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Vitamin D status and Parkinson's disease: a systematic review and meta-analysis

, : Vitamin D status and Parkinson's disease: a systematic review and meta-analysis. Neurological Sciences 35(11): 1723-1730

To estimate the associations between vitamin D status and Parkinson's disease (PD). We searched electronic databases of the human literature in PubMed, EMBASE and the Cochrane Library up to February, 2014 using the following keywords: 'vitamin D' or '25(OH)D' and 'status' or 'deficiency' or 'insufficiency' and 'Parkinson's disease'. A systematic review and meta-analysis were conducted on observational studies that reported the association between blood vitamin D levels and PD. Seven studies met the inclusion criteria. 1,008 patients and 4,536 controls were included. Results of our meta-analysis show that PD patients had lower mean levels of 25-hydroxyvitamin D [25(OH)D] than healthy controls [weighted mean difference (MD), -16.9, 95 % confidence interval (CI)], -33.5 to -0.2). Patients with vitamin D insufficiency [25(OH)D level <75 nmol/l] had an increased risk of PD (OR 1.5, 95 % CI 1.1-2.0). Patients with vitamin D deficiency [25(OH)D level <50 nmol/l] experienced a twofold increased risk of PD (OR 2.2, 95 % CI 1.5-3.4). Low vitamin D levels are associated with an increased risk of PD.


PMID: 24847960

DOI: 10.1007/s10072-014-1821-6

Other references

Migie, H., 1979: Changes in costs of food processing, distribution, and retailing and their impact on the food system. Proceedings of the Canadian Agricultural Outlook Conference: 58-66

Bolas, B.D., 1926: Methods for the study of assimilation and respiration in closed systems. An apparatus is devised for the preparation of CO2 mixtures and their circulation in a closed system containing a living plant. The system includes a simple mercury pump having glass ball valves, working without grease and avoiding the risk of lea...

Phillips, T.E.; Cornejo, C.J.; Hoffer, E.K.; McCormick, W.C., 2005: Gastrostomy and jejunostomy placement: the urban hospital perspective pertinent to nursing home care. In nursing home settings, providers often think that most percutaneous endoscopic gastrostomy (PEG) tubes are placed in older people, some perhaps inappropriately. We sought to describe the relationships between patient age and the indications for...

Klemen, U.M., 1976: Urgent keratoplasty in actinomycosis of the cornea. The case is reported of a 41-yr-old man with Actinomyces sp. infection of the right eye. Treatment with antibiotics was unsuccessful. The condition was cured by perforating keratoplasty.

Aharony, D.; Dobson, PT.; Krell, RD., 1985: In vitro metabolism of (3H)-peptide leukotrienes in human and ferret lung: a comparison with the guinea pig. Fragmented lung tissue prepared from human, ferret and guinea pig converted 3H -leukotriene C4 ( 3H -LTC4) to 3H -LTD4 and 3H -LTE4. 3H -LTD4 was the major product recovered from incubations with human and guinea pig lung, whereas 3H -LTE4 was the...

Arisawa, M.; Tanii, S.; Tazawa, T.; Yamaguchi, M., 2016: Rhodium-catalyzed transformation of heteroaryl aryl ethers into heteroaryl fluorides. NlmCategory="UNASSIGNED">A rhodium complex catalyzed the conversion of the C-O bond of heteroaryl aryl ethers to the C-F bond. The reaction of (4-chlorophenylthio)pentafluorobenzene with heteroaryl aryl ethers provided heteroaryl fluo...

Placek, P.J.; Taffel, S.M., 1988: Recent patterns in cesarean delivery in the United States. The United States cesarean rate has risen from 5.5 per 100 deliveries in 1970 to 24.1 per 100 deliveries in 1986 according to the National Hospital Discharge Survey. Less than 10 per cent of mothers have a vaginal birth after a prior cesarean. Wom...

Foster M.S.; Srivastava L.S.; Knowles H.C.Jr; Perisutti G., 1977: Menstrual dys function in juvenile diabetes. Diabetes 26(SUPPL 1): 397

Wallace, F.G.; Wagner, M.; Rogers, W.E., 1973: Varying kinetoplast ultrastructure in two subspecies of Herpetomonas muscarum (Leidy). The ultrastructure of the kinetoplasts of Herpetomonas muscarum muscarum, a Trypanosomatid flagellate from Musca domestica L., and H. m. ingenoplastis, from Phormia regina (Mg.), are described from studies with the electron microscope.

Herath P.R.J.; Davidson G., 1981: The nature of malathion resistance in a population of anopheles culicifacies. Malathion resistance in a population of A. culicifacies from Maharashtra State, India, which also showed resistance to a number of other organophosphorus compounds, was dominant in its expression. Most of the crossing and back-crossing results inv...