+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Chlamydial Antibiotic Resistance and Treatment Failure in Veterinary and Human Medicine

, : Chlamydial Antibiotic Resistance and Treatment Failure in Veterinary and Human Medicine. Current Clinical Microbiology Reports 3(): 10-18

NlmCategory="UNASSIGNED">The Chlamydiaceae are widespread pathogens of both humans and animals. Chlamydia trachomatis infection causes blinding trachoma and reproductive complications in humans. Chlamydia pneumoniae causes human respiratory tract infections and atypical pneumonia. Chlamydia suis infection is associated with conjunctivitis, diarrhea, and failure to gain weight in domestic swine. Chlamydial infections in humans and domesticated animals are generally controlled by antibiotic treatment-particularly macrolides (usually azithromycin) and tetracyclines (tetracycline and doxycycline). Tetracycline-containing feed has also been used to limit infections and promote growth in livestock populations, although its use has decreased because of growing concerns about antimicrobial resistance development. Because Sandoz and Rockey published an elegant review of chlamydial anti-microbial resistance in 2010, we will review the following: (i) antibiotic resistance in C. suis, (ii) recent evidence for acquired resistance in human chlamydial infections, and (iii) recent non-genetic mechanisms of antibiotic resistance that may contribute to treatment failure.


PMID: 27218014

DOI: 10.1007/s40588-016-0028-4

Other references

L.M.r G.N.; Jue T.; Hoffman B.M.; Nagai K., 1984: Proton nmr investigation of the allosteric transition in ligated and unligated carp hemoglobin evidence for structural heterogeneity in the heme pocket. The 1H NMR spectra of carp Hb in the unligated deoxy and ligated met-cyano and met-azido forms were recorded as a function of pH and upon addition of inositol hexaphosphate (IHP). All protein derivatives yield spectra that are consistent with appr...

Cottalorda, J.; Carcassonne, M., 1954: The pre-prostatic venous plexus and the retropubic approach. Lyon Chirurgical 49(4): 467-470

Fuh, C.B.; Wu, M.L., 1999: Impurity analysis of methamidophos with chromatographic methods. An impurity analysis of methamidophos (O,S-dimethyl phosphoramidothioate) which is one of the frequently used pesticides for crop protection was carried out. Four impurity standards by synthesis and purifications to be used for quantitative impuri...

Baier, B.; Zenker, A., 2005: Evaluation procedure using macrozoobenthos in non lotic waters Bewertungsverfahren fuer Makrozoobenthos in stehenden Gewaessern. Limnologie Aktuell, 11: 121-136

Tamas, G.; Ronto, G., 1957: Effect of ultrasonics on cross-striated muscles. Kiserletes Orvostudomany 9(5-6): 595-600

Reglodi, D.; Lubics, A.; Tamas, A.; Szalontay, L.; Lengvari, I., 2003: Effects of PACAP treatment in a rat model of Parkinsons disease. Regulatory Peptides 115(1): 54, 15 August

Karatygin, I.V., 2006: Fungi as components of ecosystems of the past. Recent progress in the palacomycological studies is presented in the review. The span of geologic time from the Devonian upwards is examined from many sources of information in relation to major taxonomic and trophic groups of fungi. Special atten...

Li, Y.; Liu, Z.; Liu, B.; Zhao, T.; Chong, W.; Wang, Y.; Alam, H.B., 2014: Citrullinated histone H3: a novel target for the treatment of sepsis. We have recently demonstrated that in a rodent model of lipopolysaccharide (LPS)-induced shock, an increase in circulating citrullinated histone H3 (Cit H3) is associated with lethality of sepsis, and treatment with suberoylanilide hydroxamic acid...

Furlini, G.; Re, M.C.; Vignoli, M.; Ramazzotti, E.; Monari, P.; L.P.aca, M., 1995: The lack of susceptibility to HIV-1 infection in human hematopoietic progenitor TF-1 cell line correlates with the absence of LFA-1 (CD11a) surface adhesion molecule. Although substantially unsusceptible to HIV-1 infection, human hematopoietic progenitors (CD34+ cells) express significant amounts of gp120-binding CD4 molecules. As some experimental evidence suggests the need for one or more putative cellular ac...

Possinger, K.; Wilmanns, W., 1993: Palliative therapeutic control of tumor progression in patients with metastatic breast cancer. Der Internist 34(4): 340-350