geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Multiple sclerosis following anti-tumor necrosis factor-alpha therapy for psoriasis: first case in Italy? Case report and review of the literature


, : Multiple sclerosis following anti-tumor necrosis factor-alpha therapy for psoriasis: first case in Italy? Case report and review of the literature. Giornale Italiano di Dermatologia E Venereologia

NlmCategory="UNASSIGNED">The use of Tumor Necrosis Factor alpha (TNF--α) antagonists has profoundly improved clinical management of psoriasis and other inflammatory diseases, but acute and chronic adverse reactions, including demyelination, are becoming increasingly recognized. We reported a case of multiple sclerosis in a 48--year--old Italian man with plaque psoriasis treated with etanercept. Through a literature review, we found a total of 35 psoriatic patients, including our case, in whom a demyelinating disease developed in course of TNF--α antagonists therapy. Since neurological disorders are rarely associated with the use of anti--TNF--α therapy in psoriatic patients, but have severe side effects, physicians should screen patients before starting therapy, excluding a positive anamnesis for demyelinating disease;; if patients receiving anti--TNF--α drugs develop new or unusual neurological symptoms, the anti--TNF--α drug should be stopped and patient should be properly examined. Furthermore, therapies for demyelinating diseases that could exacerbate psoriasis manifestations should be carefully avoided.

US$29.90

PMID: 25692775


Other references

Lo, N.; Paraskevopoulos, C.; Bourtzis, K.; O'Neill, S.L.; Werren, J.H.; Bordenstein, S.R.; Bandi, C., 2007: Taxonomic status of the intracellular bacterium Wolbachia pipientis. Wolbachia pipientis is a maternally inherited, intracellular bacterium found in more than 20 % of all insects, as well as numerous other arthropods and filarial nematodes. It has been the subject of a growing number of studies in recent decades, b...

Carlson, L.A.; Rossner, S., 1972: A methodological study of an intravenous fat tolerance test with IntralipidR emulsion. The fat emulsion Intralipid was used as a tracer for plasma triglyceride in an intravenous fat tolerance test. A single intravenous injection of the emulsion was given and turbidity of blood samples taken during the next 40 min was estimated nephe...

Ferreira, L.Souza.Dos.Santos.; Pereira, C.Borges.; Rossini, S.; Kanashiro, A.Mizuta.Kozoroski.; Adda, C.Cristina.; Scaff, M., 2010: Psychological assessment in patients with phobic postural vertigo. Phobic postural vertigo (PPV) is a frequent diagnosis which can be challenging to treat. To investigate the presence of psychiatric disturbances in patients with PPV; to assess the psychological status of patients using adaptive diagnosis; to veri...

Piffault, C.; Duhamel, J., 1962: On the balance of the mandible. Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales 156: 2031-2032

Taylor, P.J.; Russ-Eft, D.F.; Chan, D.W.L., 2005: A meta-analytic review of behavior modeling training. A meta-analysis of 117 studies evaluated the effects of behavior modeling training (BMT) on 6 training outcomes, across characteristics of training design. BMT effects were largest for learning outcomes, smaller for job behavior, and smaller still...

Friedman, J., 1967: Distal occlusions. Revista Brasileira de Odontologia 25(146): 196-211

Katafuchi, T.; Kondo, T.; Take, S.; Yoshimura, M., 2005: Enhanced expression of brain interferon-alpha and serotonin transporter in immunologically induced fatigue in rats. Immunologically induced fatigue was induced in rats by intraperitoneal injection of a synthetic double-stranded RNA, polyriboinosinic : polyribocytidylic acid (poly I:C). An injection of poly I:C (3 mg/kg) decreased the daily amounts of spontaneou...

Phocas, F.; Belloc, C.; Bidanel, J.; Delaby, L.; Dourmad, J.Y.; Dumont, B.; Ezanno, P.; Fortun-Lamothe, L.; Foucras, G.; Frappat, B.; González-García, E.; Hazard, D.; Larzul, C.; Lubac, S.; Mignon-Grasteau, S.; Moreno, C.R.; Tixier-Boichard, M.; Brochard, M., 2016: Review: Towards the agroecological management of ruminants, pigs and poultry through the development of sustainable breeding programmes: I-selection goals and criteria. NlmCategory="UNASSIGNED">Agroecology uses natural processes and local resources rather than chemical inputs to ensure production while limiting the environmental footprint of livestock and crop production systems. Selecting to achieve...

Kamzolkina O.V.; Mozhina I.A.; Grube E.T.; Safrai A.I.; D'yakov Y.T., 1992: Method for obtaining self sterile clones of cultivated mushroom agaricus bisporus lange imbach. The regime of spores centrifugation in saccharose density gradients (GDS) is described, which allows to select fraction, enriched with uninuclear A. bisporus spores. Monospore cultures, obtained from this fraction, consist of both fast mycelium gr...

Suganthy, N.; Devi, K.Pandima.; Nabavi, S.Fazel.; Braidy, N.; Nabavi, S.Mohammad., 2016: Bioactive effects of quercetin in the central nervous system: Focusing on the mechanisms of actions. NlmCategory="UNASSIGNED">Quercetin, a ubiquitous flavonoid that is widely distributed in plants is classified as a cognitive enhancer in traditional and oriental medicine. The protective effects of quercetin for the treatment of neuro...