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Refuse leachate exposure causes changes of thyroid hormone level and related gene expression in female goldfish (Carassius auratus)


, : Refuse leachate exposure causes changes of thyroid hormone level and related gene expression in female goldfish (Carassius auratus). Environmental Toxicology and Pharmacology 48(): 46-52

NlmCategory="UNASSIGNED">To elucidate the potential thyroid disrupting effects of refuse leachate on females, female goldfish (Carassius auratus) were exposed to 0.5% diluted leachates from each step of a leachate treatment process (i.e. raw leachate before treatment, after membrane bioreactor treatment, and the final treated leachate) for 21days. Raw leachate exposure caused disturbances in the thyroid cascade of female fish, as evidenced by the elevated plasma 3,3',5-triiodo-l-thyronine (p<0.05) and thyroid-stimulating hormone (p<0.01) levels as well as up-regulated hepatic and gonadal type I deiodinase (p<0.01), type II deiodinase (p<0.01) and thyroid receptor (p<0.05) mRNA levels. Thyroid disrupting potency decreased markedly as raw leachate progressed through the "membrane bioreactor + reverse osmosis" treatment but could still be detected in the treated leachate. As our results indicated, thyroid system in female goldfish was more sensitive to leachate exposure than that of the male fish.

US$19.90

PMID: 27736670

DOI: 10.1016/j.etap.2016.10.001


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Chida, N.; Kobayashi, I.; Takezaki, S.; Ueki, M.; Yamazaki, Y.; Garelli, S.; Scarpa, R.; Horikawa, R.; Yamada, M.; Betterle, C.; Notarangelo, L.D.; Yawaka, Y.; Ariga, T., 2015: Disease specificity of anti-tryptophan hydroxylase-1 and anti-AIE-75 autoantibodies in APECED and IPEX syndrome. Autoantibodies to autoimmune enteropathy-related 75 kDa antigen (AIE-75) and villin are disease markers of immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome which is characterized by a peripheral tolerance defect. On...

Sourie, R., 1954: Etude ecologique sommaire des forids sableux en Baie de Dakar. Ann Ecol super Sci Dakar, 1: 141-155

Gonzalez, E.; Marti, T.; Vinardell, M.P.lar, 1996: Comparative study of the small intestinal monosaccharide and amino acid transport as a function of age. Total proline and 3-oxy-methyl-D-glucose transport across jejunum and ileum of chicken aged 1 day to 100 days has been studied using a perfusion method in vivo and was determined as a function of body weight in the 7 age groups studied. The jejunu...

Robuschi, L., 1948: Electrophoretic migration velocity and membrane potential. Addition of electrolytes in minute amts. to a bacterial suspension in dist. water results in an increase cf electrophoretic migration velocity of the bacteria. The higher the valence and ionic velocity of the anion added, the more conspicuous the...

Thakur, N.M.; Perkel, R.L., 2003: Prevention in adulthood: forging a doctor-patient partnership. In this ever-changing health care system, Americans still retain confidence in their individual physicians [11]. This confidence represents an impressive fact when placed in the context of today's threats to the physician-patient relationship...

Cross Rodman Kay, 1943: Gato Ridge area of the Cat Canyon oil field. Pages 438-439 1943

Anonymous, 1851: Homoeopathy at Totness: Inquest. Provincial Medical & Surgical Journal 15(24): 664-665

Gelman, R., 1992: Statistical methods for early breast cancer trials. Cancer Treatment and Research 60: 27-53

Fernandes, A.J.; Diotaiuti, L.; Pinto Dias, J.C.; Romanha, A.J.; Chiari, E., 1989: Natural infection of opossum (Didelphis albiventris) anal glands by Trypanosoma cruzi in Bambui municipality, Minas Gerais State, Brazil. Of 87 Didelphis albiventris captured in the Bambui area, Minas Gerais, Brazil, from August 1986 to September 1987, 32 were found to be infected by Trypanosoma cruzi: rates of infection were 34.9 (22 of 63), 81.8 (9 of 11) and 7.7% (1 of 13) in syl...

Thorell, B., 1950: Further investigations of erythropoiesis. Nordisk Medicin 43(22): 920-921