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Older Rural- and Urban-Dwelling Appalachian Adults With Mild Cognitive Impairment


, : Older Rural- and Urban-Dwelling Appalachian Adults With Mild Cognitive Impairment. Journal of Rural Health

Mild cognitive impairment (MCI) is a well-recognized risk state for Alzheimer's disease and other dementias. MCI is rapidly increasing among older adults in general and has not yet been examined in older adults within the Appalachian region. Our objective was to compare MCI symptom severity among older rural and urban Appalachian adults with MCI at an initial neuropsychological testing visit. A cross-sectional, descriptive study of older Appalachian adults with MCI was conducted using data from the National Alzheimer's Coordinating Center Uniform Data Set. Symptom severity was conceptualized as neuropsychological composite scores across 4 cognitive domains and Clinical Dementia Rating-Sum of Boxes (CDR-SOB) score. For group comparisons, MANCOVA was used for cognitive domains and ANCOVA for CDR-SOB. The sample (N = 289) was about half male (54.3%), predominantly white (91.7%), and living with others (83.5%), with a mean (±SD) 74.6 ± 6.2 years of age and 15.4 ± 3.0 years of education. Rural and urban groups differed significantly in years since onset of cognitive symptoms (2.98 ± 1.91 in rural and 3.89 ± 2.70 in urban adults, t[260] = -2.23, P = .03), but they did not differ across sociodemographic features or comorbid conditions. Rural and urban participants were similar across the 4 cognitive domains and CDR-SOB (P ≥ .05). No differences were found between rural and urban Appalachian residents on MCI symptom severity. However, urban residents reported a longer time lapse from symptom identification to diagnosis than their rural counterparts. Future studies using more representative population samples of Appalachian and non-Appalachian adults will provide an important next step to identifying disparate cognitive health outcomes in this traditionally underserved region.

US$19.90

PMID: 27509183

DOI: 10.1111/jrh.12189


Other references

Natsume, M., 2001: Teaching employees. I explained stress education for employees around the following four points based on Guidelines for Mental Health Promotion at the Workplace. That is, understanding to employee's stress, the necessity for self-care, awareness of their stress...

Francois, J.; Jadin, J.; Wery, M.; Vandecasteele, J., 1963: Experimental Study Of The Treatment Of Toxoplasmosis. Bulletin de L'academie Royale de Medecine de Belgique 3: 459-485

Swartling, F.J.; Čančer, M.; Frantz, A.; Weishaupt, H.; Persson, A.I., 2015: Deregulated proliferation and differentiation in brain tumors. Neurogenesis, the generation of new neurons, is deregulated in neural stem cell (NSC)- and progenitor-derived murine models of malignant medulloblastoma and glioma, the most common brain tumors of children and adults, respectively. Molecular chara...

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Reveal, Jl, 1992: Proposal to conserve 7759 Crescentia (Bignoniaceae) with a conserved type. Taxon 41(1): 145-148

Cao, B.; Shi, Q.; Wang, W., 2015: Higher expression of SIRT1 induced resistance of esophageal squamous cell carcinoma cells to cisplatin. High expression of Sirtuin type 1 (SIRT1) exists in some cancer cells. However, it is still unclear whether SIRT1 affects the sensitivity of esophageal cancer cells to cisplatin. This study was designed to explore the relationship between SIRT1 ex...

Fontinha, S.; Jardim, R., 1999: Notes on vascular flora of Porto Santo's islets. For the islets of Porto Santo, Portugal, 94 taxa of vascular plants were surveyed, including 14 Madeiran endemics, with an exclusive species for Porto Santo (Lotus loweanus Webb) and 10 Macaronesian endemics. The percentage of endemic species was...

Lowe, W.H.; Nislow, K.H.; Bolger, D.T., 2004: Stage-specific and interactive effects of sedimentation and trout on a headwater stream salamander. In species with complex life cycles, stage-specific effects of environmental conditions combine with factors regulating stage-specific recruitment to determine population-level response to habitat disturbance. The abundance of the stream salamande...

Beberstein, H.H., 1951: Myxedema tuberosum circumscriptum of the legs. A.M.A. Archives of Dermatology and Syphilology 63(5): 649-650