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Effects of high progesterone on outcomes of in vitro fertilization-embryo transfer in patients with different ovarian responses


, : Effects of high progesterone on outcomes of in vitro fertilization-embryo transfer in patients with different ovarian responses. Systems Biology in Reproductive Medicine 61(3): 161-167

The data of 3,841 cycles undergoing in vitro fertilization-embryo transfer (IVF-ET) in our reproductive Center between January 2003 and December 2013 were retrospectively analyzed. According to the number of oocytes retrieved, this study was divided into the high ovarian response group (oocyte retrieval≥20, 842 cycles), the moderate ovarian response group (5<oocyte retrieval<20, 2008 cycles), and the low ovarian response group (oocyte retrieval≤5, 991 cycles). The treatment outcomes were compared between the patients with an increased progesterone (P) level and the patients where the P level did not increase. With increase in ovarian response, the cut-off values of serum P on the day of human chorionic gonadotrophin (hCG) rose, and respectively were 2.5 ng/ml in the high ovarian response group, 2.25 ng/ml in the moderate ovarian response group, and 1.5 ng/ml in the low ovarian response group. In each group, the clinical pregnancy rate and embryo implantation rate were lower in the patients with an increased P level compared to those where the P level did not increase (all p<0.05). However, there were no significant difference in the fertilization rate, cleavage rate, and high-quality embryo rate (all p>0.05). The increased level of P on the day of hCG may affect the treatment outcomes of IVF-ET. The cut-off values of serum P seem to be associated with ovarian response. Increased ovarian response causes the cut-off values of serum P to rise.

US$19.90

PMID: 25915151

DOI: 10.3109/19396368.2015.1033779


Other references

Manzoni, G., 1983: Echos du Dauphine (2e note) (Lep. Papilionidae, Hesperiidae, Nymphalidae, Arctiidae et Zygaenidae). Alexanor. 1982 ; 128: 381-383

Fauconier, I.N.; Jarow, J.P., 1993: Transrectal ultrasound findings in infertile men. Journal of Urology 149(4 SUPPL ): 436A

Anand, S.C.; Brar, G.S., 1981: New races of cyst nematodes. Two new races of Heterodera glycines have been isolated: TN-79 (from an infested field in Tennessee, USA), similar to an isolate reported from Japan and classified as race 5, and P4 (developed by repeated reproduction and selection of nematodes on...

Elmi, M.; Hussein, H.; Nofech-Mozes, S.; Curpen, B.; Leahey, A.; Look Hong, N., 2017: Budget impact analysis of a breast rapid diagnostic unit. The Odette Cancer Centre's recent implementation of a rapid diagnostic unit (rdu) for breast lesions has significantly decreased wait times to diagnosis. However, the economic impact of the unit remains unknown. This project defined the devel...

Reissig, W.H.; Wilde, G.E., 1971: Feeding responses of western corn rootworm on silks of fifteen genetic sources of corn. Water extracts and whole silks of 15 genetic sources of maize were exposed to feeding by adults of Diabrotica virgifera Lec. in the laboratory in Kansas. Significant differences in beetle preference were found in two-choice feeding tests.

Anonymous, 2013: Range extension of the critically endambersngered true poison-dart frog, Phyllobates terribilis Anura Dendrobatidae, in western Colombia. The poison-dart frog Phyllobates terribilis is currently classified as endangered or critically endangered due to its extremely restricted geographic distribution and intensive smuggling by pet traffickers. Based on molecular data, we here report...

Macaire J.J., 1983: Evolution of the hydrographic network in southwestern Paris Basin during the Pliocene and Quaternary. Bulletin de l'Association Francaise pour l'Etude du Quaternaire: 6, Pages 183-195. 1983.

Voigt Thomas; von Eynatten Hilmar; Franzke Hans Joachim, 2004: Late Cretaceous unconformities in the Subhercynian Cretaceous Basin (Germany). Acta Geologica Polonica 54(4): 673-694

Leferink, T.R.efhuis, H., 1973: Six-year nitrogen trial at Groot Avink in eastern Gelderland. Stikstof 'S Grav: 73, 74 (7)

Angle C.R.; Mcintire M.S., 1977: Lead mercury and cadmium toxicity in children. Paediatrician 6(35): 204-225