geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Ulcerative jejunitis in a child with celiac disease


, : Ulcerative jejunitis in a child with celiac disease. Bmc Gastroenterology 14(): 29-29

Celiac disease can present in children and adults with a variety of manifestations including a rare complication known as ulcerative jejunitis. The latter has been associated with refractory celiac disease in adult onset patients. The objective of this case report is to describe the first pediatric case of ulcerative jejunitis in celiac disease, diagnosed by capsule endoscopy, which was not associated with refractory celiac disease. The 9 year old girl presented with a history of abdominal pain and vomiting. Laboratory investigations revealed a slightly elevated IgA tissue transglutaminase antibody level in the setting of serum IgA deficiency. Initial upper endoscopy with biopsies was not conclusive for celiac disease. Further investigations included positive IgA anti-endomysium antibody, and positive HLA DQ2 typing. Video capsule endoscopy showed delayed appearance of villi until the proximal to mid jejunum and jejunal mucosal ulcerations. Push enteroscopy with biopsies subsequently confirmed the diagnosis of celiac disease and ulcerative jejunitis. Immunohistochemical studies of the intraepithelial lymphocytes and PCR amplification revealed surface expression of CD3 and CD8 and oligoclonal T cell populations. A repeat capsule study and upper endoscopy, 1 year and 4 years following a strict gluten free diet showed endoscopic and histological normalization of the small bowel. Ulcerative jejunitis in association with celiac disease has never previously been described in children. Capsule endoscopy was essential to both the diagnosis of celiac disease and its associated ulcerative jejunitis. The repeat capsule endoscopy findings, one year following institution of a gluten free diet, also suggest that ulcerative jejunitis is not always associated with refractory celiac disease and does not necessarily dictate a poor outcome.

US$19.90

PMID: 24524552

DOI: 10.1186/1471-230X-14-29


Other references

Galíndez, J.; Soriano, V.; González-Lahoz, J., 1994: AIDS in the elderly. Revista Clinica Espanola 194(2): 138-139

Pace, R., 2004: Hygronomini and Athetini from China Coleoptera, Staphylinidae with notes on the synonymy Hygronomini e Athetini della Cina con note sinonimiche Coleoptera, Staphylinidae. The tribe Athetini is represented by a large number of species in all zoogeographical regions. The taxonomy of this group is rather difficult and relies heavily on the characters of the male copulatory organ and of female spermatheca. In the prese...

Hutchinson, Jd, 1983: Farm budgets, economic potential and modern technology New Zealand. New Zealand agricultural science 17(1): 226-230

Hanski E.J.; Pankka H.S.; Walker R.J., 1995: The Nuttio serpentinite belt, central Lapland; a new example of Palaeoproterozoic ophiolitic mantle rocks in Finland. Pages 62 1995

Clérouin, J.; Robert, G.; Arnault, P.; Kress, J.D.; Collins, L.A., 2013: Behavior of the coupling parameter under isochoric heating in a high-Z plasma. The ion-ion coupling parameter Γ is estimated for tungsten along the ρ=40 g/cm(3) isochore corresponding to twice the normal density with temperatures ranging from 10 eV to 5 keV. Using a variety of approaches from a spherical Thomas-Fermi ion t...

Berglin, L.; Crafoord, S.; Stenkula, S.; Kvanta, A.; Seregard, S., 2000: Visual outcome is better in younger patients after surgical removal of choroidal neovascular membranes. Acta Ophthalmologica Scandinavica 78(3): 312, June

Jiao Yangquan; L.Z.en; Zhou Haimin, 1998: The integrated study of sediment sources in sedimentary basins; an example from the Eogene Nanpu Depression, eastern Hebei, China. The conventional heavy mineral techniques are effective tools for determining provenance orientations and properties of parent rocks, but there exist limitations because: (1) it is difficult to discriminate the source areas of limestones, doloston...

Hindle, W.H., 1994: The diagnostic evaluation. Breast symptoms are appropriately evaluated by a breast-oriented history and by the diagnostic triad of clinical breast examination, FNA, and mammography. In the case of a palpable dominant mass, concordance of the diagnostic triad yields a reliab...

Hossain, M.; Imanishi, S.; Matsumoto, A., 1994: Production of somatic hybrids between tomato (Lycopersicon esculentum) and night shade (Solanum lycopersicoides) by electrofusion. Fertile tetraploid somatic hybrids were produced by electrofusing mesophyll protoplasts of tomato cv. Ohgata Zuiko and Solanum lycopersicoides. Following electrofusion the protoplasts were plated in modified TM2 medium in which S. lycopersicoides...

Velasco, R.; Varela, G., 1963: Pullulation Of Rickettsia Ricketsii In Rats Infected By Intraperitoneal Injections Of Blood. Revista del Instituto de Salubridad Y Enfermedades Tropicales 23: 39-43