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Electrocardiographic changes in dermatomyositis and polymyositis


, : Electrocardiographic changes in dermatomyositis and polymyositis. Revista Brasileira de Reumatologia 56(2): 95-100

Cardiac involvement is frequent in inflammatory myopathies. Electrocardiogram (ECG) may show evidence of this involvement and its changes should be well-known and described. Due to the lack of studies in the literature, we conducted an analysis of the ECG findings in patients with dermatomyositis (DM) and polymyositis (PM), comparing them with a control group. This cross-sectional study compared the ECG of 86 individuals with no rheumatic disorders (controls) with 112 patients (78 DM and 34 PM), during 2010-2013. The ECG findings between DM and PM were also compared. Demographic characteristics, comorbidities and ECG abnormalities were similar between controls and patients (p>0.05), except for a higher frequency of left ventricular hypertrophy (LVH) in patients (10.7% vs. 1.2%, p=0.008). Demographic characteristics, comorbidities, clinical and laboratory manifestations, were also similar between the groups PM and DM, except for the presence of cutaneous lesions only in DM. One-third of the patients had ECG abnormalities, which were more prevalent in PM than DM (50% vs. 24.4%, p=0.008). LVH, left atrial enlargement, rhythm and conduction abnormalities were more frequent in PM than DM (p<0.05 for all), especially the left anterior fascicular block. We showed distinct ECG changes between DM and PM and a higher frequency of LVH in patients compared to controls. Investigation of cardiac involvement should be considered even in asymptomatic patients, especially PM. Further studies are necessary in order to determine the correlation of ECG findings with other complementary tests, clinical manifestations, disease activity and progression to other cardiac diseases.

US$19.90

PMID: 27267520

DOI: 10.1016/j.rbre.2014.08.012


Other references

Scardi S.; Pandullo C.; Pivotti F.; Ceschia G.; Pollavini G., 1988: Individual responses to transdermal nitrates after chronic administration in angina pectoris. The aim of this study was to investigate whether, and to which extent, sustained treatment with transdermal nitroglycerin plasters may lead to the development of tolerance in patients with effort-induced angina pectoris. Ten patients, all men, mea...

Cénac, A.; Djibo, A.; Djangnikpo, L., 1993: Peripartum dilated cardiomyopathy. A model of multifactor disease?. The peripartum cardiomyopathy is a rare condition in Europe but a very frequent disease in Sahelian Africa. The risk factors are: heat, hard physical exertion during pregnancy, hypertension, sodium diet, ablutions with hot water during the postpar...

Gray, J.R., 2006: The use of B-type natriuretic peptide to diagnose congestive heart failure. This paper explains the background and current use of B-type natriuretic peptide (BNP) assays to differentiate congestive heart failure (CHF) from other causes of dyspnea. With a large and growing elderly population, CHF is being diagnosed much mo...

Gupta, V.K.; Gurcharan Singh; Garg, R.N., 1994: Effect of mulches on soil thermal regime and crop growth of mungbean (Vigna radiata L.) and mustard (Brassica carinata). In field trials in summer 1990 and rabi [winter] 1990/91 on sandy loam soil at New Delhi, the effects were studied of polyethylene mulch (black and transparent) or straw mulch placed between rows after sowing on soil temperature and yield of V. ra...

Trivedi A.; Schwab M.; Tustanoff E.R., 1986: Significance of phospholipid polar headgroups on yeast cytochrome c oxidase kinetics. Federation Proceedings 45(6): 1833

Bhargava, H.N.; Kumar, S., 1997: Sensitization to the locomotor stimulant activity of cocaine is associated with increases in nitric oxide synthase activity in brain regions and spinal cord of mice. Effects of multiple administrations of cocaine and subsequent cocaine withdrawal on the activity of nitric oxide synthase (NOS) in brain regions and spinal cord of male Swiss-Webster mice were determined. Chronic administration of cocaine resulted...

Wood, K.; Buttermann, G.; Butterman, G.; Mehbod, A.; Garvey, T.; Jhanjee, R.; Sechriest, V., 2003: Operative compared with nonoperative treatment of a thoracolumbar burst fracture without neurological deficit. A prospective, randomized study. To our knowledge, a prospective, randomized study comparing operative and nonoperative treatment of a thoracolumbar burst fracture in patients without a neurological deficit has never been performed. Our hypothesis was that operative treatment wou...

Imai T., 1991: Studies on the pigmentary selection and wound healing of neodymium yag contact laser irradiation. This study was made to observe the difference between the pigmented and non-pigmented areas of long-evans rats that were irradiated by Nd:YAG contact laser. The irradiation conditions were that the output power at the end of the hand-piece was set...

Gallucci, R.M.; Meadows, G.G., 1995: Ethanol consumption reduces the cytolytic activity of lymphokine-activated killer cells. Ethanol (20% w/v) given to female C57BL/6 mice in their drinking water reduces splenic natural killer (NK) cell cytolytic activity after 2, 4, and 10 weeks of consumption. This reduction is transient because the levels of NK cell cytotoxicity from...

Gute, B.D.; Basak, S.C., 2006: Optimal neighbor selection in molecular similarity: comparison of arbitrary versus tailored prediction spaces. Three classes of arbitrary quantitative molecular similarity analysis (QMSA) methods have been computed using atom pairs (APs), topological indices (TIs), and principal components (PCs) derived from topological indices. Tailored QMSA models have b...