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Cost-utility of collaborative care for major depressive disorder in primary care in the Netherlands

, : Cost-utility of collaborative care for major depressive disorder in primary care in the Netherlands. Journal of Psychosomatic Research 79(4): 316-323

Major depression is a great burden on society, as it is associated with high disability/costs. The aim of this study was to evaluate the cost-utility of Collaborative Care (CC) for major depressive disorder compared to Care As Usual (CAU) in a primary health care setting from a societal perspective. A cluster randomized controlled trial was conducted, including 93 patients that were identified by screening (45-CC, 48-CAU). Another 57 patients were identified by the GP (56-CC, 1-CAU). The outcome measures were TiC-P, SF-HQL and EQ-5D, respectively measuring health care utilization, production losses and general health related quality of life at baseline three, six, nine and twelve months. A cost-utility analysis was performed for patients included by screening and a sensitivity analysis was done by also including patients identified by the GP. The average annual total costs was €1131 (95% C.I., €-3158 to €750) lower for CC compared to CAU. The average quality of life years (QALYs) gained was 0.02 (95% C.I., -0.004 to 0.04) higher for CC, so CC was dominant from a societal perspective. Taking a health care perspective, CC was less cost-effective due to higher costs, €1173 (95% C.I., €-216 to €2726), of CC compared to CAU which led to an ICER of 53,717 Euro/QALY. The sensitivity analysis showed dominance of CC. The cost-utility analysis from a societal perspective showed that CC was dominant to CAU. CC may be a promising treatment for depression in the primary care setting. Further research should explore the cost-effectiveness of long-term CC. Netherlands Trial Register ISRCTN15266438.


PMID: 26255095

DOI: 10.1016/j.jpsychores.2015.06.006

Other references

Pecher, R., 1992: Stormwater treatment in combined sewer systems in Germany. Water Science & Technology 26(1-11): 1841-1849

Giles, G.M., 1883: On the Pathogenesis of Pneumonia. British Medical Journal 2(1175): 10-11

Stoop, J.M.H.; Pharr, D.M., 1993: Mannitol 1-oxidoreductase activity, relative growth rate and carbon use of celery suspension cultures grown on different carbon sources. Plant Physiology (Rockville) 102(1 SUPPL ): 58

Parker, Raymond C., 1927: The effect of selection in pedigree lines of Infusoria. In Paramecium aurelia it is possible to establish among the descendants of 1 animal, reproducing vegetatively, 2 diverse sets which differ in division rate. Control lines (non-selected), derived from the same animal in the beginning, followed a co...

Plascencia, A.; Arellano, G.E.; Calderon, J.F.; Lopez Soto, M.A.; Zinn, R.A., 1998: Influence of cracked, gross grind or finely grind of corn on digestion and rumen function in steers fed a corn-based finishing diet. Journal of Dairy Science 81(SUPPL 1): 337

Simonds, J., 1977: The role of the landscape architect in botanical garden development. Arboretum and botanical garden bulletin: 11 (2) 37-42

Tin, S.Sai.; Wiwanitkit, V., 2014: Only fixation for lumbar canal stenosis. Journal of Craniovertebral Junction & Spine 5(2): 106-106

Sitton, O.; Foutch, G.; Book, N.; Gaddy, J., 1979: Ethanol from agricultural residues. Process biochemistry 14(9): 7-10

Melander, B.; Rasmussen, K., 2000: Reducing intrarow weed numbers in row crops by means of a biennial cultivation system. Intrarow weed emergence in row crops can be reduced by means of a biennial cultivation system that is based on an exhaustion of the weed seed bank in the upper soil layer of crop-free bands established in a preceding cereal crop, year I, before th...

Terui, M.; Kagawa, H., 1957: The influence of trichomycin on the germination of the apple blossom-blight fungus and the apple pollen. The effect of trichomycin, isolated from Streptomyces hachijoensis, as a spray fungicide to control apple blossom-blight (Sclerotinia mali) was studied. A concentration of 50 g/cc trichomycin was found to be ideal as it did not retard the germinat...