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In experimental chronic kidney disease or cancer, parathyroid hormone is a novel mediator of cachexia

, : In experimental chronic kidney disease or cancer, parathyroid hormone is a novel mediator of cachexia. Kidney International 89(5): 973-975

Hyperparathyroidism plays a central role in the disordered bone mineral metabolism of chronic kidney disease, and has been associated with increased cardiovascular morbidity and mortality in that setting. A recent study suggests a novel role for parathyroid hormone and its receptor in muscle wasting and cachexia occurring in advanced chronic kidney disease.


PMID: 27083271

DOI: 10.1016/j.kint.2016.03.003

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