geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

BLCA1 expression is associated with angiogenesis of bladder cancer and is correlated with common pro-angiogenic factors


, : BLCA1 expression is associated with angiogenesis of bladder cancer and is correlated with common pro-angiogenic factors. International Journal of Clinical and Experimental Medicine 8(9): 16259-16265

To study the association between expression of BLCA1 and clinicopathological parameters of bladder cancer. Seventy-seven bladder cancer tissue samples were collected and primary antibody of BLCA1 was generated via animal inoculation. Immunohistochemical staining of BLCA1 and several pro-angiogenic factors were performed and evaluated semi-quantitatively. Statistical analyses were used to reveal the associations therein. Expression of BLCA-1 was not associated with tumor characteristics such as occurrence, size, or onset pattern, but was associated with progression of tumor grade, stage, and with muscle invasion. BLCA1 expression was correlated with expression of VEGF, MMP9, IL1α, IL8, and microvessel density (MVD), but not with TNFα expression. BLCA1 is associated with progression of bladder cancer and paly a role in angiogenesis in bladder cancer.

US$29.90

PMID: 26629142


Other references

Gluzman, 1994: One-dimensional frustrated Heisenberg antiferromagnet of spin 1/2 in a strong magnetic field. Physical Review. B, Condensed Matter 49(17): 11962-11966

Youge, CM., 1973: The nature of reef-building (hermatypic) corals. Bulletin Mar Sci, 231: 1-15

Zhelyazkov, P.; Markova, D., 1993: On the effect of mineral fertilization of seedlings of Pinus sylvestris L. under the conditions of a vegetation experiment with brown mountain forest soil. The edaphic, environmental and biological effects of mineral fertilization of seedlings of Pinus sylvestris L. grown on a brown mountain forest soil comparatively well supplied with nutrients, have been investigated. An estimation was made on the...

Priddy, B.M.; Carmack, S.A.; Thomas, L.C.; Vendruscolo, J.C.M.; Koob, G.F.; Vendruscolo, L.F., 2016: Sex, strain, and estrous cycle influences on alcohol drinking in rats. NlmCategory="UNASSIGNED">Although women appear to be more vulnerable to alcohol-induced pathophysiology than men, the neurobiological basis for sex differences is largely unknown, partially because most studies on alcohol drinking are...

Markina, E.A.; Vodop'ianova, Z.V., 1996: Suppurative pericarditis in patients with terminal kidney failure. Terapevticheskii Arkhiv 68(4): 83-85

Yang, L-lin.; Lv, Z-yue.; Hu, S-min.; He, S-jie.; Li, Z-yu.; Zhang, S-min.; Zheng, H-qin.; Li, M-tao.; Yu, X-bing.; Fung, M-Chiu.; Wu, Z-dao., 2009: Schistosoma japonicum: proteomics analysis of differentially expressed proteins from ultraviolet-attenuated cercariae compared to normal cercariae. Schistosomiasis is considered the most important human helminthiasis in terms of morbidity and mortality. In this study, comparative soluble proteomic analysis of normal cercariae and ultraviolet-irradiated attenuated cercariae (UVAC) from Schisto...

Fallon, N.; Chiu, Y.; Nurmikko, T.; Stancak, A., 2017: Altered theta oscillations in resting EEG of fibromyalgia syndrome patients. Fibromyalgia syndrome (FM) is a chronic pain disorder characterized by widespread pain, sleep disturbance, fatigue and cognitive/affective symptoms. Functional imaging studies have revealed that FM and other chronic pain syndromes can affect resti...

Anonymous, 1980: Research and training for management of arid lands. With special reference to Anglophone Africa and the University of Khartoum. Proceedings of a workshop held at the Institute of Geography, University of Hamburg, Federal Republic of Germany 29 October - 2 November 1979. The objectives of the Workshop were: (1) To review progress on supportive investigations and research projects under the Arid Lands Sub-programme and to advise on further priorities within the sub-programme. (2) To discuss the thematic evolution o...

Levin M.D.; Misharev O.S., 1985: Diagnostic routine for newborns with intestinal obstruction. Pediatriya (Moscow) (9): 24-29

Kats T.S., 1984: Neuroendocrine system in various morphs of megoura viciae homoptera aphididae. Entomological Review (English Translation of Entomologicheskoye Obozreniye) 63(1): 10-19