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The presence and predictive value of astereognosis and agraphesthesia in patients with Alzheimer's disease


, : The presence and predictive value of astereognosis and agraphesthesia in patients with Alzheimer's disease. Applied Neuropsychology 17(4): 262-266

Sensory and motor functions are good markers of neurocognitive decline due to their proximity and hierarchical relationship to high-order processes. The current study investigated if patients with Alzheimer's disease (AD) differed from a healthy control group in two tactile perceptual processes: astereognosis and agraphesthesia. Analyses were also conducted to see if these tactile processes were predictive of higher-order cognitive functioning. Twenty-eight patients with AD (mean age = 75.86) were compared to 28 healthy control subjects (mean age = 76.38) and were administered the Dean-Woodcock Sensory Motor Battery and the Woodcock-Johnson Psychoeducational Battery-Revised. Results suggest the patients with AD demonstrated significantly higher levels of tactile disturbance and astereognosis while agraphesthesia was able to predict a substantial portion of the variance in 3/7 cognitive tests and 4/7 cognitive tests, respectively. This included measures of fluid reasoning, visual processing, crystallized language, short-term memory, and auditory processing. These results suggest that astereognosis and agraphesthesia may be good markers of the extent of cognitive impairment in AD and should be included in neuropsychological evaluations due to their functional importance.

US$19.90

PMID: 21154039

DOI: 10.1080/09084282.2010.525102


Other references

Kalinowska, M., 2013: Monuments of memory: defensive mechanisms of the collective psyche and their manifestation in the memorialization process. The paper searches for insight in the area of collective memory as a part of collective consciousness, a phenomenon understood as a stabilizing factor for a society's self-image and identity. Collective memories are seen as originating from s...

Bonomi, A.; Bianchi, M.; Benatti, G., 1970: Influence of rations with different contents of animal protein on the health and productivity of meat chickens. In experiments in spring, summer, autumn and winter, a total of 9600 chickens were reared from day-old to 45 days on diets with 8, 4, 2% or no fish meal, then reduced to 5, 3 or 1% or none. Fish meal was the only source of animal protein. Some chi...

Levin, J.I.; Chen, J.M.; Du, M.T.; Nelson, F.C.; Wehr, T.; Dijoseph, J.F.; Killar, L.M.; Skala, S.; Sung, A.; Sharr, M.A.; Roth, C.E.; Jin, G.; Cowling, R.; Di, L.; Sherman, M.; Xu, Z.B.; March, C.J.; Mohler, K.M.; Black, R.A.; Skotnicki, J.S., 2001: The discovery of anthranilic acid-based MMP inhibitors. Part 3: Incorporation of basic amines. Anthranilic acid derivatives bearing basic amines were prepared and evaluated in vitro and in vivo as inhibitors of MMP-1, MMP-9, MMP-13, and TACE. Piperazine 4u has been identified as a potent, selective, orally active inhibitor of MMP-9 and MMP-...

Glukhova L.V.; Sivchikov V.E., 1996: Floral complexes in western Taymyr Permian sediments. Pages 43-52 1996

Mori, M.; Araie, M.; Sakurai, M.; Oshika, T., 1992: Effects of pilocarpine and tropicamide on blood-aqueous barrier permeability in man. The time courses of changes in the effects of topical pilocarpine and tropicamide on the index of the blood-aqueous barrier permeability to plasma protein (Pin) were determined in normal volunteers. Before and after drug instillation in one eye, p...

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McCalmont, T.H., 2012: The mistakable and the unmistakable. Journal of Cutaneous Pathology 39(2): 222-224

Sattler, H., 1965: The effect of some wood properties on the manufacture of cement-bound woodwool building slabs. In slabs made from Pinus sylvestris (a) sound and (b) bluestained, Betula verrucosa (c), or Populus nigra (d), final bending strengths after 28 days were equal for (a) and (d), 20-30% less for (c), and 37% less for (b). The inhibiting effect on ce...

Gundel, J.; Herman, I.; Szelenyine, G.M.; Acs, T.; Regiusne, M.A.; Borosne, G.A.; Lugasi, A.; Csapo, J.; Szabo, P.; Bodo, I., 2005: Effects of feeding on the production of Hungarian Large White x Hungarian Landrace and Mangalitsa (Blonde). 1st Paper: Effects on fattening performance and slaughter quality slaughtering in different live weight. The performance and quality of meat products of growing-finishing Hungarian Large White (HLW) x Hungarian Landrace (HL) and Blond Mangalitsa were studied. Animals were fed according to a three-phase nutritional method with different compound feeds...

Smalley I.J.; Unwin D.J., 1975: The formation and shape of drumlins and their distribution and orientation in drumlin fields. 21: 176-189 1975