+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Compensatory recombination phenomena of neurological functions in central dysphagia patients

, : Compensatory recombination phenomena of neurological functions in central dysphagia patients. Neural Regeneration Research 10(3): 490-497

We speculate that cortical reactions evoked by swallowing activity may be abnormal in patients with central infarction with dysphagia. The present study aimed to detect functional imaging features of cerebral cortex in central dysphagia patients by using blood oxygen level-dependent functional magnetic resonance imaging techniques. The results showed that when normal controls swallowed, primary motor cortex (BA4), insula (BA13), premotor cortex (BA6/8), supramarginal gyrus (BA40), and anterior cingulate cortex (BA24/32) were activated, and that the size of the activated areas were larger in the left hemisphere compared with the right. In recurrent cerebral infarction patients with central dysphagia, BA4, BA13, BA40 and BA6/8 areas were activated, while the degree of activation in BA24/32 was decreased. Additionally, more areas were activated, including posterior cingulate cortex (BA23/31), visual association cortex (BA18/19), primary auditory cortex (BA41) and parahippocampal cortex (BA36). Somatosensory association cortex (BA7) and left cerebellum in patients with recurrent cerebral infarction with central dysphagia were also activated. Experimental findings suggest that the cerebral cortex has obvious hemisphere lateralization in response to swallowing, and patients with recurrent cerebral infarction with central dysphagia show compensatory recombination phenomena of neurological functions. In rehabilitative treatment, using the favorite food of patients can stimulate swallowing through visual, auditory, and other nerve conduction pathways, thus promoting compensatory recombination of the central cortex functions.


PMID: 25878601

DOI: 10.4103/1673-5374.153701

Other references

Ishikado, A.; Imanaka, H.; Kotani, M.; Fujita, A.; Mitsuishi, Y.; Kanemitsu, T.; Tamura, Y.; Makino, T., 2005: Liposomal lactoferrin induced significant increase of the interferon-alpha (IFN-alpha) producibility in healthy volunteers. Interferon-alpha (IFN-alpha) producibility has been widely accepted as one of the important markers to evaluate the immune status. In this study, preliminary clinical tests were carried out to confirm the immunomodulatory activity of liposomal lac...

Sasaki M.; Yamada F.; Kobayashi S., 1990: A sensitive enzyme immunoassay for semi alkaline proteinase from aspergillus melleus. A sensitive enzyme immunoassay for semi-alkaline proteinase (SAP) was developed, based on the sandwiching of an antigen between anti-SAP IgG-coated polystyrene beads and anti-SAP Fab'-linked peroxidase conjugate. A calibration curve for the s...

Smith, C.A.; Joss, J.M., 1994: Steroidogenic enzyme activity and ovarian differentiation in the saltwater crocodile, Crocodylus porosus. It has been hypothesized that steroid hormone production is involved in sexual differentiation of the gonads in reptiles with temperature-dependent sex determination. We have therefore examined steroidogenic enzymes and ovarian differentiation in...

Khan, I.A.; Ely, K.H.; Kasper, L.H., 1994: Antigen-specific CD8+ T cell clone protects against acute Toxoplasma gondii infection in mice. Encephalitis caused by the obligate intracellular protozoan, Toxoplasma gondii, is a major cause of morbidity and mortality in those afflicted with AIDS. The cell-mediated response is critical for host immunity against this parasite. A panel of T...

Faure F.; Jitsukawa S.; Meuer S.; Bohuon C.; Triebel F.; Hercend T., 1988: Identification of a cd2 negative cd3 positive t cell receptor gamma positive peripheral blood lymphocyte subpopulation. We have identified, in a healthy individual, a subpopulation of human peripheral lymphocytes which surface express a CD3-TCR-.gamma. complex recognized by anti-Ti.gamma.A mAb, while being unreactive with a phycoerythrin-conjugated anti-CD2 antibod...

Astapov A.A.; Amvrosiev Y.A.; Tsynkalovskii I.B., 1974: The intensity of selection of drug resistant forms of escherichia depending on the drugs used to treat patients with acute dysentery. Antibiotiki (Moscow) 19(3): 279

Sullivan M.J.; Harvey R.A.; Shimamura T., 1977: Experimental pyelo nephritis the role of polymorphonuclear leukocytes and complement system in structural damage to the rat kidney. Federation Proceedings 36(3): 1070

Both-de Vries, A.C.; Bus, A.G., 2010: The proper name as starting point for basic reading skills. Does alphabetic-phonetic writing start with the proper name and how does the name affect reading and writing skills? Sixty 4- to 5(1/2)-year-old children from middle SES families with Dutch as their first language wrote their proper name and named...

Tanaka, T.; Akazawa, N.; Ozaki, Y.; Matsumura, Y.; Ohmori, H., 1984: Malignant fibrous histiocytoma originating in the left spermatic cord with a review of 14 cases in the literature. An 84-yr-old man developed a small-finger-tip sized tumor in the left inguinal area about five to six years prior to consultation with the Urology Department. Later, the tumor extended to the scrotum and the suprapubic area. Histological examinati...

Epstein, S.E., 2002: The multiple mechanisms by which infection may contribute to atherosclerosis development and course. Circulation Research 90(1): 2-4