geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Predictors of treatment with dialysis modalities in observational studies for comparative effectiveness research


, : Predictors of treatment with dialysis modalities in observational studies for comparative effectiveness research. Nephrology, Dialysis, Transplantation 30(7): 1208-1217

The Institute of Medicine has identified the comparative effectiveness of renal replacement therapies as a kidney-related topic among the top 100 national priorities. Given the importance of ensuring internal and external validity, the goal of this study was to identify potential sources of bias in observational studies that compare outcomes with different dialysis modalities. This observational cohort study used data from the electronic medical records of all patients that started maintenance dialysis in the calendar years 2007-2011 and underwent treatment for at least 60 days in any of the 2217 facilities operated by DaVita Inc. Each patient was assigned one of six dialysis modalities for each 91-day period from the date of first dialysis (thrice weekly in-center hemodialysis (HD), peritoneal dialysis (PD), less-frequent HD, home HD, frequent HD and nocturnal in-center HD). Of the 162 644 patients, 18% underwent treatment with a modality other than HD for at least one 91-day period. Except for PD, patients started treatment with alternative modalities after variable lengths of treatment with HD; the time until a change in modality was shortest for less-frequent HD (median time = 6 months) and longest for frequent HD (median time = 15 months). Between 30 and 78% of patients transferred to another dialysis facility prior to change in modality. Finally, there were significant differences in baseline and time-varying clinical characteristics associated with dialysis modality. This analysis identified numerous potential sources of bias in studies of the comparative effectiveness of dialysis modalities.

US$19.90

PMID: 25883196

DOI: 10.1093/ndt/gfv097


Other references

Jillson, O.F.; Buckley, W.R., 1951: Fungous disease in man acquired from cattle and horses (due to Trichophyton faviforme). The infection of man by the cattle ringworm fungus, T. faviforme, after contact with diseased cattle and horses is of frequent occurrence and in this well-illustrated article the authors describe the symptomatology of the condition. They distingui...

J.S.u an; J.Q.ang, 1997: Discovery of a new pterosaur in western Liaoning, China. The pterosaur from the Yixian Formation in Beipiao, Liaoning Province, is characterized by the medium-sized individual, short tail, presence of the gastralia, strong forelimbs, radius and ulna longer than wing-metacarpal, extremely narrow and elon...

Saboiev, S.S.; Mastonshoeva-Kh, S., 1991: Resources of glycyrrhiza uralensis fish. and glycyrrhiza glabra l. in gorno badakhshan. The resources of G. uralensis and G. glabra were evaluated in 1987-1989 to determine prospects for harvesting roots of these valuable medicinal plants as raw materials for pharmaceutical industry. It was found that the region possesses G. uralensi...

Ikegaya, H.; Saka, K.; Sakurada, K.; Nakamura, M.; Yoshida, K-ichi., 2006: A case of sudden death after intramuscular injection of butylscopolamine bromide. A 40-year-old man experienced cardiopulmonary arrest after intramuscular injection of 20 mg of butylscopolamine bromide. No pathological changes were found at autopsy, and 1.19 mu g/mL of butylscopolamine bromide was detected in his serum. Since h...

Terada H.; Shiire Y.; Koizumi K.; Aburano T.; Tonami N.; Hisada K I., 1988: Scintigraphy with indium 111 labeled leukocytes simplified procedure for labeling. To utilize 111In leukocytes in a routine work, simplified procedure for sterile leukocytes preparation and labeling with water soluble oxine sulfate was performed. Viability and chemotaxis of leukocytes were maintained during separation and labeli...

Peng ZhiLi; Jiang ZhuoQin; H.J.eYi (), 2008: The analysis of use of food additives in milk beverages in Guangzhou City in 2005-2006. Milk beverages produced in Guangzhou City, Guangdong Province, China during 2005-2006 were examined for the levels of 10 food additives. Of the milk samples examined, 0.54% showed overdose levels of food additives. Sorbic acid was present at overd...

Sol'skiĭ, I.P.; Chernykh, V.L.; Vasil'eva, I.O.; Getman, I.E.; Starchenko, M.L., 1975: Modern data on extrauterine pregnancy. Pediatriia Akusherstvo i Ginekologiia: 47-49

King-Schultz, L.W.; Orvidas, L.J.; Mannenbach, M.S., 2016: Stridor is not always croup. Respiratory distress and stridor are common presenting symptoms for children in the emergency department. Most of these children will have common illnesses such as bronchiolitis or croup. Clinicians, however, must maintain a broad differential dia...

Ishikawa S.; Katakura K.; Ogawa T., 1989: Ultrasonic doppler blood flow meter us patent 4809703 march 7 1989. Official Gazette of the United States Patent & Trademark Office Patents 1100(1): 129

Lew, 1998: Mapping fungal ion channel locations. Ion channel mapping techniques are described and the results for two fungal organisms, Saprolegnia ferax and Neurospora crassa, are presented. In these species, two channel types have been characterized, stretch-activated channels exhibiting signi...