+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Evaluation of cutaneous surface parameters in psoriatic patients

, : Evaluation of cutaneous surface parameters in psoriatic patients. Skin Research and Technology

The purpose of this study was to compare cutaneous surface parameters in lesional and non-lesional skin of psoriatic patients and in corresponding areas of control subjects. Sixty-six psoriatic patients (of any grade of severity, with or without arthritis, without any therapy other than systemic biologic drugs) and 28 healthy controls were enrolled in this observational, case-control study. Exclusion criteria were current or past sebo-psoriasis and seborrheic dermatitis, pustular or erithrodermic psoriasis; treatment with immune-suppressive agents, retinoids, or ultraviolet phototherapy in the last 6 months; topical treatment in the last 2 weeks. Corneometry, sebumetry, and pHmetry were evaluated on non-lesional skin of forehead, cheek, chin and volar region of forearm, and on a psoriatic plaque (on elbow or neighboring areas); in controls, the same areas were considered. Corneometry values were significantly lower in psoriatic plaques vs. elbows of controls. Sebumetry showed significantly higher values in non-lesional forearm skin and plaques of psoriatic patients vs. corresponding areas of controls. pH was significantly lower in all areas in psoriasis. No differences were found between patients treated or not with biologics and with or without arthritis. Evaluating surface skin parameters in psoriasis is useful to better understand the etiopathogenic mechanism and could suggest new therapeutic approaches.


PMID: 27270565

DOI: 10.1111/srt.12299

Other references

Mouton, C.; Reynolds, H.S.; Genco, R.J., 1980: Characterization of tufted streptococci isolated from the "corn cob" configuration of human dental plaque. Streptococci isolated from "corn cob" configurations of human dental plaque possess a polar fibrillar tuft extending 100 to 150 nm from one pole of the cell. The two strains studied were physiologically related to the Streptococcus sangu...

Mastandréa, Érika.Bergamini.; Lucchesi, Fátima.; Kitayama, M.Mayumi.Gomes.; Figueiredo, M.Stella.; Citero,, 2015: The relationship between genotype, psychiatric symptoms and quality of life in adult patients with sickle cell disease in São Paulo, Brazil: a cross-sectional study. Health-related quality of life (HRQoL) may be worsened in sickle cell patients due to the presence of psychiatric disorders. The aims of this study were to describe the psychiatric symptoms in Brazilian sickle cell patients and to evaluate the rel...

Kosmiderski S., 1968: Rubber latex in slide test for diagnosis of syphilis human. Polski Tygodnik Lekarski 23(43): 1639-1641

Farr, S.L.; Dietz, P.M.; Williams, J.R.; Gibbs, F.A.; Tregear, S., 2012: Depression screening and treatment among nonpregnant women of reproductive age in the United States, 1990-2010. Whether routine screening for depression among nonpregnant women of reproductive age improves identification and treatment of the disorder remains unclear. We conducted a systematic review of the literature to address 5 key questions specific to t...

Rastogi, A.; Sarkar, A.; Chakrabarty, D., 2017: Partial purification and identification of a metalloproteinase with anticoagulant activity from Rhizostoma pulmo (Barrel Jellyfish). Rhizostoma pulmo (Barrel Jellyfish) is one of the commonly found jellyfishes on the South-Goan coast of India. Here we present characterization of R. pulmo tentacle extract. The tentacle extracts were found to be capable of affecting the hemostat...

Martin C.J.; Dantas R.; Dodds W.J.; Dent J.; Layman R.D., 1989: Relaxation of the diaphragmatic hiatus is essential for gastro esophageal reflux in the dog. Australian & New Zealand Journal of Medicine 19(5 SUPPL 1): 595

Smiley, K.A.; Lieberman, E.M., 1980: Electrophysiological and pharmacological properties of glial cells associated with the medial giant axon of the crayfish with implications four neuron-glial cell interactions. Schwann-like glial cells surrounding the medial giant axon of the crayfish (Procambarus clarkii) were impaled with glass microelectrodes to study their responses to cholinomimetics, cholinergic receptor blockers and ouabain. Axon electrical proper...

Cobleigh M.A., 1991: Chemotherapy in association with radiotherapy as adjuncts to surgery for locally advanced nonmetastatic cancer of the breast. Economou, S G , T R Witt, D J Deziel, T J Saclarides, E D Staren And S D Bines Adjuncts to Cancer Surgery Xxv+703p Lea And Febiger: Philadelphia, Pennsylvania, Usa; London, England, Uk Illus 540-544

LoCicero, J.; Xu, X.; Zhang, L., 1999: Heat shock protein suppresses the senescent lung cytokine response to acute endotoxemia. Annals of Thoracic Surgery 68(4): 1150-1153

Flomerfelt, F.A.; Gress, R.E., 2016: Analysis of Cell Proliferation and Homeostasis Using EdU Labeling. Determination of cellular proliferation and population turnover is an important tool for research on lymphoid cell function. Historically this has been done using radiolabeled nucleotides or nucleoside analogs, such as BrdU (5-bromo-2-deoxyuridine...