+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Screening, evaluation, and management of cancer-related fatigue: Ready for implementation to practice?

, : Screening, evaluation, and management of cancer-related fatigue: Ready for implementation to practice?. Ca: A Cancer Journal for Clinicians 65(3): 190-211

Answer questions and earn CME/CNE Evidence regarding cancer-related fatigue (fatigue) has accumulated sufficiently such that recommendations for screening, evaluation, and/or management have been released recently by 4 leading cancer organizations. These evidence-based fatigue recommendations are available for clinicians, and some have patient versions; but barriers at the patient, clinician, and system levels hinder dissemination and implementation into practice. The underlying biologic mechanisms for this debilitating symptom have not been elucidated completely, hindering the development of mechanistically driven interventions. However, significant progress has been made toward methods for screening and comprehensively evaluating fatigue and other common symptoms using reliable and valid self-report measures. Limited data exist to support the use of any pharmacologic agent; however, several nonpharmacologic interventions have been shown to be effective in reducing fatigue in adults. Never before have evidence-based recommendations for fatigue management been disseminated by 4 premier cancer organizations (the National Comprehensive Cancer, the Oncology Nursing Society, the Canadian Partnership Against Cancer/Canadian Association of Psychosocial Oncology, and the American Society of Clinical Oncology). Clinicians may ask: Are we ready for implementation into practice? The reply: A variety of approaches to screening, evaluation, and management are ready for implementation. To reduce fatigue severity and distress and its impact on functioning, intensified collaborations and close partnerships between clinicians and researchers are needed, with an emphasis on system-wide efforts to disseminate and implement these evidence-based recommendations.


PMID: 25760293

DOI: 10.3322/caac.21268

Other references

Thomsen, B.; Horn, P.; Panitz, F.; Bendixen, Eøke.; Petersen, A.H.; Holm, L-Erik.; Nielsen, V.H.; Agerholm, Jørgen.S.; Arnbjerg, J.; Bendixen, C., 2005: A missense mutation in the bovine SLC35A3 gene, encoding a UDP-N-acetylglucosamine transporter, causes complex vertebral malformation. The extensive use of a limited number of elite bulls in cattle breeding can lead to rapid spread of recessively inherited disorders. A recent example is the globally distributed syndrome Complex Vertebral Malformation (CVM), which is characterized...

Brylski, P.; Hall, B.K., 1988: Ontogeny of a macroevolutionary phenotype: the external cheek pouches of geomyoid rodents. Evolution 42: 1-5

Ma, J.; Rong, L.; Zhou, Y.; Roy, B.Bushan.; Lu, J.; Abrahamyan, L.; Mouland, A.J.; Pan, Q.; Liang, C., 2008: The requirement of the DEAD-box protein DDX24 for the packaging of human immunodeficiency virus type 1 RNA. RNA helicases play important roles in RNA metabolism. Human immunodeficiency virus type 1 (HIV-1) does not carry its own RNA helicase, the virus thus needs to exploit cellular RNA helicases to promote the replication of its RNA at various steps s...

Salunke, P.; Sahoo, S.K.; Madhivanan, K.; Radotra, B.D., 2014: A typical radiological presentation in a case of choroid plexus carcinoma. Surgical Neurology International 5: 63-63

Sakomura, N.K.zue; Rostagno, H.S.ntiago; Torres, R.A.meida; Fonseca, J.B.andao, 1993: Effect of environmental temperature on the feed intake and on metabolizable energy intake in broilers breeders. One experiment was conducted in climatic chambers at a high, medium and low temperature at the Universidade Federal de Vicosa. The fortyfive broiler breeders, age 40 weeks, were fed diets "ad Libitum". The experimental design was complet...

Ilbey, Y.Ozlem.; Ozbek, E.; Simsek, A.; Otunctemur, A.; Cekmen, M.; Somay, A., 2008: Potential chemoprotective effect of melatonin in cyclophosphamide- and cisplatin-induced testicular damage in rats. To evaluate the effect of melatonin on cyclophosphamide (CP)- and cisplatin-induced testicular toxicity with use of sperm parameters and biochemical and histopathologic approaches. Experimental study. Vakif Gureba Hospital, Istanbul, Turkey. Six-w...

Arrufat, J.M.; Cervelló, E.; Pastor, J.M.; Isusquiza, J.I.; Casas, V.; Albella, F., 1979: Rupture of a single renal cyst in the excretory ducts. After observing one case, the authors review the contemporary literature on ruptures of single kidney cysts in the pyelo-calicial cavity. They comment upon the pathogenesis of this entity which is produced by an increase in the intracystic pressur...

Harper, D.M.; Groner, J.A.; Griffith, R.Stephen.; Harper, W.H., 2013: Re: Annual report to the nation on the status of cancer, 1975-2009, featuring the burden and trends in human papillomavirus (HPV)-associated cancers and HPV vaccination coverage levels and Re: Inequalities in human papillomavirus (HPV)-associated cancers: implications for the success of HPV vaccination. Journal of the National Cancer Institute 105(10): 749-750

Gudlet, M.A.; Kard0 Sysoyeva, E.K., 1938: The condition of vitamin C in plants. Structural elements of horse-radish, prepared in absence of O2, aid the reversible oxidation of reduced ascorbic acid; the nitrate aids the further destruction of dehydroascorbic acid. The filtrate is inactivated when both O2 and structural elemen...

Date, Elaine S., 1996: Late responses and nerve conduction studies in patients with low back pain. Kimura, J [Editor], Shibasaki, H [Editor] International Congress Series; Recent advances in clinical neurophysiology : 524-530