geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Dosimetric comparison of moderate deep inspiration breath-hold and free-breathing intensity-modulated radiotherapy for left-sided breast cancer


, : Dosimetric comparison of moderate deep inspiration breath-hold and free-breathing intensity-modulated radiotherapy for left-sided breast cancer. Cancer Radiotherapie 19(3): 180-186

This study determined the dosimetric comparison of moderate deep inspiration breath-hold using active breathing control and free-breathing intensity-modulated radiotherapy (IMRT) after breast-conserving surgery for left-sided breast cancer. Thirty-one patients were enrolled. One free breathe and two moderate deep inspiration breath-hold images were obtained. A field-in-field-IMRT free-breathing plan and two field-in-field-IMRT moderate deep inspiration breath-holding plans were compared in the dosimetry to target volume coverage of the glandular breast tissue and organs at risks for each patient. The breath-holding time under moderate deep inspiration extended significantly after breathing training (P<0.05). There was no significant difference between the free-breathing and moderate deep inspiration breath-holding in the target volume coverage. The volume of the ipsilateral lung in the free-breathing technique were significantly smaller than the moderate deep inspiration breath-holding techniques (P<0.05); however, there was no significant difference between the two moderate deep inspiration breath-holding plans. There were no significant differences in target volume coverage between the three plans for the field-in-field-IMRT (all P>0.05). The dose to ipsilateral lung, coronary artery and heart in the field-in-field-IMRT were significantly lower for the free-breathing plan than for the two moderate deep inspiration breath-holding plans (all P<0.05); however, there was no significant difference between the two moderate deep inspiration breath-holding plans. The whole-breast field-in-field-IMRT under moderate deep inspiration breath-hold with active breathing control after breast-conserving surgery in left-sided breast cancer can reduce the irradiation volume and dose to organs at risks. There are no significant differences between various moderate deep inspiration breath-holding states in the dosimetry of irradiation to the field-in-field-IMRT target volume coverage and organs at risks.

US$19.90

PMID: 25921618

DOI: 10.1016/j.canrad.2015.01.003


Other references

Frassica, F.J.; Inoue, N.; Virolainen, P.; Chao, E.Y., 1997: Skeletal system: biomechanical concepts and relationships to normal and abnormal conditions. The human skeleton is a remarkable organ that is uniquely designed to provide structural support and to house the body's hematopoietic system and mineral reservoirs. Seven concepts that will assist the clinician in understanding skeletal func...

Percy, R.G.; Mayo, O.L.; Ulloa, M.; Cantrell, R.G., 2006: Registration of AGC85, AGC208, and AGC375 upland cotton germplasm lines. The cotton (Gossypium hirsutum) germplasm lines AGC85, AGC208 and AGC375 were developed by the USDA-ARS and Cotton Incorporated and released in 2005. The lines possess superior fibre length and strength characteristics and improved yield performan...

Collart, A., 1946: A propos dailes. Bull Soc Nat Belges Bruxelles, 27: 32-35

de Figueiredo, L.Francisco.Poli., 2002: Airway obstruction after central venous catheterization. Revista Da Associacao Medica Brasileira 48(1): 24-25

Flood, C.M., 1953: Antepartum femoral thrombosis. Journal of Obstetrics and Gynaecology of the British Empire 60(5): 706-709

Handel, J., 1993: Relaxation techniques for insects. Techniques for relaxing dried specimens of insects so that their anatomy and taxonomy can be studied are reviewed.

Anonymous, 2004: A disabling injury or long-term illness. Journal of the American Veterinary Medical Association 225(6): 826-827

Butucea, L.V.; Mugescu, O.; Matei, C.; Manolescu, L.C.; Badescu, M.; Balan, C.; Palicari, G., 1977: Concentration of ions in deficiency rickets. Plasma and urine from 76 infants 3 to 18 months old with deficiency rickets and from 30 healthy infants were studied. Those with florid hypocalcaemic types of rickets had increased Na in urine, 167 mEq/litre. Plasma K was increased, 5.4 to 5.6 mEq...

Wang, J.B.; Patterson, R.E.; Ang, A.; Emond, J.A.; Shetty, N.; Arab, L., 2014: Timing of energy intake during the day is associated with the risk of obesity in adults. The timing of energy intake is a modifiable behaviour that may influence energy regulation and the risk of obesity. We examined the associations of energy intake in the morning, midday and evening with body mass index (BMI) (n = 239). Cross-sectio...

Papini, S.; Ruglass, L.M.; Lopez-Castro, T.; Powers, M.B.; Smits, J.A.J.; Hien, D.A., 2016: Chronic Cannabis Use Is Associated With Impaired Fear Extinction in Humans. NlmCategory="UNASSIGNED">The use of fear conditioning and extinction paradigms to examine intermediate phenotypes of anxiety and stress-related disorders has facilitated the identification of neurobiological mechanisms that underlie s...