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Epidemiology and cost implications of candidemia, a 6-year analysis from a developing country


, : Epidemiology and cost implications of candidemia, a 6-year analysis from a developing country. Mycoses (): -

NlmCategory="UNASSIGNED">Surveillance of candidemia is essential to monitor trends in species distribution and change in the incidence and antifungal resistance. In this study, we aimed to investigate prevalence, resistance rates, antifungal utilization and costs. A 6-year retrospective analysis of the data belonging to patients with candidemia hospitalized between 2010 and 2016 was performed. The annual usage of fluconazole and caspofungin and the usage of these antifungals in different units were described in defined daily doses (DDD) per 1000 patient days. In total, 351 patients of candidemia were included. Median age of the patients was 45 (0-88) and 55.1% of them were male. Overall, 48.1% of the candidemia episodes (169/351) were due to C. albicans, followed by C. parapsilosis (25.1%), C. glabrata (11.7%). Length of hospital stay was longer with a median of 20 days among patients with non-albicans candidemia. Presence of a central venous catheter was found to be an associated risk for candidemia caused by non-albicans strains. Annual incidence of candidemia increased from 0.10 to 0.30 cases/1000 patient days. Antifungal use was increased over years correlated with the cost paid for it. The policy against candidemia should be specified by each institution with respect to candidemia prevalence, resistance rates, antifungal use and costs.

US$19.90

PMID: 27862414

DOI: 10.1111/myc.12582


Other references

Baas, R.; Nijssen, H.M.C.; Van Den Berg, T.J.M.; Warmenhoven, M.G., 1995: Yield and quality of carnation and gerbera in a closed nutrient system as affected by sodium chloride. To study the consequences of NaCl-containing irrigation water in closed nutrient systems, effects of increasing NaCl concentrations up to 30 mM on yield and quality of spray carnation and gerbera were investigated. In carnation, salinity decreased...

Selimoğlu, M.Ayşe.; Ertekin, V.; Eren, S., 2005: Clinical quiz. Gamma-Gandy bodies. Journal of Pediatric Gastroenterology and Nutrition 40(4): 524-525

Dagenbach, H.; Schlenker, G., 1976: Dothichiza resistance of different Poplar varieties in the Reichenberg Populetum. During 1962-71, a Dothichiza populea epidemic spread through this Populetum (75 Populus clones and populations) in the Neckar Valley. Trees were observed for their resistance to attack: results are tabulated (in 6 groups of severity of attack) and...

Lill, J.; Bauer, L.A.; Horn, J.R.; Hansten, P.D., 2000: Cyclosporine-drug interactions and the influence of patient age. Cyclosporine-drug interactions in adult transplant patients and the impact of age were studied. The medical records of transplant patients receiving cyclosporine therapy were identified. Data on patient demographics, cyclosporine dosages, dosage f...

Ikemoto, S.; Miyake, B.; Yoshida, H.; Tomita, K., 1984: Transformation of blood group antigens and release of amino acids induced by dispase treatment. Nihon Hoigaku Zasshi 38(1): 1-4

Baden, R.; Rockstroh, Jürgen.K.; Buti, M., 2014: Natural history and management of hepatitis C: does sex play a role?. Hepatitis C virus infection is a disease that disproportionately affects men more than women. After initial HCV infection, women are more likely to clear the virus spontaneously. Women also have slower rates of liver disease progression than men i...

Mellies, J.; Wise, A.; Villarejo, M., 1995: Two different Escherichia coli proP promoters respond to osmotic and growth phase signals. proP of Escherichia coli encodes an active transport system for proline and glycine betaine which is activated by both hyperosmolarity and amino acid-limited growth. proP DNA sequences far upstream from the translational start site are strongly ho...

Kentsmith, D.K., 1982: Hostages and other prisoners of war. Military Medicine 147(11): 969-70, 972

Blizzard, T.A.; Mosley, R.T.; Birzin, E.T.; Chan, W.; Hammond, M.L., 2004: Comparison of 2-phenylspiroindenes and 2-phenylspiroindenediones as estrogen receptor ligands--modeling and binding data don't agree!. A series of 2-phenylspiroindenediones was prepared. The spiroindenediones were found to be less active than the corresponding spiroindenes as estrogen receptor ligands and failed to demonstrate the receptor subtype selectivity that had been antici...

Sharma, S.B.; Price, N.S.; Bridge, J., 1997: The past, present and future of plant nematology in International Agricultural Research Centres. This article reviews the plant parasitic nematodes of the major mandate crops of the International Agricultural Research Centres, which include 19 of the world's key staple crops such as rice, wheat, maize, potato, barley, root crops and grai...