+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Complication timing impacts 30-d mortality after hepatectomy

, : Complication timing impacts 30-d mortality after hepatectomy. Journal of Surgical Research 203(2): 495-506

To date, no study has specifically focused on the timing of complications after hepatectomy relative to patient outcomes. We sought to investigate the effect of complication timing on 30-d mortality. A total of 3064 patients who underwent hepatic resection in 2014 were identified from American College of Surgeons National Surgical Quality Improvement Program database. Cox regression analysis was performed to determine the association of complication timing with 30-d mortality. Median patient age was 60 y (interquartile range, 50-68). Among all patients who experienced a complication, 16.6% had only a postdischarge complication. Wound disruption (64%) and surgical site infection (58.1%) occurred frequently after discharge. Organ space surgical site infection occurred at a later time after surgery among patients who underwent minimally invasive surgery (minimally invasive surgery, 16 d versus open 10 d; P = 0.008). Among 47 (1.5%) patients who died within 30 d from surgery, 21.3% of deaths occurred postdischarge. After adjusting for competing risk factors, patients who had experienced a postdischarge complication demonstrated an increased risk of 30-d mortality (referent, predischarge, hazard ratio 2.96, 95% confidence intervals 1.07-8.17; P = 0.04). Postdischarge complications occurred less frequently after hepatectomy than predischarge complications; however, late complications were associated with a three-fold increased risk of mortality.


PMID: 27363661

DOI: 10.1016/j.jss.2016.04.047

Other references

Herold, H.J.; Bockmühl, F., 1966: On the incidence, sex and age distribution of laryngeal carcinomas. Zeitschrift für Laryngologie, Rhinologie, Otologie und Ihre Grenzgebiete 45(12): 785-789

Anonymous, 1983: Hewlett packard. Analytical Chemistry 55(2): 209a-209a

Xu, C.; Zou, M.; Liu, Y.; Ren, J.; Tian, Y.; Yan, J.; Wang, Y.; Cheng, G., 2012: Pharmacokinetics of carbamazepine polymorphs and dihydrate in rats, related to dogs and humans. Species differences in the oral pharmacokinetics and absolute bioavailability (F ( abs )) of carbamazepine polymorphs (form I and form III) and dihydrate were studied. The pharmacokinetics of each form was investigated in rats following a single o...

Kulevanova, S.; Panovska, T.K.difkova, 2002: Inhibition of thermal autooxidation of lard by antioxidative action of Thymus extracts. Antioxidant activity of five Thymus L. (Lamiaceae) species from Macedonian flora was investigated. Ether and ethyl acetate extracts from overgrown herbal parts were prepared and added to the antioxidant and peroxide-free lard. The Wheeler method w...

Marrou J.; Molot P.; Navatel J.; Fournier B., 1972: Sanitary selection of strawberry plants in france. Actas do Congresso da Uniao Fitopatologica Mediterranea : 413-414,

Katsiki, N.; Mikhailidis, D.P.; Nair, D.R., 2015: The effects of antiepileptic drugs on vascular risk factors: a narrative review. Epilepsy is associated with increased cardiovascular disease (CVD) morbidity and mortality. The exact causes of this link are not clearly defined. The role of antiepileptic drugs (AEDs) in influencing CVD risk in patients with epilepsy remains con...

Meira, A.R., 1988: Artificial fertility: a new ethical approach in Brazil. Fertility and Sterility 50(3): 535-536

Yuan DiShun, 1994: The mechanism of evolution of pesticide resistance in tea pests. The mechanisms of insecticide resistance and factors influencing it are discussed for tea pests with particular reference to genetic, biological and external aspects. Measures for overcoming or postponing the development of resistance are recommen...

Fresco, D., M.; Williams, N., L.; Nugent, N., R., 2006: Flexibility and negative affect: Examining the associations of explanatory flexibility and coping flexibility to each other and to depression and anxiety. Recent research on vulnerabilities to depression and anxiety has begun to de-emphasize cognitive content in favor of the responsiveness of the individual to variations in situational context in arriving at explanations of events (explanatory flex...

Pereverzev, Y.V.; Prezhdo, O.V., 2006: Force-induced deformations and stability of biological bonds. A deformation model of the forced-induced dissociation of biological bonds is developed. A simple illustration shows that protein deformations can change the receptor-ligand interaction linearly with applied force at small forces, either increasin...