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Fungal fermentation of lignocellulosic biomass for itaconic and fumaric acid production

, : Fungal fermentation of lignocellulosic biomass for itaconic and fumaric acid production. Journal of Microbiology and Biotechnology (): -

NlmCategory="UNASSIGNED">The production of high-value chemicals from natural resources as alternative of petroleum-based products is currently expanding in parallel with biorefinery. The use of lignocellulosic biomass as raw material is promising to achieve economic and environmental sustainability. Filamentous fungi, particularly Aspergillus species, are already used industrially to produce organic acid as well as many enzymes. The production of lignocellulose degrading enzymes opens the possibility for direct fungal fermentation towards organic acids as itaconic and fumaric acids. These acids have wide-range applications and potentially addressable markets as platform chemicals. However, current technologies for the production of these compounds are mostly based on submerged fermentation. This work showed the capacity of two Aspergillus species (A. terreus and A. oryzae) to yield both acids by solid-state fermentation and simultaneous saccharification and fermentation. FA was optimally produced at by A. oryzae in simultaneous saccharification and fermentation (0.54 mg/g wheat bran). The yield of 0.11 mg IA/ g biomass by A. oryzae is the highest reported in the literature for simultaneous solid-state fermentation without sugar supplements.


PMID: 27666988

DOI: 10.4014/jmb.1607.07057

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