geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Vitamin B6 deficiency and diseases in elderly people--a study in nursing homes


, : Vitamin B6 deficiency and diseases in elderly people--a study in nursing homes. Bmc Geriatrics 13(): 13-13

Vitamin deficiency is a cause of health related problems in elderly people. The aims were to study associations between vitamin B6 (B6) and diseases (primarily functional gastrointestinal disorders) in elderly people in nursing homes, the prevalence of B6 deficiency and factors associated with B6 deficiency.This cross-sectional study included residents in nursing homes. Demographics, nutritional status (Mini Nutritional Assessment, MNA ), physical activity, activity of daily living (Katz Index), dietary habits, use of drugs, and psychiatric and somatic diseases were recorded. A blood sample was collected for haematological and biochemical screening, including B6 (p-PLP); p-PLP values < 20 nmol/l indicates B6 deficiency. The results are given as mean (SD).Sixty-one residents (men/women: 22/39) with an age of 85.3 (6.8) years and BMI 25.7 (4.5) kg/m2 were included. Malnutrition and risk of malnutrition were present in 11.5% and 61% respectively. Dietary intake of B6 (mg/day) in men and women were 1.60 (0.30) and 1.18 (0.31) (recommended 1.6 and 1.2 respectively), and 14 (23%) used B6 supplements. Median p-PLP was 20.7 (range <4.0-175.8), 30 subjects (49%) had B6 deficiency. B6 deficiency was associated with old age, low s-alanine aminotransferase and s-albumin, elevated s-homocysteine and inactivity (p-values 0.01-0.03). There were no clinically significant associations between B6 deficiency and somatic or psychiatric disorders, and B6 deficiency was not observed in subjects given B6 supplements.Half of the residents had vitamin B6 deficiency. Vitamin supplement was effective prophylaxis for deficiency and should be recommended to all elderly people in nursing homes.

US$19.90

PMID: 23394203

DOI: 10.1186/1471-2318-13-13


Other references

Nakao K.; Kagawa S.; Murakoso K.; Hata M.; Matsuoka A., 1980: Insulin receptors in rabbit erythrocytes. The existence of insulin receptors in rabbit erythrocytes was studied by evaluating the specific binding of 125I-insulin to erythrocyte membranes. The binding of 125I-insulin was pH-, time- and temperature-dependent. Maximal binding was achieved b...

Wang, H.; Wen, S.; Bunnett, N., W.; Leduc, R.; Hollenberg, M., D.; Macnaughton, W., K., 2008: Proteinase-activated receptor-2 induces cyclooxygenase-2 expression through beta-catenin and cyclic AMP-response element-binding protein. Chronic inflammation of mucosae is associated with an increased cancer risk. Tumorigenesis in these tissues is associated with the activity of some proteinases, cyclooxygenase-2 (COX-2), and beta-catenin. Serine proteinases participate in both inf...

Rhodes Amy Larson; Oreskes Naomi, 1996: Magnetite deposits at El Laco, Chile; a transition between magmatic and epithermal processes or all hydrothermal?. Abstracts with Programs - Geological Society of America 28(7): 335

Evans T.J.; Cohen J., 1992: Immunotherapy of infectious diseases british hellenic scandanavian societies of chemotherapy. Journal of Antimicrobial Chemotherapy 29(5): 495-498

Marcucci F.; Garbagna L.; Monti F.; Bonazzi P.; Canobbio L.; Zuccato E.; Mussini E., 1980: Gas chromatographic determination of 2 fluorinated benzodiazepines in rats and mice. Journal of Chromatography 198(2): 180-184

Rosell, S.; Rosen, A., 1961: The functional state of vasomotor nerves to skeletal muscle vessels in reserpinized cats. The functional state of vasomotor nerves to skeletal muscle vessels was studied in anesthetized cats treated with reserpine. The effects of the vasoconstrictor nerves could be completely blocked by reserpine while the responses of the vasodilator...

Gottsegen, G.; Romoda, T., 1958: Unconsciousness during coughing. Orvosi Hetilap 99(50): 1742-1744

Taylor, A.H.; Miller, R.; Gray, R.D., 2013: Reply to Boogert et al.: The devil is unlikely to be in association or distraction. Proceedings of the National Academy of Sciences of the United States of America 110(4): E274-E274

Gillette S.M.; Gillette E.L.; Shida T.; Boon J.; Miller C.W.; Powers B.E., 1992: Late radiation response of canine mediastinal tissues. The mediastinal tissues which included heart, lung, trachea and esophagus of 70 adult beagle dogs were irradiated to a range of total radiation doses between 24 and 68 Gy given in 2, 3 and 4 Gy fractions. The purpose of the study was the calculati...

Boudjema A.; Hamel M.; Mohamedi A.; Lounissi R., 1990: Petroleum potential of the Reggane Basin, Algeria. AAPG Bulletin: , Pages 616. 1990.