geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

The effects of a newly developed miniaturized mechanical chest compressor on outcomes of cardiopulmonary resuscitation in a porcine model*


, : The effects of a newly developed miniaturized mechanical chest compressor on outcomes of cardiopulmonary resuscitation in a porcine model*. Critical Care Medicine 40(11): 3007-3012

When the duration of cardiac arrest is prolonged, reperfusion of the vital organs by effective chest compression is the most important intervention for successful resuscitation. We investigated the effects of a newly developed miniaturized chest compressor on the outcomes of cardiopulmonary resuscitation. Prospective, randomized, controlled experimental study. University-affiliated animal research laboratory. Thirty male domestic pigs. Ventricular fibrillation was induced in 30 male domestic pigs weighing 35 ± 2 kg. Cardiopulmonary resuscitation was initiated after 7 mins of untreated ventricular fibrillation. The animals were randomized to receive mechanical chest compression with a miniaturized chest compressor, a LUCAS device or a Thumper device. After 5 mins of cardiopulmonary resuscitation, a 150-J defibrillation was delivered. If resuscitation was not successful, cardiopulmonary resuscitation was continued for 2 mins before the next defibrillation. The protocol was continued until successful resuscitation or for a total of 15 mins of cardiopulmonary resuscitation. The animals were observed for 72 hrs after resuscitation. The miniaturized chest compressor generated significantly greater coronary perfusion pressure, end-tidal PCO2, carotid blood flow, and intrathoracic negative pressure, with significantly lower compression depth and fewer rib fractures when compared with both the LUCAS and Thumper devices. Both the miniaturized chest compressor and LUCAS devices required lower numbers of defibrillation for successful resuscitation when compared with the Thumper device. This was associated with lower prevalence of recurrent ventricular fibrillation and better postresuscitation myocardial and neurological function when compared with the Thumper device. The miniaturized chest compressor improves hemodynamic efficacy and the success of cardiopulmonary resuscitation with significantly less injury, which is as effective as the LUCAS device. It may provide a new option for cardiopulmonary resuscitation.

US$19.90

PMID: 23080437

DOI: 10.1097/CCM.0b013e31825d924d


Other references

Anonymous, 1986: Life--but what kind of life?. Orvosi Hetilap 127(3): 179-181

Welbank, P.J.; Witts, K.J.; Thorne, G.N., 1968: Effect of radiation and temperature on efficiency of cereal leaves during grain growth. Grain leaf ratio, G (the ratio of grain yield to leaf area duration between ear emergence and maturity), in 15 experiments on wheat and barley in different seasons (Group A experiments) was highly correlated with mean daily radiation, R, mean dail...

Page, R.D.; Yorio, T., 1990: Prostaglandin F2 alpha inhibits acidification in H(+)-secreting epithelia. The role of prostaglandins in the regulation of acidification mechanisms in H(+)-secreting epithelia has been investigated in the abdominal skin of the southern leopard frog, Rana pipiens. Exogenous administration of prostaglandin (PG) E2 and PGF1...

Funk Keenan, J.; Barbato, G.F., 1999: Effect of cool rearing temperature on lines divergently selected for exponential growth rate between 14 and 42 days of age. Poultry Science 78(SUPPL 1): 36

Schutte, Ap, 1976: Infectious diseases of the female affecting calf production. Afrikanerbees joernaal: 22 (1) 35

Mertz, L., 2016: mHealth to the Rescue: Growing use of wireless and mobile technologies improves community health, even in rural areas. NlmCategory="UNASSIGNED">In rural areas, it is not unusual for patients to travel 50 miles or more to reach their doctors? offices or for doctors to refer patients to specialists whose offices are 80, 100, even 200-plus miles away. Th...

Coon, T.M., 2009: Integrating robotic technology into the operating room. Integration of any highly complex technology into the operating room is challenging but can be accomplished with dedicated engineers, trained surgical team members, a streamlined surgical setup, and efficient surgical technique. Early results sugg...

Thorpe, C.; Polanyi, M., 2001: Science against modernism: the relevance of the social theory of Michael Polanyi. Science, as an institution, is widely taken by sociologists to exemplify the modern tendency towards vesting trust and authority in impersonal offices and procedures, rather than in embodied human individuals. Such views of science face an importa...

Ram Singh; Gupta, G.P., 1994: Bioefficacy of systemic insecticides against target pest jassid (Amrasca devastans) and their impact on non-target soil microarthropods in cotton (Gossypium spp.). Field trials were conducted during 1988-89 in New Delhi, India, to study the bioefficacy of spray schedules against Amrasca devastans on cotton and the impact on non-target soil microarthropods. With normal pest populations, phorate (1000 g a.i./h...

Mizota C.; Yoshida N., 1994: Oxygen isotopic constraints on the origin of nodular silica-apatite from the Har Peres pyroclastics, Golan Heights, Israel. Clays and Clay Minerals 42(5): 572-575