+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Measuring Intraocular Pressure in Patients With Keratoconus With and Without Intrastromal Corneal Ring Segments

, : Measuring Intraocular Pressure in Patients With Keratoconus With and Without Intrastromal Corneal Ring Segments. Journal of Glaucoma (): -

To compare intraocular pressure (IOP) measurements made using 5 tonometers in keratoconic eyes with and without intrastromal corneal ring segments. This was an observational case series study. A total of 147 eyes of 147 patients with keratoconus, 74 of which had undergone corneal ring segment placement, were prospectively evaluated. IOP was measured using the tonometers Tonopen XL, Pascal dynamic contour tonometer, iCare Pro, ocular response analyzer (ORA), and Goldmann applanation (GAT) in random order. The Bland-Altman method was used to examine interinstrument agreement. Effects on readings of central corneal thickness, corneal curvature, and corneal astigmatism were assessed by multivariate regression analysis. Smallest mean IOP differences with GAT measurements in eyes without and with ring segments, respectively, were detected for iCare Pro [0.2 (2.9) mm Hg and 0.4 (3.0) mm Hg, P=0.914] and greatest differences for ORA Goldmann-correlated IOP [5.8 (3.3) mm Hg and 6.0 (3.1) mm Hg, P=0.363]. Best agreement with GAT was shown by iCare Pro (ICC=0.829; 95% CI, 0.721-0.896) and worse agreement by ORA corneal-compensated IOP (ICC=-0.145; 95% CI, -0.826 to 0.283). All but the dynamic contour tonometer readings were influenced by central corneal thickness, yet these measurements were affected by the presence of ring segments (P=0.017) and corneal astigmatism (P=0.030). Corneal curvature only affected ORA Goldmann-correlated IOP (P=0.029). All 5 tonometers provided reliable IOP readings in the keratoconic eyes regardless of the presence of corneal ring segments. iCare Pro readings were most consistent with GAT, whereas ORA readings were least consistent with this reference standard.


PMID: 27661992

DOI: 10.1097/IJG.0000000000000549

Other references

Aminev, A.G.; Polekhin, S.V.; Andreev, V.G.; Gusev, A.A., 1998: Detection and genotyping of Marek's disease virus by polymerase chain reaction. New pathogenic isolates of type 1 Marek's disease virus (MDV) were identified in various regions of Russia using polymerase chain reaction. Nucleotide sequence of glycoprotein B (gB) 13 gene region, the most variable region with respect to in...

Penhoat, Mélanie.; Saraux, A.; L.G.ff, Bît.; Augereau, P.; Maugars, Y.; Berthelot, J-Marie., 2014: High pain catastrophizing scores in one-fourth of patients on biotherapy for spondylarthritis or rheumatoid arthritis. To measure catastrophizing scores in patients on biotherapy for spondyloarthritis (SpA) or rheumatoid arthritis (RA). The first 140 outpatients or day-hospital patients seen at a teaching hospital rheumatology department for biotherapy administrat...

Straits, T.D.; Obecny, A.D.; Greene, K.R., 1996: Hand grip for use with syringe. Official Gazette of the United States Patent & Trademark Office Patents 1190(2): 1110, Sept 10

Turkmen, C.; Ozturk, S.; Unal, S.N.; Zulfikar, B.; Taser, O.; Sanli, Y.; Cefle, K.; Kilicoglu, O.; Palanduz, S., 2007: The genotoxic effects in lymphocyte cultures of children treated with radiosynovectomy by using yttrium-90 citrate colloid. The aim of this study was to investigate the genotoxic effect on the peripheral blood lymphocytes potentially induced by yttrium-90 citrate colloid (Y-90) in children who were undergoing radiosynovectomy for hemophilic synovitis, using chromosoma...

Bird, R.C.; Pai, S.R.; Wu, G.; Su, S.P., 1992: Regulation of G-1 phase Overexpression of c-fos induces overexpression of the tumour suppressor gene RB-105. Cell Proliferation 25(5): 462

Yu, L.X.; Amidon, G.; Khan, M.A.; Hoag, S.W.; Polli, J.; Raju, G.K.; Woodcock, J., 2015: Understanding pharmaceutical quality by design. This review further clarifies the concept of pharmaceutical quality by design (QbD) and describes its objectives. QbD elements include the following: (1) a quality target product profile (QTPP) that identifies the critical quality attributes (CQAs...

Hart, P.M.D'a., 1937: The prevention of pulmonary tuberculosis among adults in England in the past and in the future. The downward trend of pulmonary tuber-culosis has, 011 the whole, been the result of social measures not specifically directed against the disease. One of the factors has probably been improved diet. The new concept of optimal health and optimal d...

Akavia N.; Strack D., 1980: High performance liquid chromatography of antho cyanidins as a new approach to study flower pigment genetics. The method allows rapid screening and accurate quantification of anthocyanidins with the aid of HPLC [high performance liquid chromatography]. Using a linear gradient in 40 min from 20 to 40% of solvent B (1.5% phosphoric acid -20% acetic acid -25...

Kabashea G.N., 1973: Conformation of substituted benzylidene and iso propylidene nucleosides. Tetrahedron: 2277-2283

Goel, A.; Dalela, D., 2016: Mechanical suction for clot evacuation: experience with "suction bridge" for safe and effective clot removal. To present the experience with the use of a "suction bridge" for removal of bladder clots. In all patients presenting with bladder clots, mechanical suction was done using a "suction bridge". This bridge has a luer lock that is...