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Comparison of the chemical profiles of fresh-raw and dry-processed Juglans mandshurica

, : Comparison of the chemical profiles of fresh-raw and dry-processed Juglans mandshurica. Journal of Separation Science (): -

NlmCategory="UNASSIGNED">The processing of Juglans mandshurica maxim. is important to reduce its toxicity and enhance its efficacy. Simple, efficient, and sensitive ultra high performance liquid chromatography coupled with a time-of-flight mass spectrometry-based chemical profiling approach was proposed to rapidly evaluate the chemical difference between fresh and dry samples. Under the optimised ultra high performance liquid chromatography and quadrupole time-of-flight tandem mass spectrometry conditions, 81 significantly different compounds were rapidly discovered using principal component analysis, and then tentatively identified by comparison with reference substances or inferred through mass spectral fragment ion analysis and literature data. These compounds included 35 naphthoquinones, 11 diarylheptanoids, 9 flavonoids, 8 triterpenes, 12 phenolic acids, and 6 aliphatics. The results demonstrated that chemical reactions occurring during processing could be used to elucidate the processing mechanism of Juglans mandshurica Maxim. This study provides a novel approach to identifying complicated components of various complex mixtures in fresh-raw and dry-processed traditional Chinese medicines, which could be used as a valid analytical method to further understand the processing mechanisms of these medicines, as well as providing intrinsic quality control of the medicines and their processed products. This article is protected by copyright. All rights reserved.


PMID: 27878950

DOI: 10.1002/jssc.201600877

Other references

Wanke H., 1965: The solar wind as the source of the primordial rare gases in stone meteorites. Zeitschrift fuer Naturforschung Teil A: Astrophysik, Physik und Physikalische Chemie

Peress N.S.; Gruenewald R.; Carioto L.A., 1985: Intra ocular and central nervous system listeriosis following systemic infection in wistar rats with chronic serum sickness. The relationship of immune complex deposits and cell-mediated immunity to the occurrence of ocular and brain listeriosis following a low (0.007-0.03 LD50) intraperitoneal challenge was investigated in 68 Wistar rats with chronic experimental serum...

Bruce, L.L.; Stein, B.E., 1988: Transient projections from the lateral geniculate to the posteromedial lateral suprasylvian visual cortex in kittens. The postnatal maturation of the projection from the lateral geniculate nucleus to the posteromedial lateral suprasylvian visual cortex (PMLS) was studied with injections of fluorescent dyes into the PMLS at various postnatal ages. Labeled neurons...

Junqueira, O.M.; Fonseca, L.E.C.; Araujo, L.F.; Sakomura, N.K.; Faria, D.E., 1999: Performance and haematological parameters of broilers under feed restriction and receiving hydroelectrolytic solutions. The effect of sodium bicarbonate and its addition to ammonium chloride via drinking water and of feed restriction on performance and haematological parameters of broilers from 22 to 42 days of age was studied. The study comprised a completely rand...

Huerre, M.R.; Piens, M.A., 1996: Histopathology of protozoa. Protozoa are single-celled animals hosted by animals and humans. Numerous parasites can be considered to be non-pathogenic for humans but, in tropical countries, pathology caused by protozoa is a major public health problem. The study of parasitic...

Daniels, J.L.; Longnecker, M.P.; Rowland, A.S.; Golding, J., 2004: Fish intake during pregnancy and early cognitive development of offspring. Fish is a source of many nutrients that can be beneficial during pregnancy, as well as a source of neurotoxicant contaminants such as methylmercury. Previous investigations of fish intake in relation to neurodevelopment have focused on possible da...

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Hatanaka, S.I., 1959: Oligosaccharides in the seeds of Sesamum indicum L. The defatted seeds of Sesamum proved to contain glucose (a trace), sucrose (1%), a trisaccharide (0.5%), a tetrasaccharide (0.1%) and higher oligosaccharides (a trace). Among them tri and tetrasaccharides were isolated with the use of carbon-Celit...

Grimaldi, A., 1946: Researches on weeds in Umbria. Damage caused by some weeds to wheat cultivation. Avena fatua (wild oats) and Vicia sativa (vetch) are predominant on other wheat weeds in Umbria. In 5-years' trials, the nature and amount of damage caused by these 2 weeds to wheat cultivation have been investigated.

Manoogian, S.J.; McNally, C.; Stitzel, J.D.; Duma, S.M., 2009: Dynamic biaxial tissue properties of pregnant porcine uterine tissue. Automobile crashes are the largest single cause of death for pregnant females and the leading cause of traumatic fetal injury mortality in the United States. Current research for pregnant occupant safety utilizing computational models is limited b...