+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Cytotoxicity of glass ionomer cements containing silver nanoparticles

, : Cytotoxicity of glass ionomer cements containing silver nanoparticles. Journal of Clinical and Experimental Dentistry 7(5): E622-E627

Some studies have investigated the possibility of incorporating silver nanoparticles (NAg) into dental materials to improve their antibacterial properties. However, the potential toxic effect of this material on pulp cells should be investigated in order to avoid additional damage to the pulp tissue. This study evaluated the cytotoxicity of conventional and resin-modified glass ionomer cements (GIC) with and without addition of NAg. NAg were added to the materials at two different concentrations by weight: 0.1% and 0.2%. Specimens with standardized dimensions were prepared, immersed in 400 µL of culture medium and incubated at 37°C and 5% CO2 for 48 h to prepare GIC liquid extracts, which were then incubated in contact with cells for 48 h. Culture medium and 0.78% NAg solution were used as negative and positive controls, respectively. Cell viability was determined by MTT and Trypan Blue assays. ANOVA and the Tukey test (α=0.05) were used for statistical analyses. Both tests revealed a significant decrease in cell viability in all groups of resin modified cements (p<0.001). There were no statistically significant differences between groups with and without NAg (p>0.05). The differences in cell viability between any group of conventional GIC and the negative control were not statistically significant (p>0.05). NAg did not affect the cytotoxicity of the GIC under evaluation. Glass ionomer cements, totoxicity, cell culture techniques, nanotechnology, metal nanoparticles.


PMID: 26644839

DOI: 10.4317/jced.52566

Other references

Irwin, Will, 1873, 1988: Good employees are made, not born. American Nurseryman 167: 5

Yamanishi, O.K.yoshi; Nakajima, Y.; Hasegawa, K., 1993: Influence of trunk strangulation on growth and water absorption by young pummelo trees exposed to high temperature. Young 'Tosa Buntan' pummelo (Citrus grandis (L.) Osbeck) trees on trifoliate orange (Poncirus trifoliata Raf.) rootstock were sand-cultured in the pots and transferred to a growth chamber kept at 30 degree /25 degree C (day/night) from e...

Manickavasagam, J.; Majumdar, S.; Bhattacharyya, A.K., 2008: Focal inflammatory myositis of the paraspinal neck muscles. Ear, Nose, & Throat Journal 87(8): 430-432

Yoshioka, T.; Kojima, I.; Isshiki, K.; Watanabe, A.; Shimauchi, Y.; Okabe, M.; Fukagawa, Y.; Ishikura, T., 1983: Structures of OA-6129A, B1, B2 and C, new carbapenem antibiotics produced by Streptomyces sp. OA-6129. The chemical structures of OA-6129A, B1, B2 and C, new carbapenem antibiotics having a pantetheinyl group at C-3 were elucidated by spectroscopic analysis and chemical transformation as presented in Fig. 1.

Melisa Blackhall; Estela Raffaele; Thomas T.V.blen, 2012: Is foliar flammability of woody species related to time since fire and herbivory in northwest Patagonia, Argentina?. In northwest Patagonia burning of fire-resistant forests creates a community-level positive feedback towards increased fire occurrence because of successional replacement by fire-prone shrublands. We hypothesize that variability in plant traits re...

Gupta, M.P.; Chandra, J.P., 1979: Vegetative propagation of coniferous forest tree species from branch cuttings with the help of mist chamber. A brief description, with diagrams, is given of a mist chamber constructed at Simla. Softwood cuttings of Pinus roxburghii and semi-hardwood cuttings of P. wallichiana, P. gerardiana, Picea smithiana, Abies pindrow and Cedrus deodara were set in s...

Graves, Gary R., 1993: A new hybrid manakin from the Andean foothills of eastern Ecuador. A new intergeneric hybrid manakin (Dixiphia pipra times pipra filicauda) is described from the Andean foothills of eastern Ecuador. The adult male specimen represents the first record of hybridization among species belonging to different clades of...

Kawecki, D.; Szczurek-Katański, K.; Jacheć, W.; Szyguła, J.; Walichiewicz, P.; Tomasik, A.; Wilczewski, Pław.; Fudal, M.; Rybczyk, R.; Glanowska, G.; Wodniecki, J., 2003: Interventional treatment of myocardial infarction. Own experience. The aim of the study is the analysis of own results of myocardial infarction treatment using percutaneous coronary intervention (PCI) in the setting of twenty-four hour long hemodynamic service. Between 01.12.1998 and 31.12.2001 249 patients with...

Rizwani, W.; Alexandrow, M.; Chellappan, S., 2009: Prohibitin physically interacts with MCM proteins and inhibits mammalian DNA replication. Prohibitin, a tumor suppressor protein, has been shown to repress E2F-mediated transcription and arrest cell cycle progression. while prohibitin has been proposed to regulate cell cycle progression by repressing transcriptional targets of E2F1, it...

Calero R.; Martinez F.; Hernandez S.; Acosta I., 1978: Parasitism of buteo buteo aves accipitridae by trichinella sp in the zoo of jerez de la frontera spain. Revista Iberica de Parasitologia 38(1-2): 135-138