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Association of Mental Disorders With Subsequent Chronic Physical Conditions: World Mental Health Surveys From 17 Countries


, : Association of Mental Disorders With Subsequent Chronic Physical Conditions: World Mental Health Surveys From 17 Countries. JAMA Psychiatry 73(2): 150-158

It is clear that mental disorders in treatment settings are associated with a higher incidence of chronic physical conditions, but whether this is true of mental disorders in the community, and how generalized (across a range of physical health outcomes) these associations are, is less clear. This information has important implications for mental health care and the primary prevention of chronic physical disease. To investigate associations of 16 temporally prior DSM-IV mental disorders with the subsequent onset or diagnosis of 10 chronic physical conditions. Eighteen face-to-face, cross-sectional household surveys of community-dwelling adults were conducted in 17 countries (47,609 individuals; 2,032,942 person-years) from January 1, 2001, to December 31, 2011. The Composite International Diagnostic Interview was used to retrospectively assess the lifetime prevalence and age at onset of DSM-IV-identified mental disorders. Data analysis was performed from January 3, 2012, to September 30, 2015. Lifetime history of physical conditions was ascertained via self-report of physician's diagnosis and year of onset or diagnosis. Survival analyses estimated the associations of temporally prior first onset of mental disorders with subsequent onset or diagnosis of physical conditions. Most associations between 16 mental disorders and subsequent onset or diagnosis of 10 physical conditions were statistically significant, with odds ratios (ORs) (95% CIs) ranging from 1.2 (1.0-1.5) to 3.6 (2.0-6.6). The associations were attenuated after adjustment for mental disorder comorbidity, but mood, anxiety, substance use, and impulse control disorders remained significantly associated with onset of between 7 and all 10 of the physical conditions (ORs [95% CIs] from 1.2 [1.1-1.3] to 2.0 [1.4-2.8]). An increasing number of mental disorders experienced over the life course was significantly associated with increasing odds of onset or diagnosis of all 10 types of physical conditions, with ORs (95% CIs) for 1 mental disorder ranging from 1.3 (1.1-1.6) to 1.8 (1.4-2.2) and ORs (95% CIs) for 5 or more mental disorders ranging from 1.9 (1.4-2.7) to 4.0 (2.5-6.5). In population-attributable risk estimates, specific mental disorders were associated with 1.5% to 13.3% of physical condition onsets. These findings suggest that mental disorders of all kinds are associated with an increased risk of onset of a wide range of chronic physical conditions. Current efforts to improve the physical health of individuals with mental disorders may be too narrowly focused on the small group with the most severe mental disorders. Interventions aimed at the primary prevention of chronic physical diseases should optimally be integrated into treatment of all mental disorders in primary and secondary care from early in the disorder course.

US$19.90

PMID: 26719969

DOI: 10.1001/jamapsychiatry.2015.2688


Other references

Glasebrook A.L.; Tovey J.A.; Chiller J.M., 1987: Induction of t cell unresponsiveness by calcium ionophore. Federation Proceedings 46(3): 457

Weitzman, E.D.; Dominguez, J., 1963: A Behavioral Method For The Study Of Aversive Stimuli In The Monkey: The Effects Of Parietal Cortical Ablations. Transactions of the American Neurological Association 88: 287-290

Stolarska, M.A.; Kim, Y.; Othmer, H.G., 2009: Multi-scale models of cell and tissue dynamics. Cell and tissue movement are essential processes at various stages in the life cycle of most organisms. The early development of multi-cellular organisms involves individual and collective cell movement; leukocytes must migrate towards sites of in...

Koburger, J.; Rodgers, M., 1979: Effect of glucose concentration on recovery of fungi from foods. Journal of food protection 42(3): 249-250

Favila, A.; Gallo, M.; Glossman-Mitnik, D., 2007: CHIH-DFT determination of the molecular structure infrared spectra, UV spectra and chemical reactivity of three antitubercular compounds: Rifampicin, Isoniazid and Pyrazinamide. Three of the most frequent antitubercular agents employed against Mycobacterium tuberculosis are: Rifampicin, Isoniazid and Pyrazinamide. It has been proven that the use of these antitubercular agents together, shortens the treatment period from 1...

Hwang, S.R.; Chen, T.Y., 1992: Cement bonded wood particleboards - (I) Setting properties of the cement mixed with wood particles. The main purpose of this study was to examine the compatibility of different wood species particles with portland cement by setting time and compressive strength test. The species tested were: Taiwania cryptomerioides, Cryptomeria japonica, Cunnin...

Gaemers P.A.M.; Vorren T.O., 1985: Otolith stratigraphy of late weichselian and holocene sediments of malangsdjupet off northern norway. Otoliths of eleven fish species have been identified in cores recovered from the trough Malangsdjupet (close to 70.degree. N) on the Norwegian continental shelf. The codfish family (Gadidae) dominates with eight species. Three acme-zones belonging...

Schoenfeld H., 1985: Antibiotics and chemotherapy vol 33 prevention of perioperative infections. This book discusses the controversial topic of use of antibiotics to prevent perioperative infection. Each paper discusses a certain operative site in terms of risks, needs, benefits, and costs of use of chemoprophylaxis. There are nine chapters o...

Yoshida, K., 1982: The effects of heat and air-conditioning on the patient. Japanese Journal of Nursing 34(9): 15-22

Adachi, S.; Kono, M.; Takada, Y.; Ohbayashi, K.; Monzawa, S.; Hamanaka, A.; Uotani, K.; Sugimura, K.; Kadoh, T.; Kotani, Y.; Sakamoto, S.; Senda, M., 2003: Diagnostic imaging--recent progress. Current advances in the diagnostic imaging for lung cancer includes multidetector-row CT (MDCT), lung cancer screening using low-dose MDCT and fluorodeoxyglucose positron emission tomography (FDG-PET) imaging. There is no question about the clinic...