geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Five in one therapy for graded treatment of haemophilic arthritis


, : Five in one therapy for graded treatment of haemophilic arthritis. Haemophilia

Haemophilic arthritis is the most universal clinical appearance of haemophilia. Treatment of this disease has become an important and difficult issue worldwide until recently. To investigate the efficacy and safety of five in one therapy for graded treatment of haemophilic arthritis. Haemophilic arthritis was classified into grades I-IV according to severity and the standards of De Palma and Cotler. Under no application of FVIII/FIX replacement therapy state, the effect of five in one therapy (intra-articular cavity drug injection, oral drug preparation, physiotherapy, and prevention of haemorrhage and infection evoked by puncture) was observed in 1527 affected joints of 750 cases of haemophilic arthritis. After 20 days treatment, all grade I and II, 94.98% of grade III and 56.16% of grade IV affected joints were completely relieved; 5.02% of grade III and 41.47% of grade IV affected joints were basically relieved; and 2.38% of grade IV were partially relieved. This resulted in short-term complete and basic relief of 98.56% (1505/1527) of all affected joints. After follow-up of 1-6 years, 86.97% of the affected joints were completely relieved, without any adverse reaction or complication. The results suggest that five in one therapy is safe and effective for treatment of haemophilic arthritis, and provides a convenient, cost-effective way of preventing and treating deformity caused by haemophilic arthritis.

US$19.90

PMID: 26178974

DOI: 10.1111/hae.12746


Other references

Fernández-Guarino, M.; Harto, A.; Pérez-García, B.; Montull, C.; D.L.s Heras, E.; Jaén, P., 2011: Plaque-phase mycosis fungoides treated with photodynamic therapy: results from 12 patients. Recent years have seen an increase in the off-label use of photodynamic therapy for the treatment of a variety of skin diseases. Plaque-phase mycosis fungoides is among the most promising possibilities for the use of this treatment. To evaluate th...

Zarski, S.; Styczyński, T., 1978: Varicosity of the lower part of the vertebral canal. In a group of 300 patients with the diagnosis of lumbar nucleus pulposus prolapse treated surgically the authors found in 4 cases not the expected prolapse but varicose blood vessels surrounding the nerve roots and immobilizing them in adhesions....

Chen, M.J.; Nguyen, T.V.; Pike, C.J.; Russo Neustadt, A., 2003: Norepinephrine enhances BDNF expression in cultured hippocampal neurons. Brain-derived neurotrophic factor (BDNF) is well known for its role in neuronal survival, learning and memory, and the amelioration of mood disorders. Antidepressants, which increase the levels of circulating norepinephrine (NE) and serotonin (5-H...

Unnewehr, M.; Friederichs, H.; Bartsch, P.; Schaaf, B., 2016: High Diagnostic Value of a New Real-Time Pneumocystis PCR from Bronchoalveolar Lavage in a Real-Life Clinical Setting. To diagnose Pneumocystis jirovecii pneumonia (PCP), PCR testing in bronchoalveolar lavage (BAL) fluid has recently become an alternative to immunofluorescence testing (IFT); however, its diagnostic accuracy is less clear. To analyze the diagnostic...

Anonymous, 2012: Weather records due to climate change A game with loaded dice. The past decade has been one of unprecedented weather extremes. Scientists of the Potsdam Institute for Climate Impact Research in Germany argue that the high incidence of extremes is not merely accidental. From the many single events a pattern em...

Shi, L-Bo.; Hou, Y-Dong.; Shen, J-Ying.; Wang, G-Long., 2015: Effects of tobacco on rat gingival fibroblats attaching to titanium. The study was designed to observe the effects of the smokeless tobacco extract(ST) on the attachment,morphology,structure and proliferation of rat gingival fibroblasts(RGFs) to titanium in vitro. RGFs were obtained from explants of rat normal ging...

Arganaraz, Fernando Mayorga, 1998: Corrective surgery for myopia, hypermetropia and astigmatism. Correction of refractive errors with excimer laser therapy, is the procedure of choice in the modern ophtalmology. Results of this type of surgery are predictible and also very accurate, specially in moderate and low myopias. Hypermetropia and upp...

Bruder, M.; Schuss, P.; Berkefeld, J.; Wagner, M.; Vatter, H.; Seifert, V.; Güresir, E., 2015: Subarachnoid hemorrhage and intracerebral hematoma caused by aneurysms of the anterior circulation: influence of hematoma localization on outcome. Additional space-occupying intracerebral hematoma (ICH) in patients suffering from subarachnoid hemorrhage (SAH) is a known predictor for poor outcome. Emergent clot evacuation might be mandatory. However, data concerning the influence of ICH loca...

Frantsesson Y.V., 1968: Conjugation of carbonatite and kimberlite of the Siberian platform. English translation of Russian article (see this Bibliography Vol. 33, No. 8, 09 E69-15993).

Hedges, J.F.; Balasuriya, U.B.; MacLachlan, N.J., 1999: The open reading frame 3 of equine arteritis virus encodes an immunogenic glycosylated, integral membrane protein. Stallions repeatedly immunized with a modified live equine arteritis virus (EAV) vaccine were positive for serum antibodies specific for the glycosylated membrane protein, GP3, which is putatively encoded by open reading frame 3. Results indicate...