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The role of FOXP3 in disease progression in colorectal cancer patients


, : The role of FOXP3 in disease progression in colorectal cancer patients. Oncoimmunology 2(6): E24521-E24521

The transcription factor forkhead box P3 (FOXP3) has been identified as a marker of CD4+CD25+ regulatory T cells and is a key determinant of their immunosuppressive functions. FOXP3 has indeed been shown to limit antitumor immune responses during tumor progression. In addition, by expressing FOXP3, tumor cells may evade effector T-cell responses.

US$19.90

PMID: 23894712

DOI: 10.4161/onci.24521


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