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Use of intravenous fluids in Hong Kong children hospitalised for diarrhoea and relationship to severity and aetiology

, : Use of intravenous fluids in Hong Kong children hospitalised for diarrhoea and relationship to severity and aetiology. Vaccine 27 Suppl 5: F55-F60

This study assessed the clinical management and impact of diarrhoea aetiology (rotavirus positive/negative) and rotavirus genotype on diarrhoeal disease severity. Of 7391 diarrhoea admissions less than 5 years of age over a 2-year period, 80% of patients were tested for rotavirus, 87% were cultured for bacterial pathogens and 78% were assessed for both. Diarrhoeal severity scores were greatest in those children with mixed rotavirus and bacterial infections. Between 1.3 and 8.4% of infants were considered dehydrated yet intravenous fluids were used for 48% of infants (69% rotavirus positive, 72% mixed infection). These findings support the promotion of oral rehydration therapy over intravenous fluids.


PMID: 19931721

DOI: 10.1016/j.vaccine.2009.08.062

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