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Comparing Type 2 Diabetes, Prediabetes, and Their Associated Risk Factors in Asian Indians in India and in the U.S.: The CARRS and MASALA Studies

, : Comparing Type 2 Diabetes, Prediabetes, and Their Associated Risk Factors in Asian Indians in India and in the U.S.: The CARRS and MASALA Studies. Diabetes Care 38(7): 1312-1318

To assess the prevalence of diabetes and prediabetes and the associated risk factors in two Asian Indian populations living in different environments. We performed cross-sectional analyses, using representative samples of 2,305 Asian Indians aged 40-84 years living in Chennai, India, from the Centre for cArdiometabolic Risk Reduction in South-Asia study (CARRS) (2010-2011), and 757 Asian Indians aged 40-84 years living in the greater San Francisco and Chicago areas from the U.S. Mediators of Atherosclerosis in South Asians Living in America (MASALA) study (2010-2013). Diabetes was defined as self-reported use of glucose-lowering medication, fasting glucose ≥126 mg/dL, or 2-h glucose ≥200 mg/dL. Prediabetes was defined as fasting glucose 100-125 mg/dL and/or 2-h glucose 140-199 mg/dL. Age-adjusted diabetes prevalence was higher in India (38% [95% CI 36-40]) than in the U.S. (24% [95% CI 21-27]). Age-adjusted prediabetes prevalence was lower in India (24% [95% CI 22-26]) than in the U.S. (33% [95% CI 30-36]). After adjustment for age, sex, waist circumference, and systolic blood pressure, living in the U.S. was associated with an increased odds for prediabetes (odds ratio 1.2 [95% CI 0.9-1.5]) and a decreased odds for diabetes (odds ratio 0.5 [95% CI 0.4-0.6]). These findings indicate possible changes in the relationship between migration and diabetes risk and highlight the growing burden of disease in urban India. Additionally, these results call for longitudinal studies to better identify the gene-environment-lifestyle exposures that underlie the elevated risk for type 2 diabetes development in Asian Indians.


PMID: 25877810

DOI: 10.2337/dc15-0032

Other references

E.A.abi E.H.ssane; Diez Jose Bienvenido; Broutin Jean; Essamoud Rachid, 2006: First palynological characterization of the Middle Triassic; implications for the first Tethysian rifting phase in Morocco. The Middle Anisian has been palynologically characterized for the first time, at the whole Moroccan scale, in the High Atlas of Marrakech. The stratigraphic, tectonic and paleogeographic implications of this discovery are analysed.

Dice, L.R., 1918: Notes on the nesting of the Redpoll (Acanths linaria linaria). Condor Hollywood, 20 129-131

Depuydt, S.; Rodriguez-Villalon, A.; Santuari, L.; Wyser-Rmili, Céline.; Ragni, L.; Hardtke, C.S., 2013: Suppression of Arabidopsis protophloem differentiation and root meristem growth by CLE45 requires the receptor-like kinase BAM3. Peptide signaling presumably occupies a central role in plant development, yet only few concrete examples of receptor-ligand pairs that act in the context of specific differentiation processes have been described. Here we report that second-site n...

Marlow, H.W., 1950: Pituitary-comb relationship. Saline extracts of frozen chick pituitaries injd. into capons gave significant increases in growth in both length and height of their combs. Saline extracts of fresh bovine pituitaries, in very large doses, had no effect on comb growth. Purified A...

Khoroshkov V.S.; Belyaikin E.V.; Breev V.M.; Kostyuchenko V.I.; Lisovets S.P.; Lomanov M.F.; Pokhvata V.P.; Shimchuk G.G., 1987: Special topographic and dosimetric features of different proton irradiation techniques. Meditsinskaya Radiologiya 32(8): 70-76

Kugathasan, S.; Judd, R.H.; Hoffmann, R.G.; Heikenen, J.; Telega, G.; Khan, F.; Weisdorf-Schindele, S.; San Pablo, W.; Perrault, J.; Park, R.; Yaffe, M.; Brown, C.; Rivera-Bennett, M.T.; Halabi, I.; Martinez, A.; Blank, E.; Werlin, S.L.; Rudolph, C.D.; Binion, D.G., 2003: Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: a statewide population-based study. Objective: To define epidemiologic and clinical characteristics of newly diagnosed pediatric inflammatory bowel disease (IBD) in a large population-based model. Study design: All pediatric gastroenterologists providing care for Wisconsin children...

Mesquita J.F., 1968: The ultrastructural modifications produced by phenyl urethane in the merismatic cells of the roots of allium cepa m. Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences Serie D Sciences Naturelles 267(3): 303-305

Reuter, A., 1954: Cervical intervertebral disk displacement. Zeitschrift für die Gesamte Innere Medizin und Ihre Grenzgebiete 9(19-20): 1011-1016

Orley, L., 1884: Die Kiemen der Serpulaceeu und ihre morphologische Bedeutung. The investigations of Orley (58) into the minute structure of the gills of Serpulids point to the opercular plate, which is a modification of some of the gill-threads, having a respiratory function ; it is richly supplied with capillaries. There i...

Weitzman, L.N.; Kalyuzhnov, V.T.; Voroshilova, N., 1970: Siberian white guinea-fowl for broiler production. In 1963, 2 white males and 1 white female appeared among the progeny of grey guinea-fowl. By the end of 1969 the new breed, named Siberian, numbered approx. 3000. Siberians are similar grey guinea-fowl in adult body weight, and are superior in egg...