geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Immune-mediated myelopathies


, : Immune-mediated myelopathies. Continuum 21(1 Spinal Cord Disorders): 121-131

This article presents data about inflammatory myelopathies, also referred to as transverse myelitis. While the idiopathic form of this condition is rare, the prevalence of transverse myelitis is relatively common when including all of the secondary causes, such as multiple sclerosis (MS). Thus, clinicians and researchers should be familiar with the presentations, diagnostic algorithms, treatment options, and long-term symptom management for patients with transverse myelitis. This review presents data about the idiopathic and secondary forms of transverse myelitis. As research has expanded, the presentations of transverse myelitis have been clarified and the secondary causes explored. With the identification of the aquaporin-4 (AQP4) antibody, more patients with transverse myelitis have been categorized as having neuromyelitis optica (NMO), and more variable presentations have been published. A growing experience with various treatment options has expanded the therapeutic approaches to acute inflammatory myelopathies beyond standard corticosteroid intervention regimens. Transverse myelitis can occur in isolation or as part of a larger systemic condition. An empiric approach to patient evaluation can accelerate diagnosis of secondary conditions. Mounting evidence suggests that an aggressive approach to therapy can improve patient outcomes, but large-scale prospective trials are lacking.

US$19.90

PMID: 25651221

DOI: 10.1212/01.CON.0000461088.63994.a2


Other references

Shah, A.; Gnoj, J.; Fisher, V.J., 1975: Complications of selective coronary arteriography by the Judkins technique and their prevention. Complications encountered during 351 selective coronary artery and coronary artery bypass examinations performed by the Judkins technique are reviewed. The over-all incidence of cardiac and peripheral vascular complications was 3.13 per cent. The...

Anonymous, 2013: The Impact of Relative Poverty on Norwegian Adolescentsamp;amp;#8217; Subjective Health A Causal Analysis with Propensity Score Matching. Studies have revealed that relative poverty is associated with ill health, but the interpretations of this correlation vary. This article asks whether relative poverty among Norwegian adolescents is causally related to poor subjective health, i.e....

Jorgensen M.B.; Bretlau P.; Ebert U.; Hentzer E., 1970: Oto pathological examination of oto sclerosis and neurinomata of the acoustic nerve. Acta Oto-Laryngologica Supplement 263: 10

Schug, A.; Weigt, M.; Onuchic, Jé.N.; Hwa, T.; Szurmant, H., 2010: High-resolution protein complexes from integrating genomic information with molecular simulation. Bacteria use two-component signal transduction systems (TCS) extensively to sense and react to external stimuli. In these, a membrane-bound sensor histidine kinase (SK) autophosphorylates in response to an environmental stimulus and transfers the...

Goode, R.L., 1968: Mattress suture otopasty. Transactions - American Academy of Ophthalmology and Otolaryngology. American Academy of Ophthalmology and Otolaryngology 72(3): 427-434

Nemtsov,D.A.; Zabaniotou,A., 2008: Mathematical modelling and simulation approaches of agricultural residues air gasification in a bubbling fluidized bed reactor. Agricultural residues (agro-biomass) can produce energy by thermochemical conversion. Gasification is becoming one of the best clean technologies for power production. Thermochemical process of gasification sets free the solid fuel inherent energy...

Vainshtein, V.G., 1964: Homoplasty Of The Proximal Portion Of The Femur. Vestnik Khirurgii Imeni I. I. Grekova 93: 75-78

Pinkham, C.B., 1937: Concerning the scope of chiropractic. California and Western Medicine 47(3): 211-211

Beiguelman, B.; Ramalho, A.S.; Arena, J.F.; Garlipp, C.R., 1977: Isoniazid acetylation among Brazilian Caucasoids and Negroids with pulmonary tuberculosis. Revista Paulista de Medicina 89(1-2): 12-15

Ambroise-Thomas, P., 1983: Vaccination against malaria. Theoretical principles and practical perspectives. Therapeutische Umschau. Revue Therapeutique 40(3): 248-252