geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Biocompatibility and safety of PLA and its copolymers


, : Biocompatibility and safety of PLA and its copolymers. Advanced Drug Delivery Reviews 107(): 153-162

NlmCategory="UNASSIGNED">PLA and its copolymers are commonly used for a wide variety of applications. While they are considered to be biocompatible, side effects resulting from their implantation have been reported. The implantation of biomaterials always results in a foreign body reaction. Such a reaction has also been reported following PLA and its copolymers. This article reviews the process of inflammatory reaction that is to be expected following implantation of PLA, and it highlights specific cases in which the inflammatory reaction can result in safety concerns. The authors also review selected cases from different medical fields to demonstrate possible clinical side effects resulting from its use.

US$19.90

PMID: 27058154

DOI: 10.1016/j.addr.2016.03.012


Other references

Martinez Garcia, E.; Vazquez Rojas, J.M.ria; Roca Aleu, J.; Vazquez Rojas, J.L.is, 2004: Device, a probe and a method for introducing and/or collecting fluids in the inside of an animal uterus. The device comprises a tube or catheter 1 that is introduced into the animal's vagina up to the cervix duct 19; a flexible probe 6 constituted of a first flexible tubular body 7, to allow that the probe, after reaching the distal end of the t...

Stryckers, J., 1958: How are weeds injur- ious.. Reviews the various ways in which weeds may be injurious: by depressing yields (the various ways in which competition can occur are outlined), by interfering with harvesting operations, by acting as hosts to pests and diseases, by poisoning live-...

Lemoine, J.M., 1958: Bronchial lesions in tuberculous primary infection. Revista Espanola de Pediatria 14(80): 237-254

Formstecher, P.; Lustenberger, P.; Dautrevaux, M., 1980: Synthesis of steroidal 17 beta-carboxamide derivatives. Several 17 beta-carboxamide derivatives of natural and fluorinated glucocorticoids have been synthesized. The 17 beta-carboxylic derivatives were obtained by periodic acid oxidation of their side chains. They were then activated by N-hydroxybenzot...

Hooper, J.A.; Smith, E.L., 1973: Histone iii part 2 isolation and sequences of chymotryptic peptides from calf thymus histone iii. Journal of Biological Chemistry 248(9): 3255-3260

D.R.ubin M R.; Mulligan C.N.; Gibbs B.F., 1989: Correlation of enhanced surfactin production with decreased isocitrate dehydrogenase activity. The activity of an enzyme in the tricarboxylic acid cycle, isocitrate dehydrogenase EC 1.1.1.42 (ICD), was followed during the production of a biosurfactant, surfactin, by Bacillus subtilis. A mutant suppressed the activity of the enzyme 30 times...

Dote, G.; Letnes, L., 1996: Scholarly journals in agricultural economics libraries/reference rooms: a survey. The study develops a core list of journals for the field of agricultural economics. For this study, the holdings of members of the Agricultural Economics Reference Organization who represent agricultural economics libraries in the USA and Canada w...

Ludwig, G.G., 2002: Hospital diversions affect ambulance productivity. Emergency Medical Services 31(7): 38-40

Isurugi K.; Fukutani K.; Kinoshita K.; Takayasu H.; Wakabayashi K., 1973: Dynamics of serum gonadotropins and responses to synthetic luteinizing hormone releasing hormone in patients with eunuchoidism. Proceedings of Annual Meeting of Japan Endocrinological Society 46: 24

Folk R.M.; Pierre R.L.S., 1972: Interaction of phyto hem agglutinin with mouse lymphoma cells. Federation Proceedings 31(2): 930