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Antioxidant activity of a new phenolic glycoside from Lagenaria siceraria Stand. fruits

, : Antioxidant activity of a new phenolic glycoside from Lagenaria siceraria Stand. fruits. Food Chemistry 132(1): 244-251

The antioxidant properties of different extracts of Lagenaria siceraria (bottle gourd) fruit were evaluated. In the process, a new phenolic glycoside (E)-4-hydroxymethyl-phenyl-6-O-caffeoyl-β-d-glucopyranoside (1) was isolated and identified together with 1-(2-hydroxy-4-hydroxymethyl)-phenyl-6-O-caffeoyl-β-d-gluco-pyranoside (2), protocatechuic acid (3), gallic acid (4), caffeic acid (5) and 3,4-dimethoxy cinnamic acid (6). Their structures were elucidated by extensive NMR experiments including (1)H-(1)H (COSY) and (1)H-(13)C (HMQC and HMBC) spectroscopy and chemical evidences. The antioxidant potential of the compound 1 and 2 was tested in different in vitro assay systems such as free radical scavenging assay, 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction assay, superoxide scavenging activity, reducing power assay and linoleic acid peroxidation assay.


PMID: 26434287

DOI: 10.1016/j.foodchem.2011.10.063

Other references

Ertl, B.; D.B.eecker, L.; Engel, A.G., 1994: Similarities and differences between target formations and the lesions in desmin storage myopathy. Neurology 44(4 SUPPL 2): A197

Hertogen J.; Vanlerberghe L.; Namegabe M.R., 1985: Geochemical evolution of the Nyiragongo Volcano (Virunga, Western Africa Rift, Zaire). Bulletin of the Geological Society of Finland 57(1-2): 21-35

Bergan, T.; Lystad, A., 1972: Reproducibility in bacteriophage sensitivity pattern of Pseudomonas aeruginosa. Acta Pathologica et Microbiologica Scandinavica. Section B: Microbiology and Immunology 80(3): 345-350

Desai, H.G., 1965: Complete heart block with recent myocardial infarction. Value of steroid therapy. Indian Journal of Medical Sciences 19(11): 811-817

Chu, K.C.; Smart, C.R.; Tarone, R.E., 1988: Analysis of breast cancer mortality and stage distribution by age for the Health Insurance Plan clinical trial. The Health Insurance Plan (HIP) of Greater New York conducted a clinical trial to determine if screening for breast cancer with mammography and clinical examination would decrease breast cancer mortality. The extent of disease at diagnosis among b...

Arp, L.H.; Grier, R.L., 1984: Disseminated cutaneous hemangiosarcoma in a young dog. Disseminated cutaneous haemangiosarcoma was diagnosed in a 1-year-old dog despite the benign histological appearance of most tumour foci. An initial, raised, 3-cm diameter, erythematous skin lesion over the left tarsus expanded over a 6-week perio...

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Maganto Pavón, E.; de Tamayo, A., 1993: Urologic specialization of the Bachelor Andrés de Tamayo, famous surgeon and writer of the 17th century. During the second half of the 15th century and beginning of the 16th century, the problem of "carnosities" and "urine passion" aroused an enormous concern within the social and courtesan environments. The Monarchy, participatin...

Vaz, AH.; Brownson, EA.; Blomquist, GJ.; Reitz, RC., 1989: Sex pheromone biosynthesis in the housefly: evidence for the regulation of the fatty acyl-CoA desaturation and elongation system by 20-hydroxyecdysone. The effects of age, sex and 20-hydroxyecdysone [ecdysterone] treatments on fatty acyl-CoA desaturation and elongation, key reactions in sex pheromone biosynthesis in Musca domestica, were investigated. Radio-HPLC analyses of the elongation product...

Sawyer, D., 2008: Climate change, biofuels and eco-social impacts in the Brazilian Amazon and Cerrado. While global technical progress is relatively linear, there is wide variation in its environmental and social impacts at the local level, with cycles of expansion and retraction or boom and bust, of long or short duration. Analysis of previous op...