosomes. A significant number of pig OR genes (nā€‰=ā€‰212) showed less than 60% amino acid sequence similarity to known OR genes of other species. As the genome assembly Sscrofa10.2 covers 99.9% of the pig genome, our analysis represents an almost complete OR gene repertoire from an individual pig genome. We show that S. scrofa has one of the largest OR repertoires, suggesting an expansion of OR genes in the swine genome. A significant number of unique OR genes in the pig genome may suggest the presence of swine specific olfactory stimulation.


PMID: 23153364

DOI: 10.1186/1471-2164-13-584

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Tokioka H.; Saeki S.; Koyama Y.; Namb T.; Hirakawa M., 1992: The effect of aortic cross clamping on left ventricular filling dynamics during anesthesia of abdominal aortic surgery. Anesthesiology (Hagerstown) 77(3A): A570

Bright, M.; Plum, C.; Riavitz, L.A.; Nikolov, N.; Martinez Arbizu, P.; Cordes, E.E.; Gollner, S., 2011: Epizooic metazoan meiobenthos associated with tubeworm and mussel aggregations from cold seeps of the northern Gulf of Mexico. The abundance and higher taxonomic composition of epizooic metazoan meiobenthic communities associated with mussel and tubeworm aggregations of hydrocarbon seeps at Green Canyon, Atwater Valley, and Alaminos Canyon in depths between 1400 and 2800Ā...

Cox, J.D., 1986: Treatment of cancer of the lung. Wisconsin Medical Journal 85(7): 16-17

Huber R.E., 1973: The effect of transferase activity on the kinetics of honey bee sucrase. Canadian Federation of Biological Societies Proceedings 16: 78

Mollaret, P., 1969: Infections following cat and rat bites. Munchener Medizinische Wochenschrift 111(1): 13-18

Peper J.D. (investigator); Stone B.D. (investigator), 1982: High kames trace fractures in late Wisconsinan ice in southeastern Massachusetts. U S

Blatt, J.; Wollman, M.R.; Albo, V.C.; Orlando, S.; Silverman, C.L., 1984: Recurrent testicular infiltrates following radiation therapy for lymphoid malignancy. From a group of 28 patients with biopsy-proven testicular leukemia seen at our institution since 1979, we describe two boys with lymphoid malignancy who, subsequent to 1,800 rad and 2,400 rad testicular radiation, had second overt testicular relap...

Osbourn, D.F., 1976: Modification of the physical and chemical characteristics of forages and the effects upon intake, digestion and utilization. A review of the possible ways in which modifications can be made in the physical and chemical characteristics of fodders is presented. The influences of fodder characteristics, e.g. cell wall content, resistance to comminution and leafiness, and o...

Rungie, J.M.; Wiskich, J.T., 1973: Salt stimulated atpase from smooth microsomes of turnip. Plant Physiology (Rockville) 51(6): 1064-1068

Momen F.M.; E.B.goury M.E., 1989: A new tydeid mite tydeus longichelus new species from egypt acari tydeidae. A new tydeid mite, Tydeus longichelus is described and illustrated. It was found in soil with roots of the plant Coriandrum at Dokki, Co. Cairo.