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Primary endoscopic therapies for obesity and metabolic diseases


, : Primary endoscopic therapies for obesity and metabolic diseases. Current Opinion in Gastroenterology 31(5): 351-358

Endoscopic approaches to obesity may help fulfill the unmet need of over half the US adult population who would benefit from therapy for obesity but are not receiving it. Endoluminal approaches have the potential to be more efficacious than antiobesity medications and have a lower risk-cost profile compared with bariatric surgery. This review outlines the current state of primary endoscopic weight loss and metabolic therapies and sheds light on the challenges faced toward making endoscopic bariatric therapies 'ready for prime time'. Endoscopic approaches to obesity are being increasingly modeled on the proposed mechanisms contributing to the benefits of bariatric surgery.Therapies targeted at the stomach induce weight loss with only a proportional benefit to underlying metabolic disorders.Therapies targeting the proximal small bowel appear to modulate various neurohormonal pathways resulting in an improvement in metabolic profile in excess to that accounted for by weight loss itself. Rigorous scientific assessment of endoscopic approaches to obesity is necessary to allow its integration into the treatment algorithm of obesity. The endoscopic armamentarium against obesity continues to evolve with the endoscopist poised to be a key player in the management of this disease. http://links.lww.com/COG/A12.

US$19.90

PMID: 26154430

DOI: 10.1097/MOG.0000000000000203


Other references

Nielsen, N.Munk.; Hansen, A.Vinkel.; Simonsen, J.; Hviid, A., 2011: Prenatal stress and risk of infectious diseases in offspring. Animal studies have suggested that prenatal stress could affect the immune system of the offspring. In a nation-wide cohort of all Danish children born from 1977 to 24, the authors examined the association between prenatal stress, defined as mater...

McELIN.T.W.; MUSSEY.R.D.; WATKINS.C.H., 1950: Splenectomy during pregnancy, with a report of 5 cases and review of the literature. American Journal of Obstetrics and Gynecology 59(5): 1036-1044

Sidhu, M.; Sinuraya, Z.; Hasyim, A., 2004: Yield responses of young mature oil palms to NPK fertiliser application on loamy sand in Riau Province, Indonesia. A study was conducted during 1999-2003 to determine the early responses of young mature oil palms [Elaeis guineensis] grown in Indonesia to various combinations of NPK fertilizers (N at 2.0 and 3.0 kg palm-1 year-1, P at 2.0 and 3.0 kg palm-1 year...

Briere Peter R.; Smith Thomas J.I.I.I.; Foster Ann M.; Coffin Alisa W.; Rutchey Ken; Jones John W.; Van Arsdall Carson; Perry William B., 2003: Development of digital aerial photography archives for the greater Everglades of South Florida. Pages 504-505 2003

Das, R.; McNary, J.; Fitzsimmons, K.; Dobraca, D.; Cummings, K.; Mohle-Boetani, J.; Wheeler, C.; McDowell, A.; Iossifova, Y.; Bailey, R.; Kreiss, K.; Materna, B., 2012: Occupational coccidioidomycosis in California: outbreak investigation, respirator recommendations, and surveillance findings. To describe the investigation of a 2007 occupational coccidioidomycosis outbreak in California, recommend prevention measures, and assess statewide disease burden. We evaluated the worksite, observed work practices, interviewed the workers and emp...

Lampert, W.; Muck, P., 1985: Multiple aspects of food limitation in zooplankton communities: the Daphnia-Eudiaptomus example. Advances in Limnology, 21: 311-322

Willis J.V.; Kendall M.J.; Jack D.B., 1981: The influence of food on the absorption of diclofenac after single and multiple oral doses. A single dose of enteric-coated diclofenac [antiinflammatory analgesic] sodium was taken fasting and immediately after a standard breakfast by 12 healthy volunteers. A considerable delay in the onset of absorption was observed, non-fasting, varyin...

Marquez, C.A.; Michelis, A. de; Giner, S.A., 2006: Drying kinetics of rose hip fruits (Rosa eglanteria L.). Simulation of dehydration in beds for food particles demand long computing times. So, models for equipment design should be as simple as possible. An equipment with particulate material can be visualised as formed by a number of beds of given dept...

Ennew, C.T.; Ingersent, K.A.; Rayner, A.J., 1986: A statistical digest of UK and EEC production, utilisation and trade in sugar and potatoes, 1973-84. Divided into two sections, the first summarizes statistical factual information on the pattern of sugar production, utilization and trade since EC enlargement in 1973 and highlights the major trends both in the UK and the EC(9) as a whole. The sec...

Petrovics, G.; Zhang, W.; Makarem, M.; Street, J.P.; Connelly, R.; Sesterhenn, I.A.; Sun, L.; Moul, J.W.; Srivastava, S., 2003: PCGEM1, a prostate specific gene promoting cell growth, is overexpressed in prostate cancer cells of African Americans. Journal of Urology 169(4 Supplement): 155, April