+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

An estimation for an appropriate end time for an intraoperative intravenous lidocaine infusion in bowel surgery: a comparative meta-analysis

, : An estimation for an appropriate end time for an intraoperative intravenous lidocaine infusion in bowel surgery: a comparative meta-analysis. Journal of Clinical Anesthesia 28(): 95-104

There exists no commonly accepted regimen for an intravenous lidocaine infusion (IVLI). This study aims to determine an appropriate end time for an IVLI during bowel surgery. A systematic search for randomized controlled trials assessing IVLI for bowel surgery was conducted using Ovid MEDLINE, EMBASE, CINAHL, Cochrane CENTRAL, Google Scholar, hand-searching references, and grey literature. Data were pooled for studies that stopped IVLI ≤60 minutes (intraoperative IVLI) after skin closure and where IVLI continued >60 minutes after surgery (postoperative continued IVLI). Quantitative analysis was done using the random-effects model. Seven studies (n = 362) were identified after the systematic search. Three studies (n = 160) and 4 studies (n = 202) used an intraoperative and postoperative continued IVLI, respectively. An intraoperative IVLI significantly reduced pain scores at rest for 48 hours (standardized mean difference on a 0-10 scale, -1.24; 95% confidence interval, -1.93 to -0.56) and 72 hours (standardized mean difference, -1.12; 95% confidence interval, -1.79 to -0.44) compared with postoperative IVLI (test for interaction: P < .001 and P = .003, respectively). Although intraoperative IVLI reduced 24-hour pain scores on movement, this was not statistically different than pain scores in the postoperative IVLI group (test of interaction: P = 0.68). There were no differences between intraoperative IVLI and postoperative IVLI for postoperative in-hospital nausea, vomiting, time to bowel movement, and length of hospital stay. Continuing an IVLI beyond 60 minutes after surgery has no added analgesic or gastrointestinal benefit. Further research is needed to clarify an optimal IVLI regimen and end time.


PMID: 26342631

DOI: 10.1016/j.jclinane.2015.07.007

Other references

Ouf, S.A., 1993: Mycoflora and population dynamics of some seedborne fungi in relation to the fungicide Benlate. A total of 1478 and 1108 fungal isolates were associated to one gram seeds of Convolvulus arvensis and Rumex dentatus respectively. The dominant genera were Aspergillus and Penicillium followed by Paecilomyces, Rhizopus and Fusarium. Aspergillus n...

Hedayati, A.; Safahieh, A., 2012: Serum hormone and biochemical activity as biomarkers of mercury toxicity in the yellowfin seabream Acanthopagrus latus. This study was undertaken in two separate environmental and experimental conditions. The environmental test was carried out at creeks in the Persian Gulf and the experimental test was undertaken in seawater re-circulatory tanks. Mercury concentrat...

Foster, L.B.; Frings, C.S., 1970: Determination of diazepam (valium) concentrations in serum by gas-liquid chromatography. Clinical Chemistry 16(3): 177-179

Fossa-Mancini, E., 1919: Sulla structura della corona di alcuni Ananchytidae e sulla posizione del genere Ananchothuria. Rivista Italiana di Paleontologia, 25: 59-73

Respondek, M.; Buts, L.; D.J.nge, N.; Haesaerts, S.; Loris, R.; Van Melderen, L.; Wyns, L.; Zangger, K., 2009: Sequence-specific 1H, 15N and 13C resonance assignments of the 23.7-kDa homodimeric toxin CcdB from Vibrio fischeri. CcdB is the toxic component of a bacterial toxin-antitoxin system. It inhibits DNA gyrase (a type II topoisomerase), and its toxicity can be neutralized by binding of its antitoxin CcdA. Here we report the sequential backbone and sidechain (1)H, (...

Tzourio, C.; Levy, C.; Dufouil, C.; Touboul,; Ducimetiere, P.; Alperovitch, A., 2001: Low cerebral blood flow velocity and risk of white matter hyperintensities. Cerebral blood flow velocity (CBF-V) measured by transcranial doppler was assessed in 628 elderly individuals who had cerebral magnetic resonance imaging performed as part of a population-based study on vascular aging. Cerebral white matter hyperi...

Stockl, J.P., 1990: FELIX - a branch-oriented planning and control information system. FELIX is a flexible cost-accounting software package that has been continuously developed over the last 4 yr at Weihenstephan, Germany, and is now widely applied in the food industry. It can be used for planning and simulation as an aid to decisio...

Anonymous, 1958: PHYSICAL changes in the prolapsed disc. Lancet 1(7032): 1214-1215

Winkler J.T., 1982: The hydromedusae of the amsterdam mid north atlantic plankton expedition 1980 coelenterata hydrozoa. A faunistic description is given of the hydromedusae collected during the 1980 Amsterdam Mid North Atlantic Plankton Expedition. In all, 30 spp. were caught during the sampling period April 11-May 2, 1980. Remarks are made on structural details of...

D.A.genio B.; Fischer A.G.; Richter G.M.; Longo G.; Pelosi N.; Molisso F.; Duarte Morais M.L., 1998: Orbital cyclicity in the Eocene of Angola; visual and image-time-series analysis compared. Photographic coverage of hemipelagic Eocene marls of Angola (Africa), supplemented by limited sampling, shows rhythmic stratification patterns of two types: (a) hierarchically cyclic variation in calcium carbonate/clay ratios forming couplets grou...